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(TPC) in participants with advanced/metastatic gastroesophageal adenocarcinoma. The primary hypothesis of this study is sacituzumab tirumote...
Phase 3
Pittsburgh, Pennsylvania, United States and 113 other locations
and immunogenicity of novel combination therapies in participants with locally advanced unresectable or metastatic gastric or GEJ adenocarcinoma...
Phase 2
Pittsburgh, Pennsylvania, United States and 42 other locations
combinations in participants with metastatic Pancreatic Ductal Adenocarcinoma (PDAC).Two cohorts will be enrolled in parallel in this study:...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 26 other locations
This trial examines how Pancreatic Adenocarcinoma reacts to the addition of 9-ING-41 and retifanlimab to the standard of care chemotherapy t...
Phase 2
Pittsburgh, Pennsylvania, United States and 1 other location
will be eligible for screening: unresectable or metastatic gastric adenocarcinoma, gastroesophageal junction (GEJ) adenocarcinoma, ...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 5 other locations
participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignatur...
Phase 1, Phase 2
Pittsburgh, Pennsylvania, United States and 66 other locations
after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponso...
Phase 3
Pittsburgh, Pennsylvania, United States and 195 other locations
The study will compare the efficacy and safety of pembrolizumab plus trastuzumab in combination with standard of care (SOC) chemotherapy versus trast...
Phase 3
Pittsburgh, Pennsylvania, United States and 191 other locations
The purpose of this study is to assess the efficacy and safety of lenvatinib (E7080/MK-7902) plus pembrolizumab (MK-3475) plus chemotherapy compared...
Phase 3
Pittsburgh, Pennsylvania, United States and 176 other locations
Phase I Study of NT-112, an autologous T-cell therapy product genetically engineered to express an HLA-C\*08:02-restricted T cell receptor (TCR), tar...
Phase 1
Pittsburgh, Pennsylvania, United States and 11 other locations
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