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Find clinical trials for Chronic Lymphocytic Leukemia in Charlotte, NC

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Related conditions:

B-Cell Chronic Lymphocytic Leukemia
Leukemia
Lymphoid Leukemia
Lymphoma
B-Cell Lymphoma
Mantle-Cell Lymphoma
Non-Hodgkin Lymphoma

Chronic Lymphocytic Leukemia trials near Charlotte, NC, USA:

A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (MAJIC)

A study of acalabrutinib plus venetoclax (AV) versus venetoclax plus obinutuzumab (VO) in previously untreated chronic lymphocytic ...

Active, not recruiting
Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma
Drug: Obinutuzumab
Drug: Venetoclax

Phase 3

AstraZeneca
AstraZeneca

Charlotte, North Carolina, United States and 40 other locations

Chronic lymphocytic leukemia (CLL) is the most common leukemia (cancer of blood cells). The purpose of this study...

Enrolling
Chronic Lymphocytic Leukemia (CLL)
Drug: Venetoclax
Drug: Obinutuzumab

Phase 2

AbbVie
AbbVie

Charlotte, North Carolina, United States and 47 other locations

The purpose of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL. Participants...

Enrolling
Leukemia, B-cell
Small Lymphocytic Lymphoma
Drug: Pirtobrutinib
Drug: Ibrutinib

Phase 3

Loxo Oncology
Loxo Oncology

Charlotte, North Carolina, United States and 206 other locations

The purpose of this study is to assess progression-free survival (PFS) from treatment with ibrutinib plus venetoclax (I+VEN) compared with obinutuzum...

Active, not recruiting
Leukemia, Lymphocytic, Chronic, B-Cell
Drug: Obinutuzumab
Drug: Venetoclax

Phase 3

Janssen
Janssen

Charlotte, North Carolina, United States and 85 other locations

This is a study for patients with chronic lymphocytic leukemia (CLL) or small lymphocytic leukemia (SLL)...

Enrolling
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Idelalisib
Drug: Bendamustine

Phase 3

Loxo Oncology
Loxo Oncology

Rock Hill, South Carolina, United States of America and 231 other locations

participants with hypogammaglobulinemia (HGG) associated with B-cell chronic lymphocytic leukemia (CLL) in comparison to t...

Enrolling
B-cell Chronic Lymphocytic Leukemia
Hypogammaglobulinemia
Drug: Xembify
Drug: Placebo

Phase 3

Grifols
Grifols

Rockville, South Carolina, United States and 25 other locations

The purpose of this study is to compare the efficacy and safety of fixed duration pirtobruitinib (LOXO-305) with VR (Arm A) compared to VR alone (Arm...

Enrolling
Small Lymphocytic Lymphoma
Chronic Lymphocytic Leukemia
Drug: Venetoclax
Drug: Rituximab

Phase 3

Loxo Oncology
Loxo Oncology

Charlotte, North Carolina, United States and 196 other locations

Follicular Lymphoma is a slow-growing type of non-Hodgkin lymphoma. Chronic lymphocytic leukemia (CLL) is the most common ...

Enrolling
Chronic Lymphocytic Leukemia
Follicular Lymphoma
Drug: ABBV-319

Phase 1

AbbVie
AbbVie

Charlotte, North Carolina, United States and 12 other locations

The purpose of this study is to evaluate the efficacy and safety of acalabrutinib in combination with venetoclax and acalabrutinib in combination wit...

Active, not recruiting
Chronic Lymphocytic Leukemia
Drug: Venetoclax
Drug: Obinutuzumab

Phase 3

Acerta Pharma
Acerta Pharma

Charlotte, North Carolina, United States and 170 other locations

B-cell malignancies are a group of cancers of B lymphocytes, a type of white blood cell responsible for fighting infections. The purpose of ...

Enrolling
Chronic Lymphocytic Leukemia
Non-Hodgkin's Lymphoma
Drug: ABBV-525

Phase 1

AbbVie
AbbVie

Charlotte, North Carolina, United States and 21 other locations

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