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Assess response to pembrolizumab in both primary tumor, normal breast stroma, circulating lymphocytes and serum exosomes in treatment naive ...
Phase 1
Maywood, Illinois, United States and 2 other locations
This research study is for patients with metastatic breast cancer.Metastatic means that the cancer has spread beyond the b...
Phase 2
Chicago, Illinois, United States and 19 other locations
This research is to evaluate the effectiveness of Talazoparib as a potential treatment for metastatic breast cancer with a BRCA 1 o...
Phase 2
Chicago, Illinois, United States and 4 other locations
This is a randomized trial for patients with metastatic hormone receptor (HR)-positive human epidermal growth factor receptor 2 (HER2)-negative breast...
Phase 2
Chicago, Illinois, United States and 12 other locations
This clinical trial will assess the safety and early efficacy of Hydroxychloroquine or Avelumab, with or without Palbociclib, in early-stage ER+ breast...
Phase 2
Chicago, Illinois, United States and 6 other locations
This research study is studying a combination of drugs as a possible treatment for breast cancer.The drugs involved in this study a...
Phase 2
Chicago, Illinois, United States and 16 other locations
This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...
Phase 3
Maywood, Illinois, United States and 226 other locations
A Global, Phase 2 Study of ARX788 in HER2-positive Metastatic Breast Cancer Patients who were previously treated with T-DXd...
Phase 2
Chicago, Illinois, United States and 57 other locations
participants with metastatic or locally advanced Hormone Receptor (HR) positive and Human Epidermal Growth Factor Receptor (HER)2-negative breast...
Phase 1, Phase 2
Chicago, Illinois, United States and 26 other locations
to anti-HER2-based therapy plus endocrine therapy alone in improving the outcomes of subjects with hormone receptor-positive, HER2+ metastatic breast...
Phase 3
Chicago, Illinois, United States and 114 other locations
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