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Find clinical trials for Breast Cancer in Cincinnati, OH

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Related conditions:

Triple Negative Breast Cancer
Non-Small-Cell Lung Carcinoma
Neoplasm Metastasis
Cancer
Ovarian Cancer
Colorectal Cancer
Endometrial Cancer

Breast Cancer trials near Cincinnati, OH, USA:

A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer (ADEPT)

therapy as a treatment after surgery for hormone receptor positive breast cancer.The study drugs involved in this study are:* A com...

Active, not recruiting
Breast Cancer
Hormone Receptor Positive Breast Cancer
Drug: ADJUVANT ENDOCRINE THERAPY
Combination Product: Pertuzumab+TRASTUZUMAB

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Cincinnati, Ohio, United States and 31 other locations

The goal of this clinical trial is to assess the efficacy of DB-1303/BNT323 compared with investigator's choice chemotherapy in terms of progression-...

Active, not recruiting
Metastatic Breast Cancer
Drug: Paclitaxel
Drug: Nab-paclitaxel

Phase 3

DualityBio

Cincinnati, Ohio, United States and 257 other locations

This open-label research study is studying (Z)-endoxifen as a possible treatment for pre-menopausal women with ER+/HER2- breast cancer...

Active, not recruiting
Estrogen-receptor-positive Breast Cancer
Breast Neoplasms
Drug: goserelin
Drug: (Z)-endoxifen

Phase 2

Atossa Therapeutics

Edgewood, Kentucky, United States and 13 other locations

This research study involves testing the safety and efficacy of an investigational intervention for patients with triple-negative breast cancer...

Enrolling
Breast Cancer
Triple Negative Breast Cancer
Drug: Pembrolizumab
Drug: Sacituzumab Govitecan

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Cincinnati, Ohio, United States and 14 other locations

versus T-DM1 in HER2-positive, unresectable and/or metastatic breast cancer subjects previously treated with trastuzumab and taxane....

Active, not recruiting
Breast Cancer
Drug: Trastuzumab deruxtecan (T-DXd)
Drug: Ado-trastuzumab emtansine (T-DM1)

Phase 3

Daiichi Sankyo
Daiichi Sankyo

Cincinnati, Ohio, United States and 163 other locations

RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer...

Active, not recruiting
Breast Cancer
Other: Placebo
Drug: Letrozole

Phase 3

National Surgical Adjuvant Breast and Bowel Project Foundation (NSABP)

Cincinnati, Ohio, United States and 805 other locations

with anti-HER2 antibodies in patients with HER2-negative invasive breast cancer who have abnormal HER2 signaling activity determine...

Enrolling
HER2-negative Breast Cancer
Drug: Doxorubicin
Drug: Cyclophosphamide

Phase 2

National Surgical Adjuvant Breast and Bowel Project Foundation (NSABP)

Dayton, Ohio, United States of America and 42 other locations

endocrine therapy in participants with node-positive, Estrogen Receptor-positive (ER+), Human Epidermal Growth Factor-2 negative (HER2-) early breast...

Enrolling
Breast Cancer
Drug: Elacestrant
Drug: Tamoxifen

Phase 3

Stemline Therapeutics
Stemline Therapeutics

Fairfield, Ohio, United States and 561 other locations

ribociclib or abemaciclib with letrozole) in people with breast cancer:* HR-positive (breast cancer cells that ne...

Active, not recruiting
Breast Cancer
Drug: PF-07220060
Drug: letrozole

Phase 3

Pfizer
Pfizer

Cincinnati, Ohio, United States and 462 other locations

This is a Phase III, randomised, open-label, 3-arm, multicentre, international study assessing the efficacy and safety of Dato-DXd with or without du...

Enrolling
Breast Cancer
Drug: Paclitaxel
Drug: Dato-DXd

Phase 3

AstraZeneca
AstraZeneca

Cincinnati, Ohio, United States and 317 other locations

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