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Find clinical trials for Colon Cancer in Aurora, CO

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Related conditions:

Colonic Cancer
Colorectal Cancer
Rectal Cancer
Pancreatic Cancer
Neoplasm Metastasis
Cancer
Non-Small-Cell Lung Carcinoma

Colon Cancer trials near Aurora, CO, USA:

Phase 1b Study to Evaluate ATP128, VSV-GP128 and BI 754091, in Patients With Stage IV Colorectal Cancer (KISIMA-01)

with histologically or cytologically confirmed stage IV colorectal cancer coming form three different patient populations:* Cohort 1a: 6 pat...

Active, not recruiting
Stage IV Rectal Cancer
Metastatic Colorectal Cancer
Drug: ATP128
Drug: BI 754091

Phase 1

Amal Therapeutics

Aurora, Colorado, United States and 11 other locations

and irinotecan) in participants with metastatic colorectal cancer (mCRC). The main goals of this study are to:* Evaluate the efficacy of the...

Enrolling
Colorectal Cancer (CRC)
Colon Cancer
Drug: fruquintinib
Drug: FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)

Phase 2

SCRI Development Innovations

Denver, Colorado, United States and 13 other locations

aggressive and challenging to treat. The study will test whether GSK4418959 alone or in combination with a PD-1 inhibitor agent can decrease tumor...

Active, not recruiting
Endometrial Cancer
Solid Tumor
Drug: GSK4418959
Biological: PD-1 inhibitor

Phase 1, Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Denver, Colorado, United States and 21 other locations

of ST316 administered IV in subjects with selected advanced solid tumors likely to harbor abnormalities of the WNT/β-catenin signaling pathw...

Enrolling
Colon Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: FOLFIRI regimen & bevacizumab

Phase 1

Sapience Therapeutics

Denver, Colorado, United States and 10 other locations

RSC-101 is a Phase 1a/1b clinical trial of RSC-1255 in adult study participants with advanced solid tumor malignancies who are intolerant of...

Enrolling
Colon Cancer
Lung Cancer
Drug: RSC-1255 Dose Expansion
Drug: RSC-1255 Dose Escalation

Phase 1

Rascal Therapeutics

Denver, Colorado, United States and 2 other locations

Data from a prior phase II study of single agent cabozantinib in metastatic, refractory colorectal cancer (NCT03542877) combined with the co...

Active, not recruiting
Rectum Cancer
Colon Cancer
Drug: Nivolumab
Drug: Cabozantinib

Phase 2

University of Colorado Denver (CU Denver)
University of Colorado Denver (CU Denver)

Aurora, Colorado, United States and 4 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Denver, Colorado, United States and 85 other locations

test whether GSK5460025 alone or in combination (potential combinations may be included in future amendments to the protocol) with other anti-cancer...

Enrolling
Neoplasms
Neoplasms, Colorectal
Drug: GSK5460025

Phase 1, Phase 2

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Aurora, Colorado, United States and 18 other locations

tolerability, and PK profiles of Elironrasib and Daraxonrasib as monotherapies and combination therapy in patients with KRAS G12C-mutated solid tumors...

Enrolling
Non-Small Cell Lung Cancer (NSCLC)
Colorectal Cancer
Drug: Elironrasib
Drug: Daraxonrasib

Phase 1, Phase 2

Revolution Medicines
Revolution Medicines

Aurora, Colorado, United States and 52 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Active, not recruiting
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: Selpercatinib

Phase 1, Phase 2

Lilly
Lilly

Aurora, Colorado, United States and 25 other locations

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