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Find clinical trials for Adenocarcinoma in Philadelphia, PA

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Related conditions:

Carcinoma
Cancer
Pancreatic Cancer
Colorectal Cancer
Stomach Cancer
Prostatic Cancer
Esophageal Cancer

Adenocarcinoma trials near Philadelphia, PA, USA:

Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel (PANOVA-3)

for front line treatment of locally-advanced pancreatic adenocarcinoma.The device is an experimental, portable, battery operated device for ...

Active, not recruiting
Pancreas Adenocarcinoma
Drug: Gemcitabine
Drug: nab paclitaxel

Phase 3

NovoCure
NovoCure

Fountain Hill, Pennsylvania, United States and 197 other locations

to evaluate the safety and efficacy of first-line chemo-immunotherapy combinations in participants with metastatic pancreatic ductal adenocarcinoma...

Active, not recruiting
Metastatic Pancreatic Adenocarcinoma
Drug: Nab-paclitaxel (nP) (Cohort A, B and C)
Drug: Gemcitabine (gem) (Cohort A, B and C)

Phase 1

Cancer Insight

Philadelphia, Pennsylvania, United States and 5 other locations

The main purpose of this study is to look at the effectiveness, safety, and anti-tumor activity (preventing growth of the tumor) of the drugs Nirapar...

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Niraparib + Ipilimumab
Drug: Niraparib + Nivolumab

Phase 1, Phase 2

University of Pennsylvania
University of Pennsylvania

Philadelphia, Pennsylvania, United States

The purpose of this study is to test any good and bad effects of the study drug called PEGPH20. PEGPH20 alone is considered investigational. The Food...

Active, not recruiting
Advanced Pancreatic Ductal Adenocarcinoma
Pancreatic Cancer
Drug: PEGPH20
Drug: Gemcitabine
Memorial Sloan Kettering Cancer Center (MSK)
Memorial Sloan Kettering Cancer Center (MSK)

Allentown, Pennsylvania, United States and 9 other locations

The goal of this clinical trial is to determine clinical advantages for LP-300 in combination with carboplatin and pemetrexed in the never smoker pat...

Enrolling
Adenocarcinoma of Lung
Carcinoma, Non-Small-Cell Lung
Drug: Pemetrexed
Drug: Carboplatin

Phase 2

Lantern Pharma

Philadelphia, Pennsylvania, United States of America and 9 other locations

as First-Line or Second-Line Therapy in Adult Patients with Inoperable, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma...

Active, not recruiting
Gastric Adenocarcinoma
Gastric Cancer
Drug: Capecitabine 1000mg/ m2 BID
Drug: DKN-01 600mg

Phase 2

Leap Therapeutics

Philadelphia, Pennsylvania, United States of America and 47 other locations

participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignatur...

Enrolling
Endometrial Adenocarcinoma
Urothelial Carcinoma
Drug: ACR-368
Diagnostic Test: OncoSignature

Phase 1, Phase 2

Acrivon Therapeutics

Philadelphia, Pennsylvania, United States of America and 67 other locations

adenocarcinoma (GEA), biliary tract cancer (BTC), or colorectal cancer (CRC)....

Active, not recruiting
HER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal Cancer
Drug: Oxaliplatin
Drug: Fluorouracil

Phase 2

Jazz Pharmaceuticals
Jazz Pharmaceuticals

Philadelphia, Pennsylvania, United States of America and 20 other locations

and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma...

Enrolling
Gastroesophageal Junction Cancer
Gastric Cancer
Drug: Apatinib
Drug: Ramucirumab+ paclitaxel

Phase 3

AstraZeneca
AstraZeneca

Philadelphia, Pennsylvania, United States and 149 other locations

This study is being done to see if tucatinib with trastuzumab, ramucirumab and paclitaxel works better than ramucirumab and paclitaxel to treat HER2-...

Active, not recruiting
Esophageal Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Drug: paclitaxel
Drug: trastuzumab

Phase 2, Phase 3

Seagen
Seagen

Philadelphia, Pennsylvania, United States and 47 other locations

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