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PK of APG-2575 in combination with Azacitidine in the patients with AML/MPAL or MDS/CMML. The study consists of dose escalation (Part I) and...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 8 other locations
The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of bleximenib in combination with AML directed th...
Phase 1
Charlotte, North Carolina, United States and 32 other locations
subjects with previously treated or untreated with high risk factor acute myeloid leukemia (AML). Venetoclax and ...
Phase 1
Charlotte, North Carolina, United States and 3 other locations
cytotoxic chemotherapy in induction-eligible patients with acute myeloid leukemia.This study involves the following:* Vene...
Phase 2
Charlotte, North Carolina, United States and 8 other locations
). Both parts will be conducted in participants with previously untreated CD123+ AML who are ineligible for intensive chemotherapy....
Phase 2
Charlotte, North Carolina, United States and 35 other locations
drug cusatuzumab added to venetoclax and azacitidine works to treat acute myeloid leukemia (AML) compared to vene...
Phase 2
Charlotte, North Carolina, United States and 26 other locations
be tolerable and active in pediatric patients with newly diagnosed acute myeloid leukemia (AML).Primary Objective...
Phase 2
Charlotte, North Carolina, United States and 5 other locations
standard of care treatments for patients with relapsed/refractory acute myeloid leukemia will be examined with the followi...
Phase 1
Charlotte, North Carolina, United States and 24 other locations
Some people with MDS have a risk of the disease progressing to acute myeloid leukemia (AML), and a risk of death ...
Phase 3
Charlotte, North Carolina, United States and 221 other locations
This is a phase I/II Study of Nivolumab in Combination with 5-azacytidine in pediatric patients with relapsed/refractory acute myeloid...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 11 other locations
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