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Find clinical trials for Colon Cancer in Aurora, CO

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Lung Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Pancreatic Cancer

Colon Cancer trials near Aurora, CO, USA:

Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (KISIMA-01)

with histologically or cytologically confirmed stage IV colorectal cancer coming form three different patient populations:* Cohort 1a: 6 pat...

Active, not recruiting
Stage IV Rectal Cancer
Metastatic Colorectal Cancer
Drug: ATP128
Drug: BI 754091

Phase 1

Amal Therapeutics

Aurora, Colorado, United States and 11 other locations

and irinotecan) in participants with metastatic colorectal cancer (mCRC). The main goals of this study are to:* Evaluate the efficacy of the...

Enrolling
Colorectal Cancer (CRC)
Colon Cancer
Drug: FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)
Drug: fruquintinib

Phase 2

SCRI Development Innovations

Denver, Colorado, United States and 5 other locations

aggressive and challenging to treat. The study will test whether GSK4418959 alone or in combination with a PD-1 inhibitor agent can decrease tumor...

Enrolling
Endometrial Cancer
Solid Tumor
Drug: GSK4418959
Biological: PD-1 inhibitor

Phase 1, Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Denver, Colorado, United States and 12 other locations

of ST316 administered IV in subjects with selected advanced solid tumors likely to harbor abnormalities of the WNT/β-catenin signaling pathw...

Enrolling
Colon Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: FOLFIRI regimen & bevacizumab

Phase 1

Sapience Therapeutics

Denver, Colorado, United States and 10 other locations

Data from a prior phase II study of single agent cabozantinib in metastatic, refractory colorectal cancer (NCT03542877) combined with the co...

Active, not recruiting
Rectum Cancer
Colon Cancer
Drug: Nivolumab
Drug: Cabozantinib

Phase 2

University of Colorado Denver (CU Denver)
University of Colorado Denver (CU Denver)

Aurora, Colorado, United States and 4 other locations

RSC-101 is a Phase 1a/1b clinical trial of RSC-1255 in adult study participants with advanced solid tumor malignancies who are intolerant of...

Enrolling
Colon Cancer
Lung Cancer
Drug: RSC-1255 Dose Expansion
Drug: RSC-1255 Dose Escalation

Phase 1

Rascal Therapeutics

Denver, Colorado, United States and 2 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Denver, Colorado, United States and 84 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Active, not recruiting
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Aurora, Colorado, United States and 25 other locations

This study is to evaluate the safety, tolerability, and PK profiles of RMC-6291 and RMC-6236 in adults with KRAS G12C-mutated solid tumors....

Enrolling
Non-Small Cell Lung Cancer (NSCLC)
Colorectal Cancer
Drug: Assigned interventions

Phase 1

Revolution Medicines
Revolution Medicines

Aurora, Colorado, United States and 53 other locations

to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...

Enrolling
Advanced Solid Tumor
Non-small Cell Lung Cancer
Drug: Pembrolizumab
Drug: Irinotecan

Phase 1

Lilly
Lilly

Denver, Colorado, United States and 56 other locations

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