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and pembrolizumab, before surgery can treat a common type of colon cancer called microsatellite stable (MSS) colon cancer...
Phase 2
Baltimore, Maryland, United States and 29 other locations
(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...
Phase 3
Bethesda, Maryland, United States and 262 other locations
and irinotecan) in participants with metastatic colorectal cancer (mCRC). The main goals of this study are to:* Evaluate the efficacy of the...
Phase 2
Columbia, Maryland, United States and 13 other locations
activity of CBI-1214 in participants with advanced or metastatic Microsatellite Stable (MSS)/Microsatellite Instability Low (MSI-L) Colorectal Cancer...
Phase 1
Fairfax, Virginia, United States of America and 9 other locations
or metastatic mismatch repair-proficient (MMR-p) colorectal cancer (mCRC) or unresectable or metastatic MMR-p pancreatic ductal adenocarcino...
Phase 1
Baltimore, Maryland, United States
This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitr...
Phase 1
Baltimore, Maryland, United States and 32 other locations
to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...
Phase 1, Phase 2
Baltimore, Maryland, United States and 85 other locations
This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant sol...
Phase 1
Baltimore, Maryland, United States and 16 other locations
This first-in-human study will evaluate safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of PHN-012,...
Phase 1
Washington D.C., District of Columbia, United States and 25 other locations
and/or radiation, as well as patients with metastatic colorectal cancer who have exposure to 2 or more lines of chemotherapy, to evaluate sa...
Phase 1
Baltimore, Maryland, United States
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