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PK of APG-2575 in combination with Azacitidine in the patients with AML/MPAL or MDS/CMML. The study consists of dose escalation (Part I) and...
Phase 1, Phase 2
Charlotte, North Carolina, United States and 8 other locations
The purpose of this study is to determine the recommended Phase 2 dose (RP2D) candidate(s) of bleximenib in combination with AML directed th...
Phase 1
Charlotte, North Carolina, United States and 33 other locations
subjects with previously treated or untreated with high risk factor acute myeloid leukemia (AML). Venetoclax and ...
Phase 1
Charlotte, North Carolina, United States and 3 other locations
cytotoxic chemotherapy in induction-eligible patients with acute myeloid leukemia.This study involves the following:* Vene...
Phase 2
Charlotte, North Carolina, United States and 8 other locations
). Both parts will be conducted in participants with previously untreated CD123+ AML who are ineligible for intensive chemotherapy....
Phase 2
Charlotte, North Carolina, United States and 31 other locations
VEN+AZA alone for the treatment of participants with newly diagnosed Acute Myeloid Leukemia (AML) with a mutation...
Phase 3
Charlotte, North Carolina, United States and 265 other locations
tyrosine kinase 3 (FLT3)-internal tandem duplication (ITD) (+) acute myeloid leukemia (AML) in first complete rem...
Phase 2
Charlotte, North Carolina, United States and 63 other locations
be tolerable and active in pediatric patients with newly diagnosed acute myeloid leukemia (AML).Primary Objective...
Phase 2
Charlotte, North Carolina, United States and 9 other locations
standard of care treatments for patients with relapsed/refractory acute myeloid leukemia will be examined with the followi...
Phase 1
Charlotte, North Carolina, United States and 44 other locations
Some people with MDS have a risk of the disease progressing to acute myeloid leukemia (AML), and a risk of death ...
Phase 3
Charlotte, North Carolina, United States and 223 other locations
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