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This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...
Phase 3
Cincinnati, Ohio, United States and 226 other locations
This study to learn more about olaparib and olaparib plus durvalumab combination therapy and also to better understand the studied disease, breast...
Phase 2
Cincinnati, Ohio, United States and 61 other locations
postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer with an acquired ESR1 mutation and who have diseas...
Phase 2
Cincinnati, Ohio, United States and 50 other locations
body) and a treatment part. The primary purpose of the study is to see how (Z)-endoxifen works on tumor cell growth by monitoring a cancer...
Phase 2
Edgewood, Kentucky, United States and 8 other locations
for the treatment of participants with metastatic HER2-positive breast cancer who have progressed on, or are intolerant to, previou...
Phase 3
Cincinnati, Ohio, United States of America and 9 other locations
how treatment with Fulvestrant (FASLODEX) or Anastrozole (ARIMIDEX) effects disease progression for women with locally advanced or metastatic breast...
Phase 3
Montgomery, Ohio, United States and 118 other locations
with anti-HER2 antibodies in patients with HER2-negative invasive breast cancer who have abnormal HER2 signaling activity determine...
Phase 2
Dayton, Ohio, United States of America and 42 other locations
This study is designed to compare the anti-tumor activity as well as the safety and efficacy of DS-8201a versus T-DM1 in HER2-positive, unre ...
Phase 3
Cincinnati, Ohio, United States and 163 other locations
of tumor and/or stromal area of infiltrating lymphocytes prior to initiation of standard neoadjuvant chemotherapy. At enrollment, patients ...
Phase 2
Edgewood, Kentucky, United States and 4 other locations
of fulvestrant or an aromatase inhibitor in women and men with breast cancer whose disease has advanced on one endocrine therapy in...
Phase 3
Dayton, Ohio, United States and 173 other locations
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