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Find clinical trials for Acute Myeloid Leukemia (AML) in Orlando, FL

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Related conditions:

Acute Myeloid Leukemia
Leukemia
Myeloid Leukemia
Myelodysplastic Syndromes
Preleukemia
Syndrome
Cancer

Acute Myeloid Leukemia (AML) trials near Orlando, FL, USA:

A Study Evaluating Safety and Efficacy of Venetoclax in Combination With Azacitidine Versus Standard of Care After Allogeneic Stem Cell Transplantation (SCT) in Participants With Acute Myeloid Leukemia (AML) (VIALE-T)

The main objective of this study is to evaluate the efficacy of venetoclax in combination with azacitidine to improve Overall Survival (OS) in Acute...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Cancer
Other: Best Supportive Care (BSC)
Drug: Venetoclax

Phase 3

AbbVie
AbbVie

Orlando, Florida, United States and 164 other locations

A Study of Pevonedistat and Venetoclax Combined With Azacitidine to Treat Acute Myeloid Leukemia (AML) in Adults Unable to Receive Intensive Chemotherapy (PEVENAZA)

to venetoclax + azacitidine in adults recently diagnosed with AML who are unable to be treated with intensive chemotherapy.Participants will...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Drug: Venetoclax
Drug: Pevonedistat

Phase 2

Takeda
Takeda

Orlando, Florida, United States and 56 other locations

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

[GO]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse who...

Enrolling
Acute Myeloid Leukemia
Drug: Fludarabine
Drug: Cytarabine

Phase 3

LLS PedAL Initiative, LLC

Orlando, Florida, United States and 71 other locations

Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remission (QUAZAR AML-001)

This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) ...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Placebo
Drug: Oral Azacitidine

Phase 3

Celgene
Celgene

Orlando, Florida, United States and 222 other locations

A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors

three separate safety run-in cohorts in neuroblastoma, acute myeloid leukemia (AML), and acute lymphobla...

Active, not recruiting
Acute Lymphoblastic Leukemia (ALL)
Acute Myeloid Leukemia (AML)
Drug: Fludarabine
Drug: Idasanutlin

Phase 1, Phase 2

Roche
Roche

Orlando, Florida, United States and 19 other locations

Antigen-specific T Cell Therapy for AML or MDS Patients With Relapsed Disease After Allo-HCT

which contains populations of CD8+ T cells targeting multiple leukemia associated antigen peptides in patients with Acute Myeloid...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndrome (MDS)
Biological: Infusion of NEXI-001 T Cells

Phase 1, Phase 2

NexImmune

Orlando, Florida, United States and 4 other locations

Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants With Relapsed, Refractory, or Newly Diagnosed Cancers

This study is a first-in-human, Phase 1a/1b, multicenter, open-label study to determine the safety, tolerability, and pharmacokinetics of aplitabart...

Enrolling
Chronic Lymphocytic Leukemia
Acute Myeloid Leukemia
Drug: Bevacizumab (and approved biosimilars)
Drug: FOLFIRI

Phase 1

IGM Biosciences

Lake Mary, Florida, United States and 57 other locations

Trial of DFP-10917 vs Non-Intensive or Intensive Reinduction for AML Patients in 2nd/3rd/4th Salvage

Phase III, multicenter, randomized study with two arms (1:1 ratio) enrolling patients with AML relapsed/refractory after 2, 3, or 4 prior in...

Enrolling
Leukemia, Myeloid, Acute
Drug: Cladribine
Drug: Venetoclax

Phase 3

Delta-Fly Pharma

Orlando, Florida, United States and 38 other locations

Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Low-Blast Acute Myelogenous Leukemia (AML) (PANTHER)

azacitidine. (An event is defined as death or transformation to AML in participants with MDS or CMML, whichever occurs first, and is defined...

Active, not recruiting
Leukemia, Myeloid, Acute
Leukemia, Myelomonocytic, Chronic
Drug: Pevonedistat
Drug: Azacitidine

Phase 3

Takeda
Takeda

Orlando, Florida, United States and 240 other locations

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