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Find clinical trials for Alzheimer's Disease in Nashville, TN

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Related conditions:

Alzheimer Disease
Dementia
Cognitive Dysfunction
Mental Disorders
Brain Diseases
Neurodegenerative Diseases
Psychomotor Agitation

Alzheimer's Disease trials near Nashville, TN, USA:

AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid

is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Tri...

Enrolling
Preclinical Alzheimer's Disease
Early Preclinical Alzheimer's Disease
Drug: Lecanemab
Drug: Placebo

Phase 3

Eisai
Eisai

Nashville, Tennessee, United States and 111 other locations

Alzheimer's disease (AD) is a progressive, irreversible neurological disorder and is the most common cause of dementia in the elder...

Enrolling
Alzheimer's Disease (AD)
Drug: ABBV-552
Drug: Placebo for ABBV-552

Phase 2

AbbVie
AbbVie

Nashville, Tennessee, United States and 63 other locations

study is to assess the effectiveness, safety, and tolerability of BMS-986446 an Anti-MTBR Tau Monoclonal Antibody in participants with Early Alzheimer's...

Enrolling
Alzheimer Disease, Early Onset
Other: Placebo
Drug: BMS-986446

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Franklin, Tennessee, United States and 183 other locations

outpatient study in subjects with psychosis associated with Alzheimer's Disease.The primary objective of the study is to evaluate r ...

Enrolling
Psychosis Associated With Alzheimer's Disease
Drug: KarXT
Drug: Placebo

Phase 3

Karuna Therapeutics
Karuna Therapeutics

Franklin, Tennessee, United States and 76 other locations

A 76-week safety and efficacy study of simufilam (PTI-125) given twice daily to participants with mild-to-moderate Alzheimer's disease...

Active, not recruiting
Alzheimer Disease
Drug: Placebo
Drug: Simufilam

Phase 3

Cassava Sciences

Franklin, Tennessee, United States and 89 other locations

This project will investigate the potential of Deep Brain Stimulation to improve cognitive abilities and counteract the effects of Alzheimer's...

Begins enrollment in 8 months
Alzheimer Disease
Alzheimer Disease, Early Onset
Device: DBS Stimulation - Boston Scientific, VERCISE GENUS™ system
Procedure: Device Implantation- Boston Scientific, VERCISE GENUS™ system
Vanderbilt University Medical Center
Vanderbilt University Medical Center

Nashville, Tennessee, United States

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.Participants w...

Active, not recruiting
Early Alzheimer's Disease
Drug: Semagludtide
Drug: Placebo (semaglutide)

Phase 3

Novo Nordisk
Novo Nordisk

Nashville, Tennessee, United States and 343 other locations

This study is done to find out whether the medicine, semaglutide, has a positive effect on early Alzheimer's disease.Participants w...

Active, not recruiting
Early Alzheimer´s Disease
Drug: Semaglutide
Drug: Placebo (semaglutide)

Phase 3

Novo Nordisk
Novo Nordisk

Nashville, Tennessee, United States and 382 other locations

Locations recently updated

This study is being conducted to evaluate the safety and efficacy of ALZ-801 in Early Alzheimer's disease (AD) subjects with the AP...

Active, not recruiting
Early Alzheimer's Disease
Drug: Experimental: ALZ-801
Drug: Placebo Comparator: Placebo

Phase 3

Alzheon

Nashville, Tennessee, United States and 94 other locations

This is an extension study of the Phase 3 Studies 15-AVP-786-301, 15-AVP-786-302, and 17-AVP-786-305, which also allows participants from the Phase 2...

Enrolling
Agitation in Patients With Dementia of the Alzheimer's Type
Drug: AVP-786

Phase 3

Otsuka
Otsuka

Franklin, Tennessee, United States and 274 other locations

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