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The purpose of this study is to test the safety and tolerability of PMD-026 in patients with metastatic breast cancer. PMD-026 is a ...
Phase 1, Phase 2
Farmington Hills, Michigan, United States and 7 other locations
The purpose of this study is to assess safety and tolerability of AZD2014 when given in combination with Fulvestrant
Phase 1
Detroit, Michigan, United States and 4 other locations
A phase 1b study to assess the combination of ARV-471 and everolimus in participants with advanced or metastatic ER+/HER2- breast cancer...
Phase 1
Ann Arbor, Michigan, United States and 8 other locations
growth factor receptor-2 negative (HER2-) advanced/metastatic breast cancer who received no prior cyclin-dependent kinase targeting...
Phase 2
Toledo, Ohio, United States and 33 other locations
The Phase 2 part of the trial will evaluate the efficacy and safety of the various combinations in patients with ER+/HER2- advanced/metastatic breast...
Phase 1, Phase 2
Detroit, Michigan, United States of America and 115 other locations
to anti-HER2-based therapy plus endocrine therapy alone in improving the outcomes of subjects with hormone receptor-positive, HER2+ metastatic breast...
Phase 3
Ann Arbor, Michigan, United States and 117 other locations
with pathology-confirmed HR-positive/HER2-negative metastatic breast cancer (MBC) following progression on or after at least two pr...
Phase 2
Maumee, Ohio, United States and 21 other locations
This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...
Phase 3
Detroit, Michigan, United States and 226 other locations
positive (HR+) and human epidermal growth factor 2 negative (HER2-) breast cancer (BC) and other advanced solid tumors. Th...
Phase 1
Detroit, Michigan, United States and 64 other locations
ARV-471 (PF-07850327) given together with palbociclib in advanced breast cancer. In particular, the study will compare the combinat ...
Phase 3
Ann Arbor, Michigan, United States and 39 other locations
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