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Find clinical trials for Acute Myeloid Leukemia (AML) in Birmingham, AL

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Related conditions:

Acute Myeloid Leukemia
Leukemia
Myeloid Leukemia
Myelodysplastic Syndromes
Preleukemia
Syndrome
Cancer

Acute Myeloid Leukemia (AML) trials near Birmingham, AL, USA:

A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation

The purpose of this study is to determine the clinical benefit of ASP2215 therapy in participants with FMS-like tyrosine kinase (FLT3) mutated acute...

Active, not recruiting
Leukemia, Acute Myeloid (AML)
Drug: LoDAC (Low Dose Cytarabine)
Drug: MEC (Mitoxantrone, Etoposide, Cytarabine)

Phase 3

Astellas
Astellas

Birmingham, Alabama, United States and 125 other locations

The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of JNJ-75276617 in combination with AML directed ...

Enrolling
Leukemia, Myeloid, Acute
Drug: Azacitidine (AZA)
Drug: Cytarabine

Phase 1

Janssen (J&J Innovative Medicine)
Janssen (J&J Innovative Medicine)

Birmingham, Alabama, United States and 30 other locations

A Phase 1/2 dose escalation study of BCL-2 Inhibitor ZN-d5 and the Wee1 Inhibitor ZN-c3 in Subjects with Acute Myeloid Leukemia...

Enrolling
Acute Myeloid Leukemia (AML)
Drug: ZN-c3
Drug: ZN-d5 ZN-c3

Phase 1, Phase 2

K-Group Alpha

Birmingham, Alabama, United States and 12 other locations

Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Tuspetinib (HM43239) in Patients with Relapsed or Refractory Acute...

Enrolling
Relapsed or Refractory Acute Myeloid Leukemia
Drug: Tuspetinib
Drug: Venetoclax Oral Tablet

Phase 1, Phase 2

Aptose Biosciences

Birmingham, Alabama, United States and 33 other locations

This trial will seek to extend the preliminary findings of efficacy of MBG453 in combination with hypomethylating agents (HMA) by evaluating MBG453 i...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Venetoclax
Drug: MBG453

Phase 2

Novartis
Novartis

Birmingham, Alabama, United States and 27 other locations

in decreasing relapse after stem cell transplant and improving leukemia-free survival in pediatric patients with acute myeloid...

Enrolling
Acute Myeloid Leukemia
Pediatric Cancer
Drug: Fludarabine
Drug: Busulfan

Phase 1, Phase 2

Malika Kapadia

Birmingham, Alabama, United States and 4 other locations

This study is a Phase 2 multicenter study with a Safety Lead-in evaluating safety and efficacy of MT-401 administration to patients with AML...

Active, not recruiting
Acute Myeloid Leukemia
Stem Cell Transplantation
Drug: MT-401

Phase 2

Marker Therapeutics

Birmingham, Alabama, United States and 17 other locations

GDX012 is a novel cell therapy developed for the treatment of certain types of cancer, including Acute Myeloid Leukemia (A...

Enrolling
Leukemia
Drug: Chemotherapy Agents
Drug: GDX012

Phase 1, Phase 2

Takeda
Takeda

Birmingham, Alabama, United States and 13 other locations

This is a multi-center, randomized, double-blinded, placebo controlled trial.

Enrolling
Adult Acute Myeloid Leukemia
Drug: mocravimod

Phase 3

Priothera

Birmingham, Alabama, United States and 71 other locations

and pharmacokinetics, of CB-012 (the study treatment) in adults with acute myeloid leukemia (AML) that has come b...

Enrolling
Acute Myeloid Leukemia Refractory
Acute Myeloid Leukemia, in Relapse
Drug: CB-012

Phase 1

Caribou Biosciences

Birmingham, Alabama, United States and 6 other locations

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