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Find clinical trials for Acute Myeloid Leukemia (AML) in St Louis, MO

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Related conditions:

Acute Myeloid Leukemia
Leukemia
Myeloid Leukemia
Myelodysplastic Syndromes
Preleukemia
Syndrome
Cancer

Acute Myeloid Leukemia (AML) trials near St Louis, MO, USA:

Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia (SIERRA)

allogeneic hematopoietic stem cell transplant (HCT), versus Conventional Care in patients with Active, Relapsed or Refractory Acute Myeloid...

Active, not recruiting
AML
Acute Myelogenous Leukemia
Drug: Conventional Care
Drug: Iomab-B

Phase 3

Actinium Pharmaceuticals
Actinium Pharmaceuticals

Saint Louis, Missouri, United States and 23 other locations

Flotetuzumab for Relapsed Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Following Allogeneic Hematopoietic Cell Transplantation (Allo-HCT)

The investigators hypothesize that flotetuzumab for relapsed AML following allo-HCT will be safe, tolerable and may facilitate preferential ...

Enrolling
Relapsed Acute Myeloid Leukemia
Drug: Flotetuzumab
Procedure: Donor lymphocyte infusion

Phase 2

The Washington University
The Washington University

Saint Louis, Missouri, United States

A Phase 1 Study of WU-NK-101 in Patients With Relapsed or Refractory (R/R) Acute Myeloid Leukemia (AML)

the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary anti-leukemic activity of WU-NK-101 in R/R AML....

Enrolling
Acute Myeloid Leukemia
Biological: WU-NK-101

Phase 1

Wugen, Inc.

Saint Louis, Missouri, United States and 8 other locations

Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood

or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or i...

Enrolling
Acute Myeloid Leukemia
Drug: Quizartinib
Drug: Etoposide

Phase 1, Phase 2

Daiichi Sankyo
Daiichi Sankyo

Saint Louis, Missouri, United States and 36 other locations

Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

[GO]) improves survival of children/adolescents/young adults with acute myeloid leukemia (AML) in 1st relapse who...

Enrolling
Acute Myeloid Leukemia
Drug: Fludarabine
Drug: Cytarabine

Phase 3

LLS PedAL Initiative, LLC

Saint Louis, Missouri, United States and 71 other locations

A Study of ASP2215 (Gilteritinib) by Itself, ASP2215 Combined With Azacitidine or Azacitidine by Itself to Treat Adult Patients Who Have Recently Been Diagnosed With Acute Myeloid Leukemia With a FLT3 Gene Mutation and Who Cannot Receive Standard Chemotherapy

This is a clinical study for adult patients who have recently been diagnosed with acute myeloid leukemia or AML. ...

Active, not recruiting
Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) Mutation
Acute Myeloid Leukemia (AML)
Drug: gilteritinib
Drug: azacitidine

Phase 3

Astellas
Astellas

Saint Louis, Missouri, United States and 110 other locations

A Study of Oral Venetoclax Tablets and Oral Azacitidine Versus Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy (VIALE-M)

This study will be conducted in two parts. Part 1 will be the Dose Confirmation portion to determine recommended Phase 3 dose (RPTD) of venetoclax in...

Active, not recruiting
Acute Myeloid Leukemia (AML)
Drug: CC-486
Drug: Venetoclax

Phase 3

AbbVie
AbbVie

Saint Louis, Missouri, United States and 157 other locations

Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remission (QUAZAR AML-001)

This study enrolled 472 participants, aged 55 or older, with a diagnosis of de novo acute myeloid leukemia (AML) ...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: Placebo
Drug: Oral Azacitidine

Phase 3

Celgene
Celgene

Saint Louis, Missouri, United States and 222 other locations

Locations recently updated

Allogeneic Engineered Hematopoietic Stem Cell Transplant (HCT) Lacking the CD33 Protein, and Post-HCT Treatment With Mylotarg, for Patients With CD33+ AML or MDS

This is a Phase 1/2a, multicenter, open-label, first-in-human (FIH) study of VOR33 in participants with AML or MDS who are undergoing human ...

Enrolling
Leukemia, Myeloid, Acute
Myelodysplastic Syndromes
Biological: VOR33
Drug: Mylotarg

Phase 1, Phase 2

Vor Biopharma

Saint Louis, Missouri, United States and 10 other locations

A Safety and Efficacy Study of CC-90009 Combinations in Subjects With Acute Myeloid Leukemia

CC-90009-AML-002 is an exploratory Phase 1b, open-label, multi-arm trial to evaluate the safety and efficacy of CC-90009 in combination with ...

Active, not recruiting
Leukemia, Myeloid, Acute
Drug: CC-90009
Drug: Azacitidine

Phase 1, Phase 2

Celgene
Celgene

Saint Louis, Missouri, United States and 13 other locations

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