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study drug, Nivolumab as a possible treatment for triple-negative breast cancer that has spread to other parts of the body.The inte...
Phase 2
Columbus, Ohio, United States and 9 other locations
(ICI) on on 3-year Event Free Survival (EFS), in women with residual hormone receptor negative, HER2-negative ("triple negative") resectable breast...
Phase 2
Columbus, Ohio, United States and 3 other locations
This prospective, multicenter, 1:1 randomized, controlled trial is designed to evaluate the safety and effectiveness of the Breast Cancer...
Columbus, Ohio, United States and 25 other locations
The purpose of this study is to test the safety and tolerability of PMD-026 in patients with metastatic breast cancer. PMD-026 is a ...
Phase 1, Phase 2
Columbus, Ohio, United States and 4 other locations
therapy as a treatment after surgery for hormone receptor positive breast cancer.The study drugs involved in this study are:* A com...
Phase 2
Columbus, Ohio, United States and 27 other locations
The purpose of this study is to find out the possible anti-cancer effect of pelareorep in combination with chemotherapy \[paclitaxel\] and a ...
Phase 2
Columbus, Ohio, United States and 17 other locations
A randomized, Phase II trial of circulating tumor DNA-guided second line Adjuvant therapy for high Residual risk, stage II-III, Estrogen Rec ...
Phase 2
Columbus, Ohio, United States and 14 other locations
DESTINY-Breast07 will investigate the safety, tolerability, and anti-tumour activity of trastuzumab deruxtecan (T-DXd) in combination with o ...
Phase 1, Phase 2
Columbus, Ohio, United States and 71 other locations
to anti-HER2-based therapy plus endocrine therapy alone in improving the outcomes of subjects with hormone receptor-positive, HER2+ metastatic breast...
Phase 3
Columbus, Ohio, United States and 117 other locations
postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer with an acquired ESR1 mutation and who have diseas...
Phase 2
Columbus, Ohio, United States and 50 other locations
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