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Find clinical trials for Colon Cancer in Chicago, IL

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Lung Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Adenocarcinoma

Colon Cancer trials near Chicago, IL, USA:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Chicago, Illinois, United States and 250 other locations

dehydrogenase 1 (IDH1) arginine 132 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, an...

Active, not recruiting
Any Solid Tumor
Glioma
Drug: LY3410738
Drug: Gemcitabine

Phase 1

Lilly
Lilly

Chicago, Illinois, United States and 32 other locations

and pembrolizumab) given together for the treatment of colorectal cancer that:* is metastatic (spread to other parts of the body);* has the ...

Active, not recruiting
Metastatic Colorectal Cancer
Biological: Pembrolizumab
Biological: Cetuximab

Phase 2

Pfizer
Pfizer

Chicago, Illinois, United States and 111 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Chicago, Illinois, United States and 83 other locations

dose escalation and expansion study to determine the safety and effectiveness of ²¹²Pb-DOTAM-GRPR1 in subjects with various GRPR-expressing Tumors...

Enrolling
Breast Cancer
Colon Cancer
Drug: ²¹²Pb-DOTAM-GRPR1

Phase 1

Orano Med

Chicago, Illinois, United States and 3 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Chicago, Illinois, United States and 899 other locations

tolerability, drug levels, molecular effects, and clinical activity of MRTX849 in combination with TNO155 in patients with advanced solid tumors...

Active, not recruiting
Metastatic Cancer
Advanced Cancer
Drug: TNO155
Drug: MRTX849

Phase 1

Mirati Therapeutics
Mirati Therapeutics

Chicago, Illinois, United States and 11 other locations

This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody ta...

Enrolling
SDH-deficient Solid Tumors
Solid Tumors
Drug: 5-fluorouracil
Drug: Carboplatin

Phase 1

Inhibrx

Chicago, Illinois, United States and 18 other locations

plus BSC in participants with refractory metastatic colorectal cancer (mCRC). 691 participants were randomized to one of the following treat...

Active, not recruiting
Metastatic Colorectal Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: Placebo

Phase 3

HUTCHMED
HUTCHMED

Chicago, Illinois, United States and 152 other locations

evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...

Enrolling
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Chicago, Illinois, United States and 219 other locations

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