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The purpose of this study is to determine the clinical benefit of ASP2215 therapy in participants with FMS-like tyrosine kinase (FLT3) mutated acute...
Phase 3
Birmingham, Alabama, United States and 125 other locations
to be used in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic s...
Phase 1, Phase 2
Birmingham, Alabama, United States and 33 other locations
The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of bleximenib in combination with AML directed th...
Phase 1
Birmingham, Alabama, United States and 30 other locations
This trial will evaluate whether luveltamab tazevibulin is well tolerated and active against a rare form of AML carrying a particular geneti...
Phase 1, Phase 2
Birmingham, Alabama, United States and 3 other locations
This trial will seek to extend the preliminary findings of efficacy of MBG453 in combination with hypomethylating agents (HMA) by evaluating MBG453 i...
Phase 2
Birmingham, Alabama, United States and 27 other locations
GDX012 is a novel cell therapy developed for the treatment of certain types of cancer, including Acute Myeloid Leukemia (A...
Phase 1, Phase 2
Birmingham, Alabama, United States and 13 other locations
and pharmacokinetics, of CB-012 (the study treatment) in adults with acute myeloid leukemia (AML) that has come b...
Phase 1
Birmingham, Alabama, United States and 9 other locations
This is a multi-center, randomized, double-blinded, placebo controlled trial.
Phase 3
Birmingham, Alabama, United States and 92 other locations
with fludarabine and cytarabine in treating patients with acute myeloid leukemia (AML), myelodysplastic syndrome ...
Phase 1
Birmingham, Alabama, United States and 12 other locations
if it is safe for patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). It will study SE...
Phase 1
Birmingham, Alabama, United States and 22 other locations
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