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The purpose of this study is to characterize the safety, preliminary efficacy, and immune biologic activity of CAN-2409 + prodrug (valacyclovir or ac...
Phase 2
Columbus, Ohio, United States and 2 other locations
This is a single arm phase II study. All patients will receive 3 cycles of the treatment of nab-paclitaxel (Days 1, 8 and 15), gemcitabine (Days 1, 8...
Phase 2
Columbus, Ohio, United States
participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignatur...
Phase 1, Phase 2
Hilliard, Ohio, United States and 66 other locations
first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...
Phase 3
Columbus, Ohio, United States and 203 other locations
mCRPC. Patients enrolled in the Phase 2a portion of the study will have either Small Cell Neuroendocrine Prostate Cancer(SCNC)(Cohort A) or adenocarcinoma...
Phase 1, Phase 2
Columbus, Ohio, United States and 11 other locations
unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma. Why is this study being done? SPOTLIGHT is a new clinical st...
Phase 3
Columbus, Ohio, United States and 219 other locations
A phase IIb, open-label, randomized study of Nab-Paclitaxel and Gemcitabine and plus/minus VCN-01 in Patients with Metastatic Pancreatic Cancer
Phase 2
Columbus, Ohio, United States and 16 other locations
in subjects previously untreated for metastatic pancreatic ductal adenocarcinoma (PDA), including subjects who have received prior neoadjuva...
Phase 2, Phase 3
Columbus, Ohio, United States and 91 other locations
This research is designed to determine if experimental treatment with Antibody-drug conjugate, AZD5335, alone, or in combination with anti-cancer age...
Phase 1, Phase 2
Columbus, Ohio, United States and 48 other locations
The purpose of the dose escalation phase is to evaluate the safety profile of escalating doses and dose schedules of NXP800. In the expansion phase t...
Phase 1
Columbus, Ohio, United States and 21 other locations
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