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Find clinical trials for Colon Cancer in Cincinnati, OH

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Non-Small-Cell Lung Carcinoma
Neoplasm Metastasis
Lung Cancer
Pancreatic Cancer

Colon Cancer trials near Cincinnati, OH, USA:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Cincinnati, Ohio, United States and 249 other locations

is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors...

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236
Drug: RMC-9805

Phase 1

Revolution Medicines
Revolution Medicines

Cincinnati, Ohio, United States and 16 other locations

Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors....

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236

Phase 1

Revolution Medicines
Revolution Medicines

Cincinnati, Ohio, United States and 15 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Active, not recruiting
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Cincinnati, Ohio, United States and 25 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Cincinnati, Ohio, United States and 1004 other locations

in very high numbers).This includes (but limited to) the following cancer types:Non-Small Cell Lung Cancer (NSCLC): It's a type of ...

Enrolling
Colorectal Neoplasms
Carcinoma, Pancreatic Ductal
Combination Product: pemetrexed
Combination Product: Cetuximab

Phase 1

Pfizer
Pfizer

Cincinnati, Ohio, United States and 25 other locations

evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...

Active, not recruiting
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Cincinnati, Ohio, United States and 231 other locations

This is a Phase 1/2, open-label, multicenter, study evaluating the safety, tolerability, PK, PD, and anti-tumor activity of MRTX0902 alone a...

Active, not recruiting
Solid Tumor
Advanced Solid Tumor
Drug: MRTX0902
Drug: MRTX849

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Cincinnati, Ohio, United States and 17 other locations

Researchers are looking for other ways to treat locally advanced or metastatic colorectal cancer (mCRC) that is unresectable and has a gene ...

Enrolling
Colon Adenocarcinoma
Rectal Adenocarcinoma
Drug: Oxaliplatin
Drug: MK-1084

Phase 3

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

Centerville, Ohio, United States and 51 other locations

of RO7198457 versus watchful waiting in patients with circulating tumor DNA (ctDNA) positive, surgically resected Stage II/III rectal cancer...

Enrolling
Colorectal Cancer Stage III
Colorectal Cancer Stage II
Drug: RO7198457 intravenous (IV)
Other: Observational group (no intervention)

Phase 2

BioNTech
BioNTech

Cincinnati, Ohio, United States and 121 other locations

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