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The purpose of this study is to assess safety and tolerability of AZD2014 when given in combination with Fulvestrant
Phase 1
Detroit, Michigan, United States and 4 other locations
A phase 1b study to assess the combination of ARV-471 and everolimus in participants with advanced or metastatic ER+/HER2- breast cancer...
Phase 1
Ann Arbor, Michigan, United States and 8 other locations
To evaluate the efficacy of cryoablation without lumpectomy and its impact on local and distant recurrence of early stage breast cancer...
Detroit, Michigan, United States and 18 other locations
This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...
Phase 3
Detroit, Michigan, United States and 226 other locations
to anti-HER2-based therapy plus endocrine therapy alone in improving the outcomes of subjects with hormone receptor-positive, HER2+ metastatic breast...
Phase 3
Ann Arbor, Michigan, United States and 114 other locations
ARV-471 (PF-07850327) given together with palbociclib in advanced breast cancer. In particular, the study will compare the combinat ...
Phase 3
Ann Arbor, Michigan, United States and 38 other locations
Some human epidermal growth factor receptor 2 (HER-2) breast cancer patients do not respond or become resistant to current treatmen...
Phase 2
Detroit, Michigan, United States and 98 other locations
mg in postmenopausal women with oestrogen receptor positive advanced breast cancer who have failed on a previous endocrine treatmen...
Phase 3
Detroit, Michigan, United States and 102 other locations
how treatment with Fulvestrant (FASLODEX) or Anastrozole (ARIMIDEX) effects disease progression for women with locally advanced or metastatic breast...
Phase 3
Detroit, Michigan, United States and 118 other locations
in patients with estrogen receptor positive/human epidermal growth factor receptor 2 negative (ER+/HER2-) locally advanced or metastatic breast...
Phase 1, Phase 2
Ann Arbor, Michigan, United States and 15 other locations
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