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Find clinical trials for Colon Cancer in Chicago, IL

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Related conditions:

Colonic Cancer
Colorectal Cancer
Rectal Cancer
Non-Small-Cell Lung Carcinoma
Pancreatic Cancer
Cancer
Neoplasm Metastasis

Colon Cancer trials near Chicago, IL, USA:

Neoadjuvant Pembrolizumab and Porustobart in Resectable pMMR/MSS Colon Cancer

and pembrolizumab, before surgery can treat a common type of colon cancer called microsatellite stable (MSS) colon cancer...

Begins enrollment this month
Proficient Mismatch Repair (pMMR) Colon Cancer
Microsatellite Stable (MSS) Colon Cancer
Drug: Porustobart
Drug: Pembrolizumab

Phase 2

Solstice Oncology, Inc.

Chicago, Illinois, United States and 29 other locations

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Chicago, Illinois, United States and 262 other locations

and irinotecan) in participants with metastatic colorectal cancer (mCRC). The main goals of this study are to:* Evaluate the efficacy of the...

Enrolling
Colorectal Cancer (CRC)
Colon Cancer
Drug: fruquintinib
Drug: FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)

Phase 2

SCRI Development Innovations

Arlington Heights, Illinois, United States and 13 other locations

This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitr...

Active, not recruiting
Glioma
Chondrosarcoma
Drug: LY3410738
Drug: Gemcitabine

Phase 1

Lilly
Lilly

Chicago, Illinois, United States and 32 other locations

to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...

Active, not recruiting
Colon Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Chicago, Illinois, United States and 85 other locations

The purpose of this study is to assess the safety and tolerability of XmAb®819 administered intravenous (IV) or subcutaneous (SC) in subjects with re...

Enrolling
Clear Cell Renal Cell Carcinoma
Biological: XmAb819

Phase 1

Xencor
Xencor

Chicago, Illinois, United States and 26 other locations

the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Chicago, Illinois, United States and 1076 other locations

A Phase 1 Open-Label, First-in-human, Dose Escalation and Expansion Study to Determine the Safety, Tolerability, Dosimetry, Pharmacokinetics, and Pre...

Enrolling
Breast Cancer
Nonsmall Cell Lung Cancer
Drug: ²¹²Pb-DOTAM-GRPR1

Phase 1

Orano Med Theranostics, SAS

Chicago, Illinois, United States and 7 other locations

The main purpose of the study is to assess whether the study drug, LY4066434, is safe and tolerable when administered to participants with locally ad...

Active, not recruiting
Non-small Cell Lung Cancer
Colorectal Cancer
Drug: Pembrolizumab
Drug: Irinotecan

Phase 1

Lilly
Lilly

Chicago, Illinois, United States and 46 other locations

PRE-ISPY Phase I/II (I-SPY-P1) is an open-label, multisite platform study with multiple ongoing drug regimen arms added by protocol amendment which i...

Enrolling
Colon Cancer
Colo-rectal Cancer
Drug: Fam-Trastuzumab Deruxtecan-Nxki
Drug: TTX-MC138

Phase 1, Phase 2

QuantumLeap Healthcare Collaborative

Chicago, Illinois, United States and 9 other locations

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