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Find clinical trials for Alzheimer's Disease in Nashville, TN

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Psychomotor Agitation
Brain Diseases
Neurodegenerative Diseases

Alzheimer's Disease trials near Nashville, TN, USA:

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

and pharmacodynamic effects of ACI-24.060 in subjects with prodromal Alzheimer's disease and in non-demented adults with Down syndr...

Enrolling
Prodromal Alzheimer's Disease
Alzheimer's Disease
Biological: Placebo
Biological: ACI-24.060 at Dose D

Phase 1, Phase 2

AC Immune

Nashville, Tennessee, United States and 18 other locations

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Enrolling
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Nashville, Tennessee, United States and 117 other locations

The purpose of this study is to evaluate the safety and efficacy of KarXT in adult participants with mild to severe Alzheimer's Disease...

Enrolling
Alzheimer Disease
Drug: Placebo
Drug: KarXT

Phase 3

Karuna Therapeutics
Karuna Therapeutics

Nashville, Tennessee, United States and 136 other locations

This project will investigate the potential of Deep Brain Stimulation to improve cognitive abilities and counteract the effects of Alzheimer's...

Begins enrollment in 1 month
Alzheimer Disease
Alzheimer Disease, Early Onset
Device: DBS Stimulation - Boston Scientific, VERCISE GENUS™ system
Procedure: Device Implantation- Boston Scientific, VERCISE GENUS™ system
Vanderbilt University Medical Center
Vanderbilt University Medical Center

Nashville, Tennessee, United States

study is to assess the effectiveness, safety, and tolerability of BMS-986446 an Anti-MTBR Tau Monoclonal Antibody in participants with Early Alzheimer's...

Enrolling
Alzheimer Disease, Early Onset
Other: Placebo
Drug: BMS-986446

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Nashville, Tennessee, United States and 203 other locations

outpatient study in subjects with psychosis associated with Alzheimer's Disease.The primary objective of the study is to evaluate r ...

Enrolling
Psychosis Associated With Alzheimer's Disease
Drug: Placebo
Drug: KarXT

Phase 3

Karuna Therapeutics
Karuna Therapeutics

Franklin, Tennessee, United States of America and 106 other locations

A 76-week safety and efficacy study of simufilam (PTI-125) given twice daily to participants with mild-to-moderate Alzheimer's disease...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: Simufilam

Phase 3

Cassava Sciences

Franklin, Tennessee, United States of America and 89 other locations

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.Participants w...

Active, not recruiting
Early Alzheimer's Disease
Drug: Placebo (semaglutide)
Drug: Semagludtide

Phase 3

Novo Nordisk
Novo Nordisk

Nashville, Tennessee, United States and 341 other locations

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.Participants w...

Active, not recruiting
Early Alzheimer´s Disease
Drug: Placebo (semaglutide)
Drug: Semaglutide

Phase 3

Novo Nordisk
Novo Nordisk

Nashville, Tennessee, United States and 381 other locations

Investigators propose a phase 1b/2a, randomized, double-blind, placebo-controlled, parallel group dose finding and biomarker study to evaluate the sa...

Not yet enrolling
Alzheimer Disease
Mild Cognitive Impairment
Drug: 2-hydroxybenzylamine acetate
Other: Placebo

Phase 1, Phase 2

MTI Biotech Inc

Nashville, Tennessee, United States

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