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Find clinical trials for Adenocarcinoma in Boston, MA

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Related conditions:

Pancreatic Cancer
Colorectal Cancer
Stomach Cancer
Non-Small-Cell Lung Carcinoma
Prostatic Cancer
Neoplasm Metastasis
Esophageal Cancer

Adenocarcinoma trials near Boston, MA, USA:

Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma (RASolute 303)

The purpose of this study is to evaluate the safety and efficacy of an investigational RAS(ON) inhibitor administered as monotherapy or in combinatio...

Enrolling
Pancreatic Adenocarcinoma Metastatic
PDAC - Pancreatic Ductal Adenocarcinoma
Drug: daraxonrasib
Drug: nab-paclitaxel

Phase 3

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 81 other locations

with chemotherapy and chemoradiation in locally advanced esophageal adenocarcinoma to examine the safety and efficacy of the combination of ...

Active, not recruiting
Esophageal Adenocarcinoma
Drug: Carboplatin
Drug: Pembrolizumab

Phase 2

Weill Cornell Medicine (WCM)
Weill Cornell Medicine (WCM)

Providence, Rhode Island, United States and 3 other locations

The purpose of this study is to evaluate the efficacy of an investigational RAS(ON) inhibitor administered in combination with chemotherapy compared...

Enrolling
Pancreatic Adenocarcinoma Metastatic
PDAC - Pancreatic Ductal Adenocarcinoma
Drug: Gemcitabine (GEM)
Drug: Nab-paclitaxel

Phase 3

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 19 other locations

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.

Enrolling
Resected Pancreatic Adenocarcinoma
PDAC - Pancreatic Ductal Adenocarcinoma
Drug: daraxonrasib

Phase 3

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 85 other locations

The purpose of this study is to find out if an experimental drug will prevent metastatic pancreatic adenocarcinoma from becoming resistant t...

Active, not recruiting
Pancreatic Adenocarcinoma Metastatic
Pancreatic Adenocarcinoma
Drug: FOLFIRNINOX
Drug: Losartan

Phase 2

Colin D. Weekes, M.D., PhD

Boston, Massachusetts, United States and 3 other locations

This Phase 1 interventional treatment study is evaluating oral daraxonrasib in participants with resectable pancreatic ductal adenocarcinoma...

Begins enrollment in 5 months
Resectable Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma
Procedure: Surgical Resection
Radiation: Adjuvant Radiation Therapy

Phase 1

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Boston, Massachusetts, United States and 1 other location

adenocarcinoma. Participants will receive immunotherapy (cemiplimab) which activates the body's immune system to attack cancer cells. Cemip...

Active, not recruiting
Adenocarcinoma of the Pancreas
Adenocarcinoma
Drug: Gemcitabine
Drug: Cemiplimab

Phase 2

Columbia University
Columbia University

Boston, Massachusetts, United States and 4 other locations

(CLDN18.2)-positive, human epidermal growth factor receptor 2 (HER2)-negative, gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Enrolling
Gastroesophageal Junction Adenocarcinoma
Esophageal Cancer
Drug: Sonesitatug vedotin
Drug: Nivolumab

Phase 3

AstraZeneca
AstraZeneca

Boston, Massachusetts, United States and 312 other locations

unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma trial is to compare OS between cadonilimab combined with...

Enrolling
Gastric / Gastroesophageal Junction Adenocarcinoma
Drug: CAPOX regimen
Drug: Cadonilimab

Phase 3

Akeso
Akeso

Boston, Massachusetts, United States and 24 other locations

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.

Active, not recruiting
PDAC - Pancreatic Ductal Adenocarcinoma
PDAC
Drug: 5-fluorouracil
Drug: leucovorin

Phase 3

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 59 other locations

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