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Find clinical trials for Adenocarcinoma in Boston, MA

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Adenocarcinoma trials near Boston, MA, USA:

Study of Pembrolizumab in Locally Advanced Esophageal Adenocarcinoma

with chemotherapy and chemoradiation in locally advanced esophageal adenocarcinoma to examine the safety and efficacy of the combination of ...

Active, not recruiting
Esophageal Adenocarcinoma
Drug: Carboplatin
Drug: Pembrolizumab

Phase 2

Weill Cornell Medicine (WCM)
Weill Cornell Medicine (WCM)

Providence, Rhode Island, United States and 3 other locations

adenocarcinoma. Participants will receive immunotherapy (cemiplimab) which activates the body's immune system to attack cancer cells. Cemip...

Enrolling
Adenocarcinoma of the Pancreas
Adenocarcinoma
Drug: Gemcitabine
Drug: Cemiplimab

Phase 2

Gulam Manji

Providence, Rhode Island, United States and 1 other location

This study is being done to test the safety and effectiveness of combining ZN-c3 and Gemcitabine in participants with pancreatic cancer.The names of...

Enrolling
Pancreatic Ductal Adenocarcinoma
Advanced Pancreatic Adenocarcinoma
Drug: Gemzar
Drug: Zentalis

Phase 2

Brandon Huffman

Boston, Massachusetts, United States

combinations in participants with metastatic Pancreatic Ductal Adenocarcinoma (PDAC).Two cohorts will be enrolled in parallel in this study:...

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Gemcitabine
Drug: Bevacizumab

Phase 1, Phase 2

Roche
Roche

Boston, Massachusetts, United States and 26 other locations

Locations recently updated

will be eligible for screening: unresectable or metastatic gastric adenocarcinoma, gastroesophageal junction (GEJ) adenocarcinoma, ...

Enrolling
Pancreatic Ductal Adenocarcinoma
Gastric or Gastroesophageal Junction Adenocarcinoma
Drug: FOLFIRINOX
Drug: KEYTRUDA® (pembrolizumab)

Phase 1, Phase 2

Phanes Therapeutics

Boston, Massachusetts, United States of America and 5 other locations

The purpose of this study is to find out if an experimental drug will prevent metastatic pancreatic adenocarcinoma from becoming resistant t...

Enrolling
Pancreatic Adenocarcinoma Metastatic
Pancreatic Adenocarcinoma
Drug: FOLFIRNINOX
Drug: 9-ING-41

Phase 2

Colin D. Weekes, M.D., PhD

Boston, Massachusetts, United States and 2 other locations

as First-Line or Second-Line Therapy in Adult Patients with Inoperable, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma...

Active, not recruiting
Gastric Adenocarcinoma
Gastric Cancer
Drug: Tislelizumab 200mg
Drug: DKN-01 400mg

Phase 2

Leap Therapeutics

Boston, Massachusetts, United States and 47 other locations

mFOLFIRINOX alone in participants with resected pancreatic ductal adenocarcinoma (PDAC) who have not received prior systemic anti-cancer tre...

Enrolling
Adenocarcinoma, Pancreatic Ductal
Drug: mFOLFIRINOX
Drug: Autogene cevumeran

Phase 2

Genentech
Genentech

Boston, Massachusetts, United States and 44 other locations

participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignatur...

Enrolling
Endometrial Adenocarcinoma
Urothelial Carcinoma
Diagnostic Test: OncoSignature
Drug: ACR-368

Phase 1, Phase 2

Acrivon Therapeutics

Boston, Massachusetts, United States and 66 other locations

This is a Phase 1 study to assess the safety and efficacy of ELI-002 immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide \[Amph-CpG-...

Active, not recruiting
Pancreatic Ductal Adenocarcinoma
NRAS G12D
Drug: ELI-002 2P

Phase 1

Elicio Therapeutics
Elicio Therapeutics

Boston, Massachusetts, United States and 9 other locations

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