Ziprasidone vs Standard Therapy for Agitated Patients in the ED

George Washington University (GW)

Status and phase: Withdrawn; Phase 4

Conditions: Delirium; Agitation; Psychosis

Treatments: Drug: ziprasidone; Drug: Standard therapy

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00786318

010411 (completed)

Details and patient eligibility

About

The primary objective is to determine if ziprasidone is superior to standard therapies in the emergency department treatment of the acutely agitated patient. The primary outcome will be the length of time taken until the patient is ready to be evaluated by the psychiatric service, or until a disposition is made.

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acutely agitated
• Requires chemical sedation

Exclusion criteria

• Physician preference for a specific chemical sedative
• Known allergy to any study medications

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

0 participants in 2 patient groups

ziprasidone

Experimental group

Treatment:

Drug: ziprasidone

Standard therapy

Active Comparator group

Treatment:

Drug: Standard therapy