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The purpose of the study is to determine the feasibility of using magnetic resonance imaging (MRI)-guided adaptive chemoradiation therapy to improve...
Early Phase 1
Tampa, Florida, United States
The study is designed to assess whether glufosfamide provides additional survival benefit as compared to bolus 5-FU in patients with metastatic pancr...
Phase 3
Tampa, Florida, United States and 2 other locations
adenocarcinoma (GEA), biliary tract cancer (BTC), or colorectal cancer (CRC)....
Phase 2
Tampa, Florida, United States and 20 other locations
first-line treatment of participants with locally advanced unresectable or metastatic gastric, gastroesophageal junction (GEJ), and esophageal adenocarcinoma...
Phase 3
Saint Petersburg, Florida, United States and 203 other locations
mCRPC. Patients enrolled in the Phase 2a portion of the study will have either Small Cell Neuroendocrine Prostate Cancer(SCNC)(Cohort A) or adenocarcinoma...
Phase 1, Phase 2
Tampa, Florida, United States and 11 other locations
after complete surgical resection (R0) in participants with Stage I adenocarcinoma NSCLC who are ctDNA-positive, as determined by the Sponso...
Phase 3
Saint Petersburg, Florida, United States and 186 other locations
This research study is studying a combination of hormonal therapy, chemotherapy, and immunotherapy as a possible treatment for metastatic hormone-sen...
Phase 2
Tampa, Florida, United States and 5 other locations
Subjects will be offered the opportunity to participate in a randomized, controlled, 2-arm, unblinded multicenter trial (RCT). There will be 2 study...
Phase 3
Tampa, Florida, United States and 5 other locations
This is a nonrandomized, uncontrolled, open-label, multicenter Phase 2 study to evaluate the efficacy, safety, and tolerability of futibatinib in com...
Phase 2
Tampa, Florida, United States and 21 other locations
The purpose of the dose escalation phase is to evaluate the safety profile of escalating doses and dose schedules of NXP800. In the expansion phase t...
Phase 1
St. Petersburg, Florida, United States and 21 other locations
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