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Find clinical trials for Breast Cancer in Cincinnati, OH

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Related conditions:

Triple Negative Breast Cancer
Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
Non-Small-Cell Lung Carcinoma
Ovarian Cancer

Breast Cancer trials near Cincinnati, OH, USA:

DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02]

This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...

Active, not recruiting
Breast Cancer
Drug: Trastuzumab
Drug: Trastuzumab deruxtecan

Phase 3

Daiichi Sankyo
Daiichi Sankyo

Cincinnati, Ohio, United States and 226 other locations

This study to learn more about olaparib and olaparib plus durvalumab combination therapy and also to better understand the studied disease, breast...

Active, not recruiting
Breast Cancer
Combination Product: Neoadjuvant combination therapy with olaparib plus durvalumab
Drug: Neoadjuvant Olaparib monotherapy group

Phase 2

AstraZeneca
AstraZeneca

Cincinnati, Ohio, United States and 61 other locations

postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer with an acquired ESR1 mutation and who have diseas...

Active, not recruiting
Locally Advanced or Metastatic Breast Cancer
Drug: Lasofoxifene
Drug: Fulvestrant

Phase 2

Sermonix Pharmaceuticals

Cincinnati, Ohio, United States and 50 other locations

how treatment with Fulvestrant (FASLODEX) or Anastrozole (ARIMIDEX) effects disease progression for women with locally advanced or metastatic breast...

Active, not recruiting
Hormone Receptor Positive Breast Cancer
Drug: faslodex dummy
Drug: arimidex dummy

Phase 3

AstraZeneca
AstraZeneca

Montgomery, Ohio, United States and 118 other locations

This open-label research study is studying (Z)-endoxifen as a possible treatment for pre-menopausal (still having periods) women with ER+/HER2- breast...

Enrolling
Estrogen-receptor-positive Breast Cancer
Breast Neoplasms
Drug: exemestane
Drug: (Z)-endoxifen

Phase 2

Atossa Therapeutics

Edgewood, Kentucky, United States and 7 other locations

The purpose of this study is to determine if enzalutamide given in combination with exemestane is safe and effective in patients with advanced breast...

Active, not recruiting
Breast Cancer
Drug: Enzalutamide
Drug: exemestane

Phase 2

Pfizer
Pfizer

Cincinnati, Ohio, United States of America and 128 other locations

Some human epidermal growth factor receptor 2 (HER-2) breast cancer patients do not respond or become resistant to current treatmen...

Active, not recruiting
Breast Cancer
Drug: DS-8201a

Phase 2

Daiichi Sankyo
Daiichi Sankyo

Cincinnati, Ohio, United States and 98 other locations

versus T-DM1 in HER2-positive, unresectable and/or metastatic breast cancer subjects previously treated with trastuzumab and taxane....

Active, not recruiting
Breast Cancer
Drug: Trastuzumab deruxtecan (T-DXd)
Drug: Ado-trastuzumab emtansine (T-DM1)

Phase 3

Daiichi Sankyo
Daiichi Sankyo

Cincinnati, Ohio, United States and 163 other locations

with anti-HER2 antibodies in patients with HER2-negative invasive breast cancer who have abnormal HER2 signaling activity determine...

Enrolling
HER2-negative Breast Cancer
Drug: Weekly Paclitaxel
Drug: Pertuzumab

Phase 2

National Surgical Adjuvant Breast and Bowel Project Foundation (NSABP)

Dayton, Ohio, United States and 42 other locations

RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer...

Active, not recruiting
Breast Cancer
Drug: Letrozole
Other: Placebo

Phase 3

National Surgical Adjuvant Breast and Bowel Project Foundation (NSABP)

Cincinnati, Ohio, United States and 805 other locations

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