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Find clinical trials for Acute Myeloid Leukemia (AML) in Birmingham, AL

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Related conditions:

Acute Myeloid Leukemia
Leukemia
Myeloid Leukemia
Myelodysplastic Syndromes
Preleukemia
Syndrome
Cancer

Acute Myeloid Leukemia (AML) trials near Birmingham, AL, USA:

A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation

The purpose of this study is to determine the clinical benefit of ASP2215 therapy in participants with FMS-like tyrosine kinase (FLT3) mutated acute...

Active, not recruiting
Leukemia, Acute Myeloid (AML)
Drug: MEC (Mitoxantrone, Etoposide, Cytarabine)
Drug: gilteritinib

Phase 3

Astellas
Astellas

Birmingham, Alabama, United States and 125 other locations

to be used in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic s...

Enrolling
Relapsed Adult AML
Leukemia, Myeloid, Acute
Drug: Venetoclax Oral Tablet
Drug: Tuspetinib

Phase 1, Phase 2

Aptose Biosciences

Birmingham, Alabama, United States and 33 other locations

The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of bleximenib in combination with AML directed th...

Enrolling
Leukemia, Myeloid, Acute
Drug: Bleximenib
Drug: Daunorubicin or Idarubicin

Phase 1

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

Birmingham, Alabama, United States and 30 other locations

This trial will seek to extend the preliminary findings of efficacy of MBG453 in combination with hypomethylating agents (HMA) by evaluating MBG453 i...

Active, not recruiting
Acute Myeloid Leukemia
Drug: MBG453
Drug: Venetoclax

Phase 2

Novartis
Novartis

Birmingham, Alabama, United States and 27 other locations

This study is a Phase 2 multicenter study with a Safety Lead-in evaluating safety and efficacy of MT-401 administration to patients with AML...

Active, not recruiting
Acute Myeloid Leukemia
Stem Cell Transplantation
Drug: MT-401

Phase 2

Marker Therapeutics

Birmingham, Alabama, United States and 17 other locations

GDX012 is a novel cell therapy developed for the treatment of certain types of cancer, including Acute Myeloid Leukemia (A...

Enrolling
Leukemia
Drug: GDX012
Drug: Chemotherapy Agents

Phase 1, Phase 2

Takeda
Takeda

Birmingham, Alabama, United States and 13 other locations

and pharmacokinetics, of CB-012 (the study treatment) in adults with acute myeloid leukemia (AML) that has come b...

Enrolling
Acute Myeloid Leukemia Refractory
Acute Myeloid Leukemia, in Relapse
Drug: CB-012

Phase 1

Caribou Biosciences

Birmingham, Alabama, United States and 6 other locations

This is a multi-center, randomized, double-blinded, placebo controlled trial.

Enrolling
Adult Acute Myeloid Leukemia
Drug: mocravimod

Phase 3

Priothera

Birmingham, Alabama, United States and 91 other locations

with fludarabine and cytarabine in treating patients with acute myeloid leukemia (AML), myelodysplastic syndrome ...

Enrolling
Refractory Juvenile Myelomonocytic Leukemia
Refractory Childhood Acute Myeloid Leukemia
Drug: Cytarabine
Drug: Fludarabine

Phase 1

Children's Oncology Group

Birmingham, Alabama, United States and 7 other locations

if it is safe for patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). It will study SE...

Enrolling
Acute Myeloid Leukemia
Myelodysplastic Syndrome
Drug: SEA-CD70
Drug: azacitidine

Phase 1

Seagen
Seagen

Birmingham, Alabama, United States and 22 other locations

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