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Find clinical trials for Colon Cancer in Aurora, CO

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Related conditions:

Colonic Cancer
Colorectal Cancer
Rectal Cancer
Non-Small-Cell Lung Carcinoma
Pancreatic Cancer
Cancer
Neoplasm Metastasis

Colon Cancer trials near Aurora, CO, USA:

Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (KISIMA-01)

with histologically or cytologically confirmed stage IV colorectal cancer coming form three different patient populations:* Cohort 1a: 6 pat...

Active, not recruiting
Stage IV Rectal Cancer
Metastatic Colorectal Cancer
Drug: ATP128
Drug: BI 754091

Phase 1

Amal Therapeutics

Aurora, Colorado, United States and 11 other locations

and irinotecan) in participants with metastatic colorectal cancer (mCRC). The main goals of this study are to:* Evaluate the efficacy of the...

Enrolling
Colorectal Cancer (CRC)
Colon Cancer
Drug: fruquintinib
Drug: FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)

Phase 2

SCRI Development Innovations

Denver, Colorado, United States and 13 other locations

Solid tumours are abnormal lumps of tissue that can occur in different parts of the body. The tumours involved in this study have specific genetic ch...

Active, not recruiting
Endometrial Cancer
Colon Cancer
Drug: GSK4418959
Biological: PD-1 inhibitor

Phase 1, Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Denver, Colorado, United States and 21 other locations

This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept effi...

Active, not recruiting
Colon Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: FOLFIRI regimen & bevacizumab

Phase 1

Sapience Therapeutics

Denver, Colorado, United States and 10 other locations

RSC-101 is a Phase 1a/1b clinical trial of RSC-1255 in adult study participants with advanced solid tumor malignancies who are intolerant of existing...

Enrolling
Colon Cancer
Lung Cancer
Drug: RSC-1255 Dose Expansion
Drug: RSC-1255 Dose Escalation

Phase 1

Rascal Therapeutics

Denver, Colorado, United States and 2 other locations

Data from a prior phase II study of single agent cabozantinib in metastatic, refractory colorectal cancer (NCT03542877) combined with the co...

Active, not recruiting
Rectum Cancer
Colon Cancer
Drug: Nivolumab
Drug: Cabozantinib

Phase 2

University of Colorado Denver (CU Denver)
University of Colorado Denver (CU Denver)

Aurora, Colorado, United States and 4 other locations

to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...

Active, not recruiting
Colon Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Denver, Colorado, United States and 85 other locations

the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Aurora, Colorado, United States and 1076 other locations

test whether GSK5460025 alone or in combination (potential combinations may be included in future amendments to the protocol) with other anti-cancer...

Enrolling
Neoplasms
Neoplasms, Colorectal
Drug: GSK5460025

Phase 1, Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Aurora, Colorado, United States and 21 other locations

This study is designed to characterize the safety, tolerability, and anti-tumor activity of MDX2001 in patients with advanced solid tumors.

Enrolling
Breast Cancer
Esophageal Cancer
Drug: MDX2001

Phase 1, Phase 2

ModeX Therapeutics

Denver, Colorado, United States and 5 other locations

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