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Find clinical trials for Breast Cancer in Detroit, MI

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Related conditions:

Triple Negative Breast Cancer
Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
Non-Small-Cell Lung Carcinoma
Neoplasm Metastasis

Breast Cancer trials near Detroit, MI, USA:

AZD2014 and Fulvestrant in Patients With ER+ Advanced Metastatic Breast Cancer

The purpose of this study is to assess safety and tolerability of AZD2014 when given in combination with Fulvestrant

Active, not recruiting
Advanced Metastatic Breast Cancer
Drug: AZD2014
Drug: Fulvestrant

Phase 1

AstraZeneca
AstraZeneca

Detroit, Michigan, United States and 4 other locations

A phase 1b study to assess the combination of ARV-471 and everolimus in participants with advanced or metastatic ER+/HER2- breast cancer...

Active, not recruiting
Breast Cancer
Drug: ARV-471 in combination with Everolimus

Phase 1

Arvinas
Arvinas

Ann Arbor, Michigan, United States and 8 other locations

This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...

Active, not recruiting
Breast Cancer
Drug: Trastuzumab
Drug: Trastuzumab deruxtecan

Phase 3

Daiichi Sankyo
Daiichi Sankyo

Detroit, Michigan, United States and 226 other locations

to anti-HER2-based therapy plus endocrine therapy alone in improving the outcomes of subjects with hormone receptor-positive, HER2+ metastatic breast...

Active, not recruiting
Estrogen Receptor Positive Breast Cancer
HER-2 Positive Breast Cancer
Drug: palbociclib
Drug: trastuzumab

Phase 3

Alliance Foundation Trials

Ann Arbor, Michigan, United States and 117 other locations

ARV-471 (PF-07850327) given together with palbociclib in advanced breast cancer. In particular, the study will compare the combinat ...

Active, not recruiting
Breast Cancer
Drug: Letrozole
Drug: ARV-471 (PF-07850327)

Phase 3

Pfizer
Pfizer

Ann Arbor, Michigan, United States and 38 other locations

how treatment with Fulvestrant (FASLODEX) or Anastrozole (ARIMIDEX) effects disease progression for women with locally advanced or metastatic breast...

Active, not recruiting
Hormone Receptor Positive Breast Cancer
Drug: faslodex dummy
Drug: arimidex dummy

Phase 3

AstraZeneca
AstraZeneca

Detroit, Michigan, United States and 118 other locations

Some human epidermal growth factor receptor 2 (HER-2) breast cancer patients do not respond or become resistant to current treatmen...

Active, not recruiting
Breast Cancer
Drug: DS-8201a

Phase 2

Daiichi Sankyo
Daiichi Sankyo

Detroit, Michigan, United States and 98 other locations

mg in postmenopausal women with oestrogen receptor positive advanced breast cancer who have failed on a previous endocrine treatmen...

Active, not recruiting
Breast Cancer
Drug: Fulvestrant

Phase 3

AstraZeneca
AstraZeneca

Detroit, Michigan, United States and 102 other locations

OKI-219-101 is a Phase 1a/1b, open-label, multicenter, dose-escalation study designed to evaluate the safety, tolerability, pharmacokinetics (PK), ph...

Enrolling
Advanced Cancer
Breast Cancer
Drug: Trastuzumab
Drug: Fulvestrant

Phase 1

OnKure

Detroit, Michigan, United States and 8 other locations

in patients with estrogen receptor positive/human epidermal growth factor receptor 2 negative (ER+/HER2-) locally advanced or metastatic breast...

Active, not recruiting
Breast Cancer
Drug: ARV-471
Drug: ARV-471 in combination with palbociclib (IBRANCE®)

Phase 1, Phase 2

Arvinas
Arvinas

Ann Arbor, Michigan, United States and 15 other locations

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