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Find clinical trials for Adenocarcinoma in Philadelphia, PA

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Related conditions:

Pancreatic Cancer
Non-Small-Cell Lung Carcinoma
Colorectal Cancer
Stomach Cancer
Esophageal Cancer
Cancer
Carcinoma

Adenocarcinoma trials near Philadelphia, PA, USA:

Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma

The research study is being conducted to study whether performing injections of a new treatment, called RP2, directly into stomach and esophagus tumo...

Begins enrollment this month
Esophageal Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Procedure: Surgical Resection of Primary Tumor
Drug: Filgrastim

Phase 2

Abramson Cancer Center at Penn Medicine
Abramson Cancer Center at Penn Medicine

Philadelphia, Pennsylvania, United States

to evaluate the safety and efficacy of first-line chemo-immunotherapy combinations in participants with metastatic pancreatic ductal adenocarcinoma...

Active, not recruiting
Metastatic Pancreatic Adenocarcinoma
Drug: NG350A (Cohort C)
Drug: Nab-paclitaxel (nP) (Cohort A, B and C)

Phase 1

Cancer Insight

Philadelphia, Pennsylvania, United States and 5 other locations

This study will evaluate the safety and effectiveness of the combination of pembrolizumab and odetiglucan in patients with metastatic colorectal canc...

Enrolling
Colorectal Adenocarcinoma Metastatic in the Liver
Drug: Odetiglucan
Drug: Pembrolizumab

Phase 2

Abramson Cancer Center at Penn Medicine
Abramson Cancer Center at Penn Medicine

Philadelphia, Pennsylvania, United States

resectable gastric, gastroesophageal junction (GEJ), or esophageal adenocarcinoma who have not received previous treatment for the disease....

Enrolling
Gastroesophageal Adenocarcinoma
Drug: Rilvegostomig
Drug: 5-Fluorouracil (5-FU)

Phase 2

AstraZeneca
AstraZeneca

Newark, Delaware, United States and 63 other locations

The purpose of this study is to compare overall survival of quemliclustat, nab-paclitaxel and gemcitabine versus placebo, nab-paclitaxel and gemcitab...

Active, not recruiting
Metastatic Pancreatic Ductal Adenocarcinoma
Drug: Gemcitabine
Drug: Nab-paclitaxel

Phase 3

Arcus Biosciences
Arcus Biosciences

Philadelphia, Pennsylvania, United States of America and 124 other locations

The purpose of this study is to test any good and bad effects of the study drug called PEGPH20. PEGPH20 alone is considered investigational. The Food...

Active, not recruiting
Advanced Pancreatic Ductal Adenocarcinoma
Pancreatic Cancer
Drug: Nab-paclitaxel
Drug: Gemcitabine
Memorial Sloan Kettering Cancer Center (MSK)
Memorial Sloan Kettering Cancer Center (MSK)

Allentown, Pennsylvania, United States and 9 other locations

The goal of this clinical trial is to determine clinical advantages for LP-300 in combination with carboplatin and pemetrexed in the never smoker pat...

Enrolling
Adenocarcinoma of Lung
Carcinoma, Non-Small-Cell Lung
Drug: Pemetrexed
Drug: Carboplatin

Phase 2

Lantern Pharma

Philadelphia, Pennsylvania, United States of America and 16 other locations

The purpose of this study is to combine standard radiation therapy with drugs that encourages the body's immune system against cancer cells and simul...

Enrolling
Pancreatic Ductal Adenocarcinoma
Drug: Zimberelimab
Drug: Modified FOLFIRINOX

Phase 2

Gulam Manji

Philadelphia, Pennsylvania, United States and 4 other locations

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to standard(s) of care (SOC) treatment.

Enrolling
PDAC - Pancreatic Ductal Adenocarcinoma
PDAC
Drug: 5-fluorouracil
Drug: leucovorin

Phase 3

Revolution Medicines
Revolution Medicines

Philadelphia, Pennsylvania, United States and 59 other locations

This is a Phase 1a, open label, single dose, extended study of safety and biokinetics of RAD301 in healthy human volunteers and individuals with PDAC.

Enrolling
Pancreatic Ductal Adenocarcinoma
Healthy Volunteers
Drug: RAD301 ([68Ga]-RAD301)

Phase 1

Radiopharm Theranostics

Princeton, New Jersey, United States and 1 other location

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