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Find clinical trials for Colon Cancer in Birmingham, AL

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Adenocarcinoma
Carcinoma

Colon Cancer trials near Birmingham, AL, USA:

A Phase 1-2 of ST316 With Selected Advanced Unresectable and Metastatic Solid Tumors

of ST316 administered IV in subjects with selected advanced solid tumors likely to harbor abnormalities of the WNT/β-catenin signaling pathw...

Enrolling
Colon Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: FOLFIRI regimen & bevacizumab

Phase 1

Sapience Therapeutics

Birmingham, Alabama, United States and 7 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Birmingham, Alabama, United States and 927 other locations

to participants with locally advanced or metastatic solid tumors with certain KRAS mutations. LY4066434 will be given alone or in combinatio...

Enrolling
Advanced Solid Tumor
Non-small Cell Lung Cancer
Drug: Pembrolizumab
Drug: Irinotecan

Phase 1

Lilly
Lilly

Birmingham, Alabama, United States and 44 other locations

evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...

Enrolling
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Birmingham, Alabama, United States and 219 other locations

Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab ver...

Active, not recruiting
Metastatic Colorectal Cancer
Advanced Colorectal Cancer
Drug: MRTX849
Biological: Cetuximab

Phase 3

Mirati Therapeutics
Mirati Therapeutics

Birmingham, Alabama, United States and 427 other locations

a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon...

Active, not recruiting
Colorectal Neoplasms
Drug: Eflornithine placebo & sulindac placebo
Drug: Eflornithine plus sulindac

Phase 3

SWOG Cancer Research Network
SWOG Cancer Research Network

Birmingham, Alabama, United States and 989 other locations

without biological agent and monalizumab (IPH2201) with biological agent administered to participants with recurrent or metastatic colorectal cancer...

Active, not recruiting
Advanced Solid Tumors
Drug: Durvalumab
Drug: Bevacizumab

Phase 1, Phase 2

MedImmune
MedImmune

Birmingham, Alabama, United States and 48 other locations

include tumors in the colon or rectum, the uterus and the cervix (lower part of the uterus), the bladder, and the biliary tract (i...

Enrolling
Advanced Solid Tumors
HER2 Mutation
Drug: BAY2927088

Phase 2

Bayer
Bayer

Birmingham, Alabama, United States and 50 other locations

who have newly diagnosed metastatic adenocarcinoma of the colon/rectum. The study will also evaluate if the administration of BXQ-350 with m...

Active, not recruiting
Neuropathy
Metastatic Colorectal Carcinoma
Other: Placebo
Drug: BXQ-350

Phase 1, Phase 2

Bexion Pharmaceuticals

Birmingham, Alabama, United States and 11 other locations

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