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Find clinical trials for Adenocarcinoma in Boston, MA

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Adenocarcinoma trials near Boston, MA, USA:

Study of Pembrolizumab in Locally Advanced Esophageal Adenocarcinoma

with chemotherapy and chemoradiation in locally advanced esophageal adenocarcinoma to examine the safety and efficacy of the combination of ...

Active, not recruiting
Esophageal Adenocarcinoma
Drug: Carboplatin
Drug: Pembrolizumab

Phase 2

Weill Cornell Medicine (WCM)
Weill Cornell Medicine (WCM)

Providence, Rhode Island, United States and 3 other locations

adenocarcinoma. Participants will receive immunotherapy (cemiplimab) which activates the body's immune system to attack cancer cells. Cemip...

Enrolling
Adenocarcinoma of the Pancreas
Adenocarcinoma
Drug: Gemcitabine
Drug: Cemiplimab

Phase 2

Gulam Manji

Providence, Rhode Island, United States and 1 other location

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.

Enrolling
PDAC - Pancreatic Ductal Adenocarcinoma
PDAC
Drug: 5-fluorouracil
Drug: leucovorin

Phase 3

Revolution Medicines
Revolution Medicines

Boston, Massachusetts, United States and 38 other locations

This study is being done to test the safety and effectiveness of combining ZN-c3 and Gemcitabine in participants with pancreatic cancer.The names of...

Enrolling
Pancreatic Ductal Adenocarcinoma
Advanced Pancreatic Adenocarcinoma
Drug: Gemzar
Drug: Zentalis

Phase 2

Brandon Huffman, MD

Boston, Massachusetts, United States

The purpose of this study is to find out if an experimental drug will prevent metastatic pancreatic adenocarcinoma from becoming resistant t...

Enrolling
Pancreatic Adenocarcinoma Metastatic
Pancreatic Adenocarcinoma
Drug: FOLFIRNINOX
Drug: 9-ING-41

Phase 2

Colin D. Weekes, M.D., PhD

Boston, Massachusetts, United States and 2 other locations

as First-Line or Second-Line Therapy in Adult Patients with Inoperable, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma...

Active, not recruiting
Gastric Adenocarcinoma
Gastric Cancer
Drug: Tislelizumab 200mg
Drug: DKN-01 400mg

Phase 2

Leap Therapeutics

Boston, Massachusetts, United States and 47 other locations

The main goal of this study is to look at the effectiveness and anti-tumor activity (preventing growth of the tumor) of the drugs niraparib and ipili...

Begins enrollment this month
Pancreatic Adenocarcinoma Metastatic
Drug: FOLFIRI
Drug: Ipilimumab

Phase 2

Abramson Cancer Center at Penn Medicine
Abramson Cancer Center at Penn Medicine

Boston, Massachusetts, United States and 1 other location

participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignatur...

Enrolling
Endometrial Adenocarcinoma
Urothelial Carcinoma
Diagnostic Test: OncoSignature
Drug: ACR-368

Phase 1, Phase 2

Acrivon Therapeutics

Boston, Massachusetts, United States and 66 other locations

This is a Phase 1 study to assess the safety and efficacy of ELI-002 immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide \[Amph-CpG-...

Active, not recruiting
Pancreatic Ductal Adenocarcinoma
NRAS G12D
Drug: ELI-002 2P

Phase 1

Elicio Therapeutics
Elicio Therapeutics

Boston, Massachusetts, United States and 9 other locations

first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Active, not recruiting
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Drug: Domvanalimab
Drug: Zimberelimab

Phase 3

Arcus Biosciences
Arcus Biosciences

Boston, Massachusetts, United States and 203 other locations

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