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Find clinical trials for Acute Myeloid Leukemia (AML) in Detroit, MI

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Related conditions:

Acute Myeloid Leukemia
Leukemia
Myeloid Leukemia
Myelodysplastic Syndromes
Preleukemia
Syndrome
Cancer

Acute Myeloid Leukemia (AML) trials near Detroit, MI, USA:

A Study of ASP2215 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML) With FMS-like Tyrosine Kinase (FLT3) Mutation

The purpose of this study is to determine the clinical benefit of ASP2215 therapy in participants with FMS-like tyrosine kinase (FLT3) mutated acute...

Active, not recruiting
Leukemia, Acute Myeloid (AML)
Drug: LoDAC (Low Dose Cytarabine)
Drug: MEC (Mitoxantrone, Etoposide, Cytarabine)

Phase 3

Astellas
Astellas

Detroit, Michigan, United States and 125 other locations

The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Cancer
Other: Best Supportive Care (BSC)
Drug: Venetoclax

Phase 3

AbbVie
AbbVie

Detroit, Michigan, United States and 164 other locations

Anti-tumor Activity of LYT- 200 in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML), or with Relaps...

Enrolling
AML, Adult Recurrent
MDS
Drug: Decitabine
Drug: LYT-200

Phase 1

PureTech Health

Detroit, Michigan, United States and 10 other locations

\[GO\]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse w...

Enrolling
Acute Myeloid Leukemia
Drug: Venetoclax
Drug: Fludarabine

Phase 3

LLS PedAL Initiative, LLC

Detroit, Michigan, United States and 73 other locations

combination with all-trans retinoic acid (ATRA) in participants with acute myeloid leukemia (AML) who have relaps...

Active, not recruiting
Acute Myeloid Leukemia
Drug: TAS1440 + ATRA
Drug: TAS1440

Phase 1

Astex Pharmaceuticals
Astex Pharmaceuticals

Ann Arbor, Michigan, United States and 7 other locations

Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 70 will be randomiz...

Active, not recruiting
Acute Myeloid Leukemia
Drug: Gilteritinib
Drug: Daunorubicin

Phase 2

PrECOG

Ann Arbor, Michigan, United States and 43 other locations

Refractory Myelodysplastic Syndromes (MDS), Chronic Myelomonocytic Leukemia (CMML), or Acute Myeloid Leukemia (AML...

Active, not recruiting
Relapsed Adult AML
AML/MDS
Drug: LP-108 and azacitidine
Drug: LP-108

Phase 1

Newave Pharmaceutical

Ann Arbor, Michigan, United States and 6 other locations

inhibitor of MDM2 for the treatment of adults with FLT3 mutated Acute Myeloid Leukemia. Participants must be relapsed/refr...

Active, not recruiting
Acute Myeloid Leukemia
Drug: TL-895
Drug: KRT-232

Phase 1, Phase 2

Telios Pharma

Detroit, Michigan, United States and 34 other locations

which contains populations of CD8+ T cells targeting multiple leukemia associated antigen peptides in patients with Acute Myeloid...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndrome (MDS)
Biological: Infusion of NEXI-001 T Cells

Phase 1, Phase 2

NexImmune

Detroit, Michigan, United States and 4 other locations

menin-MLL(KMT2A) inhibitor, in patients with relapsed or refractory acute myeloid leukemia (AML) as part of Phase....

Enrolling
Acute Leukemia of Ambiguous Lineage
Mixed Phenotype Acute Leukemia
Drug: Ziftomenib

Phase 1, Phase 2

Kura Oncology

Detroit, Michigan, United States and 51 other locations

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