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The purpose of this study is to determine the clinical benefit of ASP2215 therapy in participants with FMS-like tyrosine kinase (FLT3) mutated acute...
Phase 3
Birmingham, Alabama, United States and 125 other locations
The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of JNJ-75276617 in combination with AML directed ...
Phase 1
Birmingham, Alabama, United States and 29 other locations
A Phase 1/2 dose escalation study of BCL-2 Inhibitor ZN-d5 and the Wee1 Inhibitor ZN-c3 in Subjects with Acute Myeloid Leukemia...
Phase 1, Phase 2
Birmingham, Alabama, United States and 12 other locations
Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Tuspetinib (HM43239) in Patients with Relapsed or Refractory Acute...
Phase 1, Phase 2
Birmingham, Alabama, United States and 33 other locations
This trial will seek to extend the preliminary findings of efficacy of MBG453 in combination with hypomethylating agents (HMA) by evaluating MBG453 i...
Phase 2
Birmingham, Alabama, United States and 27 other locations
in decreasing relapse after stem cell transplant and improving leukemia-free survival in pediatric patients with acute myeloid...
Phase 1, Phase 2
Birmingham, Alabama, United States and 4 other locations
This study is a Phase 2 multicenter study with a Safety Lead-in evaluating safety and efficacy of MT-401 administration to patients with AML...
Phase 2
Birmingham, Alabama, United States and 17 other locations
GDX012 is a novel cell therapy developed for the treatment of certain types of cancer, including Acute Myeloid Leukemia (A...
Phase 1, Phase 2
Birmingham, Alabama, United States and 13 other locations
This is a multi-center, randomized, double-blinded, placebo controlled trial.
Phase 3
Birmingham, Alabama, United States and 68 other locations
and pharmacokinetics, of CB-012 (the study treatment) in adults with acute myeloid leukemia (AML) that has come b...
Phase 1
Birmingham, Alabama, United States and 6 other locations
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