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Find clinical trials for Adenocarcinoma in Boston, MA

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Carcinoma
Cancer
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Colorectal Cancer
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Esophageal Cancer

Adenocarcinoma trials near Boston, MA, USA:

Study of Pembrolizumab in Locally Advanced Esophageal Adenocarcinoma

with chemotherapy and chemoradiation in locally advanced esophageal adenocarcinoma to examine the safety and efficacy of the combination of ...

Active, not recruiting
Esophageal Adenocarcinoma
Drug: Carboplatin
Drug: Pembrolizumab

Phase 2

Weill Cornell Medicine (WCM)
Weill Cornell Medicine (WCM)

Providence, Rhode Island, United States and 3 other locations

for front line treatment of locally-advanced pancreatic adenocarcinoma.The device is an experimental, portable, battery operated device for ...

Active, not recruiting
Pancreas Adenocarcinoma
Drug: Gemcitabine
Drug: nab paclitaxel

Phase 3

NovoCure
NovoCure

Boston, Massachusetts, United States and 197 other locations

adenocarcinoma. Participants will receive immunotherapy (cemiplimab) which activates the body's immune system to attack cancer cells. Cemip...

Enrolling
Adenocarcinoma of the Pancreas
Adenocarcinoma
Drug: Gemcitabine
Drug: Cemiplimab

Phase 2

Gulam Manji

Providence, Rhode Island, United States and 1 other location

This study is being done to test the safety and effectiveness of combining ZN-c3 and Gemcitabine in participants with pancreatic cancer.The names of...

Enrolling
Pancreatic Ductal Adenocarcinoma
Advanced Pancreatic Adenocarcinoma
Drug: Gemzar
Drug: Zentalis

Phase 2

Brandon Huffman

Boston, Massachusetts, United States

combinations in participants with metastatic Pancreatic Ductal Adenocarcinoma (PDAC).Two cohorts will be enrolled in parallel in this study:...

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Fluorouracil
Drug: RO6874281

Phase 1, Phase 2

Roche
Roche

Boston, Massachusetts, United States and 26 other locations

The purpose of this Phase II study is to assess the efficacy and safety of NIS793 with and without spartalizumab in combination with gemcitabine/nab-...

Active, not recruiting
Metastatic Pancreatic Ductal Adenocarcinoma
Drug: nab-paclitaxel
Biological: NIS793

Phase 2

Novartis
Novartis

Boston, Massachusetts, United States and 30 other locations

will be eligible for screening: unresectable or metastatic gastric adenocarcinoma, gastroesophageal junction (GEJ) adenocarcinoma, ...

Enrolling
Pancreatic Ductal Adenocarcinoma
Gastric or Gastroesophageal Junction Adenocarcinoma
Drug: KEYTRUDA® (pembrolizumab)
Drug: Gemcitabine

Phase 1, Phase 2

Phanes Therapeutics

Boston, Massachusetts, United States and 3 other locations

The purpose of this study is to find out if an experimental drug will prevent metastatic pancreatic adenocarcinoma from becoming resistant t...

Enrolling
Pancreatic Adenocarcinoma Metastatic
Pancreatic Adenocarcinoma
Drug: FOLFIRNINOX
Drug: 9-ING-41

Phase 2

Colin D. Weekes, M.D., PhD

Boston, Massachusetts, United States and 2 other locations

as First-Line or Second-Line Therapy in Adult Patients with Inoperable, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma...

Active, not recruiting
Gastric Adenocarcinoma
Gastric Cancer
Drug: Capecitabine 1000mg/ m2 BID
Drug: DKN-01 600mg

Phase 2

Leap Therapeutics

Boston, Massachusetts, United States and 47 other locations

mFOLFIRINOX alone in participants with resected pancreatic ductal adenocarcinoma (PDAC) who have not received prior systemic anti-cancer tre...

Enrolling
Adenocarcinoma, Pancreatic Ductal
Drug: mFOLFIRINOX
Drug: Autogene cevumeran

Phase 2

Genentech
Genentech

Boston, Massachusetts, United States and 21 other locations

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