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Find clinical trials for Colon Cancer in Birmingham, AL

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Related conditions:

Colonic Cancer
Colorectal Cancer
Rectal Cancer
Non-Small-Cell Lung Carcinoma
Pancreatic Cancer
Cancer
Neoplasm Metastasis

Colon Cancer trials near Birmingham, AL, USA:

A Phase 1-2 of ST316 With Selected Advanced Unresectable and Metastatic Solid Tumors

This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept effi...

Active, not recruiting
Colon Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: FOLFIRI regimen & bevacizumab

Phase 1

Sapience Therapeutics

Birmingham, Alabama, United States and 10 other locations

the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Birmingham, Alabama, United States and 1076 other locations

The main purpose of the study is to assess whether the study drug, LY4066434, is safe and tolerable when administered to participants with locally ad...

Active, not recruiting
Non-small Cell Lung Cancer
Colorectal Cancer
Drug: Pembrolizumab
Drug: Irinotecan

Phase 1

Lilly
Lilly

Birmingham, Alabama, United States and 46 other locations

PRE-ISPY Phase I/II (I-SPY-P1) is an open-label, multisite platform study with multiple ongoing drug regimen arms added by protocol amendment which i...

Enrolling
Colon Cancer
Colo-rectal Cancer
Drug: Fam-Trastuzumab Deruxtecan-Nxki
Drug: TTX-MC138

Phase 1, Phase 2

QuantumLeap Healthcare Collaborative

Birmingham, Alabama, United States and 9 other locations

This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with adva...

Active, not recruiting
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Birmingham, Alabama, United States and 231 other locations

Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab ver...

Active, not recruiting
Metastatic Colorectal Cancer
Advanced Colorectal Cancer
Drug: MRTX849
Biological: Cetuximab

Phase 3

Mirati Therapeutics
Mirati Therapeutics

Birmingham, Alabama, United States and 427 other locations

a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon...

Active, not recruiting
Colorectal Neoplasms
Drug: Eflornithine placebo & sulindac placebo
Drug: Eflornithine plus sulindac

Phase 3

SWOG Cancer Research Network
SWOG Cancer Research Network

Birmingham, Alabama, United States and 990 other locations

2 mutations. These include tumors in the colon or rectum, the uterus and the cervix (lower part of the uterus), the breast, the bladder, and...

Enrolling
Advanced Solid Tumors
HER2 Mutation
Drug: BAY2927088

Phase 2

Bayer
Bayer

Birmingham, Alabama, United States and 55 other locations

without biological agent and monalizumab (IPH2201) with biological agent administered to participants with recurrent or metastatic colorectal cancer...

Active, not recruiting
Advanced Solid Tumors
Drug: Durvalumab
Drug: Bevacizumab

Phase 1, Phase 2

MedImmune
MedImmune

Birmingham, Alabama, United States and 48 other locations

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