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Find clinical trials for Adenocarcinoma in Cleveland, OH

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Pancreatic Cancer
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Colorectal Cancer
Stomach Cancer
Esophageal Cancer
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Adenocarcinoma trials near Cleveland, OH, USA:

Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

The objective of this study is to assess safety and efficacy of BA3182 in Advanced Adenocarcinoma...

Enrolling
Advanced Adenocarcinoma
Drug: BA3182

Phase 1

BioAtla

Cleveland, Ohio, United States and 8 other locations

(CLDN18.2)-positive, human epidermal growth factor receptor 2 (HER2)-negative, gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Enrolling
Gastroesophageal Junction Adenocarcinoma
Esophageal Cancer
Drug: Sonesitatug vedotin
Drug: Nivolumab

Phase 3

AstraZeneca
AstraZeneca

Cleveland, Ohio, United States and 229 other locations

The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...

Active, not recruiting
Metastatic Pancreatic Ductal Adenocarcinoma
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 3

Arcus Biosciences
Arcus Biosciences

Cleveland, Ohio, United States and 124 other locations

Locations recently updated

in individuals with pathologically confirmed pancreatic ductal adenocarcinoma. Following screening, using a standardized administration prot...

Enrolling
Pancreatic Ductal Adenocarcinoma (PDAC)
Drug: [18F]FAPI-74 PET/CT

Phase 3

SOFIE

Cleveland, Ohio, United States and 9 other locations

with chemotherapy in participants with previously untreated advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma...

Enrolling
Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Drug: Nivolumab
Drug: Pumitamig

Phase 2, Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Cleveland, Ohio, United States and 158 other locations

first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...

Active, not recruiting
Advanced Upper Gastrointestinal Tract Adenocarcinoma
Drug: Domvanalimab
Drug: Zimberelimab

Phase 3

Arcus Biosciences
Arcus Biosciences

Cleveland, Ohio, United States and 212 other locations

This study is open to adults with advanced pancreatic cancer. The study tests a type of immunotherapy. It is a protein treatment combined with a viru...

Active, not recruiting
Pancreatic Ductal Adenocarcinoma
Drug: ATP150
Drug: ATP152

Phase 1

Boehringer Ingelheim
Boehringer Ingelheim

Cleveland, Ohio, United States and 24 other locations

This is an open label Phase 2 study to evaluate the efficacy and safety of ACR-368 as monotherapy or with ultra-low dose gemcitabine (ULDG) sensitiza...

Enrolling
Endometrial Adenocarcinoma
Drug: ACR-368
Drug: Gemcitabine

Phase 2

Acrivon Therapeutics

Cleveland, Ohio, United States and 89 other locations

This trial studies tucatinib to find out if it is safe when given with trastuzumab and other anti-cancer drugs (pembrolizumab, FOLFOX, and CAPOX). It...

Active, not recruiting
Esophageal Adenocarcinoma
Gastric Adenocarcinoma
Drug: oxaliplatin
Drug: trastuzumab

Phase 2

Seagen, a wholly owned subsidiary of Pfizer

Cleveland, Ohio, United States and 26 other locations

A multicenter, single-arm, first-in-human study to investigate the safety, pharmacokinetics, and preliminary antitumor activity of PLX-61639 in parti...

Enrolling
Gastroesophageal Junction (GEJ) Adenocarcinoma
Esophageal Adenocarcinoma
Drug: PLX-61639

Phase 1

Plexium, Inc.

Cleveland, Ohio, United States and 9 other locations

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