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The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...
Phase 3
Cleveland, Ohio, United States and 164 other locations
to be used in future studies in study participants diagnosed with acute myeloid leukemia (AML), myelodysplastic s...
Phase 1, Phase 2
Cleveland, Ohio, United States and 33 other locations
allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid...
Phase 3
Cleveland, Ohio, United States and 23 other locations
to venetoclax + azacitidine in adults recently diagnosed with AML who are unable to be treated with intensive chemotherapy.Participants will...
Phase 2
Cleveland, Ohio, United States and 56 other locations
Ziftomenib is an investigational drug in development for the treatment of patients with acute myeloid leukemia (AML...
Phase 1
Cleveland, Ohio, United States and 43 other locations
Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 70 will be randomiz...
Phase 2
Cleveland, Ohio, United States and 43 other locations
to placebo and VEN+AZA alone for the treatment of participants with Acute Myeloid Leukemia (AML) with a mutation ...
Phase 3
Cleveland, Ohio, United States and 140 other locations
). Both parts will be conducted in participants with previously untreated CD123+ AML who are ineligible for intensive chemotherapy....
Phase 2
Cleveland, Ohio, United States and 32 other locations
GDX012 is a novel cell therapy developed for the treatment of certain types of cancer, including Acute Myeloid Leukemia (A...
Phase 1, Phase 2
Cleveland, Ohio, United States and 13 other locations
The purpose of this study is to evaluate safety and tolerability and to determine the maximum tolerated dose (MTD) and/or recommended dose (RD) of SG...
Phase 1
Cleveland, Ohio, United States and 11 other locations
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