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The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard of care (SOC) observation only.
Phase 3
Durham, North Carolina, United States and 42 other locations
participants to treat locally advanced unresectable or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma (mGEA).T...
Phase 2
Durham, North Carolina, United States and 48 other locations
This study will help find the most suitable dose of ASP546C in people with gastric cancer, gastroesophageal junction (GEJ) cancer, pancreatic cancer,...
Phase 1, Phase 2
Durham, North Carolina, United States and 13 other locations
The purpose of this study is to combine standard radiation therapy with drugs that encourages the body's immune system against cancer cells and simul...
Phase 2
Chapel Hill, North Carolina, United States and 4 other locations
The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.
Phase 3
Durham, North Carolina, United States and 59 other locations
with chemotherapy in participants with previously untreated advanced or metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma...
Phase 2, Phase 3
Chapel Hill, North Carolina, United States and 161 other locations
first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...
Phase 3
Durham, North Carolina, United States and 174 other locations
T-cells in Subjects with Unresectable, Locally Advanced, or Metastatic Gastric, Gastroesophageal Junction (GEJ), Esophageal, or Pancreatic Adenocarcinoma...
Phase 1
Durham, North Carolina, United States and 8 other locations
newly diagnosed, advanced, unresectable colorectal cancer (CRC) or 2) patients with newly diagnosed, advanced, unresectable pancreatic ductal adenocarcinoma...
Phase 2
Durham, North Carolina, United States and 25 other locations
Zolbetuximab is being studied in people with cancer in and around the stomach or where the food pipe (esophagus) joins the stomach, called gastroesop...
Phase 3
Durham, North Carolina, United States and 248 other locations
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