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Find clinical trials for Adenocarcinoma in Houston, TX

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Adenocarcinoma trials near Houston, TX, USA:

A Study to Evaluate the Adverse Events, Efficacy, and Optimal Dose of Intravenous (IV) ABBV-400 in Combination With IV Fluorouracil, Leucovorin, and Budigalimab in Adult Participants With Locally Advanced Unresectable or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (AndroMETa-GEA)

metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma (mGEA).ABBV-400 and Budigalimab are investigational drugs being...

Enrolling
Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma
Esophageal Adenocarcinoma
Drug: Budigalimab
Drug: ABBV-400

Phase 2

AbbVie
AbbVie

Houston, Texas, United States and 11 other locations

to evaluate the safety and efficacy of first-line chemo-immunotherapy combinations in participants with metastatic pancreatic ductal adenocarcinoma...

Active, not recruiting
Metastatic Pancreatic Adenocarcinoma
Drug: NG350A (Cohort C)
Drug: Nab-paclitaxel (nP) (Cohort A, B and C)

Phase 1

Cancer Insight

Houston, Texas, United States and 5 other locations

The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...

Enrolling
Metastatic Pancreatic Ductal Adenocarcinoma
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 3

Arcus Biosciences
Arcus Biosciences

Houston, Texas, United States and 82 other locations

cancer Trial Phase: Phase II Clinical Indication: Pancreatic ductal adenocarcinoma; Adenocarcinoma; AJCC I, II, or III; 1st Line ne...

Enrolling
Pancreatic Ductal Adenocarcinoma
Drug: Pembrolizumab
Drug: Folfirinox

Phase 2

Baylor College of Medicine
Baylor College of Medicine

Houston, Texas, United States and 2 other locations

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.

Enrolling
PDAC - Pancreatic Ductal Adenocarcinoma
PDAC
Drug: 5-fluorouracil
Drug: leucovorin

Phase 3

Revolution Medicines
Revolution Medicines

Houston, Texas, United States and 38 other locations

Recently updated

esophageal adenocarcinoma.This substudy will have two phases: a safety lead-in phase and an efficacy phase. The safety lead-in phase will b...

Enrolling
Gastroesophageal Adenocarcinoma
Esophageal Cancer
Drug: Levoleucovorin
Drug: Capecitabine

Phase 1, Phase 2

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Houston, Texas, United States and 37 other locations

This study is an open-label, phase 1/1b study of the pressure-enabled intrapancreatic infusion of SD-101, a TLR 9 agonist, alone or in combination wi...

Enrolling
Locally Advanced Pancreatic Adenocarcinoma
Drug: SD-101
Biological: anti-PD-1

Phase 1

TriSalus Life Sciences

Houston, Texas, United States

and capecitabine monotherapy in patients with metastatic pancreatic adenocarcinoma whose disease has not progressed on a first line fluoropy...

Enrolling
Metastatic Pancreatic Adenocarcinoma
Drug: Capecitabine
Drug: Ivaltinostat

Phase 1, Phase 2

CG Pharmaceuticals

Houston, Texas, United States and 15 other locations

as First-Line or Second-Line Therapy in Adult Patients with Inoperable, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma...

Active, not recruiting
Gastric Adenocarcinoma
Gastric Cancer
Drug: Tislelizumab 200mg
Drug: DKN-01 400mg

Phase 2

Leap Therapeutics

Houston, Texas, United States and 47 other locations

adenocarcinoma (GEA), biliary tract cancer (BTC), or colorectal cancer (CRC)....

Active, not recruiting
HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer
Drug: Oxaliplatin
Drug: Fluorouracil

Phase 2

Jazz Pharmaceuticals
Jazz Pharmaceuticals

Houston, Texas, United States and 22 other locations

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