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Find clinical trials for Adenocarcinoma in St Louis, MO

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Carcinoma
Cancer
Pancreatic Cancer
Colorectal Cancer
Stomach Cancer
Prostatic Cancer
Esophageal Cancer

Adenocarcinoma trials near St Louis, MO, USA:

Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma

Patients with advanced pancreas adenocarcinoma will be randomized on a 6:1 basis to receive standard of care chemotherapy followed by stereo...

Enrolling
Pancreas Adenocarcinoma
Pancreas Cancer
Device: MR-guided stereotactic body radiation therapy
Procedure: Tumor biopsy

Phase 2

The Washington University
The Washington University

Saint Louis, Missouri, United States

The purpose of this research study is to learn more about a new combination of drugs being given to treat pancreatic cancer. The drugs being tested a...

Active, not recruiting
Pancreatic Ductal Adenocarcinoma
Drug: BMS-813160
Drug: Gemcitabine

Phase 1, Phase 2

The Washington University
The Washington University

Saint Louis, Missouri, United States

This is a Phase 1 study to assess the safety and efficacy of ELI-002 immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide [Amph-CpG-7...

Active, not recruiting
Pancreatic Ductal Adenocarcinoma
NRAS G12D
Drug: ELI-002 2P

Phase 1

Elicio Therapeutics
Elicio Therapeutics

Saint Louis, Missouri, United States and 9 other locations

The purpose of this study is to confirm the recommended phase 2 dose (RP2D) of zolbetuximab in combination with Nab-P + GEM, determine overall surviv...

Enrolling
Metastatic Pancreatic Adenocarcinoma
Metastatic Pancreatic Cancer
Drug: gemcitabine
Drug: nab-paclitaxel

Phase 2

Astellas
Astellas

Creve Coeur, Missouri, United States and 182 other locations

and safety of AZD0901 compared to Investigator's choice of therapy as 2L+ treatment for participants with advanced or metastatic gastric or GEJ adenocarcinoma...

Enrolling
Gastroesophageal Junction Cancer
Gastric Cancer
Drug: Apatinib
Drug: Ramucirumab+ paclitaxel

Phase 3

AstraZeneca
AstraZeneca

Saint Louis, Missouri, United States and 118 other locations

The study will compare the efficacy and safety of pembrolizumab plus trastuzumab in combination with standard of care (SOC) chemotherapy versus trast...

Active, not recruiting
Gastroesophageal Junction Adenocarcinoma
Gastric Neoplasms
Drug: Oxaliplatin
Drug: Cisplatin

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Saint Louis, Missouri, United States and 191 other locations

The purpose of this study is to assess the efficacy and safety of lenvatinib (E7080/MK-7902) plus pembrolizumab (MK-3475) plus chemotherapy compared...

Active, not recruiting
Advanced/Metastatic Gastroesophageal Adenocarcinoma
Drug: Oxaliplatin
Biological: Lenvatinib

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Saint Louis, Missouri, United States and 176 other locations

Barrett's Esophagus (BE), with or without dysplasia, and esophageal adenocarcinoma (EAC) as compared to Esophagogastroduodenoscopy (EGD) plu...

Enrolling
Esophageal Adenocarcinoma
Barretts Esophagus With Dysplasia
Diagnostic Test: Esophagogastroduodenoscopy
Device: EsoGuard (lab assay)
Lucid Diagnostics

Saint Louis, Missouri, United States and 37 other locations

and efficacy of avutometinib (VS-6766) and defactinib in combination with gemcitabine and nab-paclitaxel in patients with Pancreatic Ductal Adenocarcinoma...

Enrolling
Metastatic Cancer
KRAS Activating Mutation
Drug: avutometinib (VS-6766) and defactinib in combination with gemcitabine and nab-paclitaxel

Phase 1, Phase 2

Verastem

Saint Louis, Missouri, United States and 10 other locations

This is a randomized phase II study examining nivolumab alone versus radiation therapy with nivolumab in subjects who did not have disease progressio...

Active, not recruiting
Gastroesophageal Adenocarcinoma
Drug: Nivolumab 240 MG

Phase 2

Weill Cornell Medicine (WCM)
Weill Cornell Medicine (WCM)

Saint Louis, Missouri, United States and 4 other locations

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