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Find clinical trials for Breast Cancer in Pittsburgh, PA

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Related conditions:

Triple Negative Breast Cancer
Cancer
Carcinoma
Squamous Cell Carcinoma of Head and Neck
Endometrial Cancer
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Ovarian Cancer

Breast Cancer trials near Pittsburgh, PA, USA:

Olaparib In Metastatic Breast Cancer

This research study is for patients with metastatic breast cancer.* Metastatic means that the cancer has spread beyond the ...

Active, not recruiting
Somatic Mutation Breast Cancer (BRCA1)
Somatic Mutation Breast Cancer (BRCA2)
Drug: Olaparib

Phase 2

Beth Israel Lahey Health
Beth Israel Lahey Health

Pittsburgh, Pennsylvania, United States and 19 other locations

This research study is studying a drug combination of nivolumab and ipilimumab as a possible treatment for hypermutated HER2 negative breast ...

Active, not recruiting
Breast Cancer
Drug: Ipilimumab
Drug: Nivolumab

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Pittsburgh, Pennsylvania, United States and 2 other locations

This study is being done to look at the role of continuing palbociclib treatment in combination with another type of hormonal therapy (fulvestrant) a...

Active, not recruiting
Metastatic Breast Cancer
Drug: Palbociclib
Drug: Fulvestrant

Phase 2

Johns Hopkins Medicine
Johns Hopkins Medicine

Pittsburgh, Pennsylvania, United States and 4 other locations

This study will compare DS 8201a to standard treatment.Participants must have HER2 breast cancer that has been treated before.Their ...

Active, not recruiting
Breast Cancer
Drug: Trastuzumab
Drug: Trastuzumab deruxtecan

Phase 3

Daiichi Sankyo
Daiichi Sankyo

Pittsburgh, Pennsylvania, United States and 226 other locations

together. A side effect is anything a drug does besides treating cancer.Participants in this trial have HER2-positive (HER2+) breast...

Active, not recruiting
HER2 Positive Breast Cancer
Drug: trastuzumab deruxtecan
Drug: tucatinib

Phase 2

Seagen
Seagen

Pittsburgh, Pennsylvania, United States and 32 other locations

This study to learn more about olaparib and olaparib plus durvalumab combination therapy and also to better understand the studied disease, breast...

Active, not recruiting
Breast Cancer
Combination Product: Neoadjuvant combination therapy with olaparib plus durvalumab
Drug: Neoadjuvant Olaparib monotherapy group

Phase 2

AstraZeneca
AstraZeneca

Pittsburgh, Pennsylvania, United States and 61 other locations

postmenopausal women with locally advanced or metastatic ER+/HER2- breast cancer with an acquired ESR1 mutation and who have diseas...

Active, not recruiting
Locally Advanced or Metastatic Breast Cancer
Drug: Lasofoxifene
Drug: Fulvestrant

Phase 2

Sermonix Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 50 other locations

The purpose of this study is to determine how well participants with stage II-III HER2-positive breast cancer respond to pre-operat...

Active, not recruiting
Breast Cancer
Stage II Breast Cancer
Drug: Trastuzumab
Drug: Margetuximab

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Pittsburgh, Pennsylvania, United States and 13 other locations

Some human epidermal growth factor receptor 2 (HER-2) breast cancer patients do not respond or become resistant to current treatmen...

Active, not recruiting
Breast Cancer
Drug: DS-8201a

Phase 2

Daiichi Sankyo
Daiichi Sankyo

Pittsburgh, Pennsylvania, United States and 98 other locations

Newly diagnosed post-menopausal women with clinical stage II-III, HR+HER2- breast cancer are eligible to a randomized trial, concur...

Enrolling
Breast Cancer
Radiation: Focal Radiation therapy
Biological: CDX-301

Phase 2

Weill Cornell Medicine (WCM)
Weill Cornell Medicine (WCM)

Pittsburgh, Pennsylvania, United States and 7 other locations

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