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participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignatur...
Phase 1, Phase 2
Cleveland, Ohio, United States and 67 other locations
first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...
Phase 3
Cleveland, Ohio, United States and 212 other locations
The goal of this clinical trial is to test an experimental treatment (immunotherapy) in pancreatic cancer patients. The main research objectives are:...
Phase 1
Cleveland, Ohio, United States and 14 other locations
as monotherapy (Part C) and in combination with first-line SoC treatment (Part D) in patients with advanced or metastatic pancreatic adenocarcinoma...
Phase 1, Phase 2
Cleveland, Ohio, United States and 7 other locations
This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody ta...
Phase 1
Cleveland, Ohio, United States and 18 other locations
This trial studies tucatinib to find out if it is safe when given with trastuzumab and other anti-cancer drugs (pembrolizumab, FOLFOX, and CAPOX). It...
Phase 1, Phase 2
Cleveland, Ohio, United States and 21 other locations
This is a first-in-human, open-label, multi-center, Phase 1, dose-escalation study with expansion cohorts to evaluate NM32-2668 for safety and immuno...
Phase 1
Cleveland, Ohio, United States and 4 other locations
This study is open to adults with advanced cancer in the biliary tract, pancreas, lung, or bladder. This is a study for people for whom previous trea...
Phase 2
Cleveland, Ohio, United States and 65 other locations
participants with hepatocellular carcinoma (HCC), pancreatic ductal adenocarcinoma (PDAC), biliary tract cancers (BTC), esophageal squamous ...
Phase 1
Cleveland, Ohio, United States and 36 other locations
This trial will look at a drug called sigvotatug vedotin (SGN-B6A) alone and with pembrolizumab, with or without chemotherapy, to find out whether it...
Phase 1
Cleveland, Ohio, United States and 22 other locations
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