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A randomized, Phase II trial of circulating tumor DNA-guided second line Adjuvant therapy for high Residual risk, Estrogen Receptor positive ...
Phase 2
Aurora, Colorado, United States and 14 other locations
growth factor receptor-2 negative (HER2-) advanced/metastatic breast cancer who received no prior cyclin-dependent kinase targeting...
Phase 2
Aurora, Colorado, United States and 33 other locations
A Phase 1 Dose Escalation and Expansion Study of AZD9833 Alone or in Combination in Women with ER Positive, HER2 Negative Advanced Breast Ca...
Phase 1
Aurora, Colorado, United States and 16 other locations
together. A side effect is anything a drug does besides treating cancer.Participants in this trial have HER2-positive (HER2+) breast...
Phase 2
Aurora, Colorado, United States and 32 other locations
The Phase 2 part of the trial will evaluate the efficacy and safety of the various combinations in patients with ER+/HER2- advanced/metastatic breast...
Phase 1, Phase 2
Lone Tree, Colorado, United States and 115 other locations
This study to learn more about olaparib and olaparib plus durvalumab combination therapy and also to better understand the studied disease, breast...
Phase 2
Loveland, Colorado, United States and 36 other locations
endocrine therapy in participants with node-positive, Estrogen Receptor-positive (ER+), Human Epidermal Growth Factor-2 negative (HER2-) early breast...
Phase 3
Lone Tree, Colorado, United States and 44 other locations
Phase IB/II clinical trial of Alpelisb and Tucatinib in patients with PIK3CA-Mutant HER2-positive metastatic breast cancer....
Phase 1, Phase 2
Aurora, Colorado, United States and 3 other locations
postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer with an acquired ESR1 mutation and who have diseas...
Phase 2
Longmont, Colorado, United States and 50 other locations
with pathology-confirmed HR-positive/HER2-negative metastatic breast cancer (MBC) following progression on or after at least two pr...
Phase 2
Aurora, Colorado, United States and 25 other locations
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