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Find clinical trials for Adenocarcinoma in Pittsburgh, PA

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Related conditions:

Carcinoma
Cancer
Pancreatic Cancer
Colorectal Cancer
Stomach Cancer
Prostatic Cancer
Esophageal Cancer

Adenocarcinoma trials near Pittsburgh, PA, USA:

Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

and immunogenicity of novel combination therapies in participants with locally advanced unresectable or metastatic gastric or GEJ adenocarcinoma...

Enrolling
Gastric Cancer
Drug: 5-Fluorouracil
Drug: AZD0901

Phase 2

AstraZeneca
AstraZeneca

Pittsburgh, Pennsylvania, United States and 42 other locations

combinations in participants with metastatic Pancreatic Ductal Adenocarcinoma (PDAC).Two cohorts will be enrolled in parallel in this study:...

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Fluorouracil
Drug: RO6874281

Phase 1, Phase 2

Roche
Roche

Pittsburgh, Pennsylvania, United States and 26 other locations

This trial examines how Pancreatic Adenocarcinoma reacts to the addition of 9-ING-41 and retifanlimab to the standard of care chemotherapy t...

Active, not recruiting
Pancreatic Adenocarcinoma
Drug: Gemcitabine
Drug: 9-ING-41

Phase 2

Anwaar Saeed

Pittsburgh, Pennsylvania, United States and 1 other location

participants with platinum-resistant ovarian carcinoma, endometrial adenocarcinoma, and urothelial carcinoma based on Acrivon's OncoSignatur...

Enrolling
Endometrial Adenocarcinoma
Urothelial Carcinoma
Drug: ACR-368
Diagnostic Test: OncoSignature

Phase 1, Phase 2

Acrivon Therapeutics

Pittsburgh, Pennsylvania, United States and 67 other locations

This study is being done to see if tucatinib with trastuzumab, ramucirumab and paclitaxel works better than ramucirumab and paclitaxel to treat HER2-...

Active, not recruiting
Esophageal Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Drug: paclitaxel
Drug: trastuzumab

Phase 2, Phase 3

Seagen
Seagen

Pittsburgh, Pennsylvania, United States and 47 other locations

The study will compare the efficacy and safety of pembrolizumab plus trastuzumab in combination with standard of care (SOC) chemotherapy versus trast...

Active, not recruiting
Gastroesophageal Junction Adenocarcinoma
Gastric Neoplasms
Drug: Oxaliplatin
Drug: Cisplatin

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Pittsburgh, Pennsylvania, United States and 191 other locations

The purpose of this study is to assess the efficacy and safety of lenvatinib (E7080/MK-7902) plus pembrolizumab (MK-3475) plus chemotherapy compared...

Active, not recruiting
Advanced/Metastatic Gastroesophageal Adenocarcinoma
Drug: Oxaliplatin
Biological: Lenvatinib

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Pittsburgh, Pennsylvania, United States and 176 other locations

GEJ adenocarcinoma in adult participants.The primary hypotheses of this study are that pembrolizumab plus chemotherapy is superior to place...

Active, not recruiting
Stomach Neoplasms
Drug: capecitabine
Drug: Cisplatin

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Pittsburgh, Pennsylvania, United States and 214 other locations

The purpose of this study is to look at the efficacy and safety of Irinotecan liposome injection in combination with other approved drugs used for ca...

Active, not recruiting
Metastatic Adenocarcinoma of the Pancreas
Drug: Leucovorin
Drug: Gemcitabine

Phase 3

Ipsen
Ipsen

Pittsburgh, Pennsylvania, United States and 199 other locations

This is a first-in-human, open-label, multi-center, Phase 1, dose-escalation study with expansion cohorts to evaluate NM32-2668 for safety and immuno...

Enrolling
Adenocarcinoma - Gastroesophageal Junction (GEJ)
Adenocarcinoma of the Stomach
Biological: NM32-2668

Phase 1

Numab Therapeutics

Pittsburgh, Pennsylvania, United States and 4 other locations

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