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Find clinical trials for Colon Cancer in Dallas, TX

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Neoplasm Metastasis
Lung Cancer
Non-Small-Cell Lung Carcinoma
Adenocarcinoma

Colon Cancer trials near Dallas, TX, USA:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Dallas, Texas, United States and 250 other locations

is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors...

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236
Drug: RMC-9805

Phase 1

Revolution Medicines
Revolution Medicines

Dallas, Texas, United States and 16 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Enrolling
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Dallas, Texas, United States and 83 other locations

Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors....

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Colorectal Cancer (CRC)
Drug: RMC-6236

Phase 1

Revolution Medicines
Revolution Medicines

Dallas, Texas, United States and 14 other locations

the efficacy of CTX-009 in patients with metastatic colorectal cancer.A Simon Two-Stage adaptive design will enroll approximately 37 patient...

Active, not recruiting
Metastatic Colorectal Cancer
Colon Cancer
Drug: CTX-009

Phase 2

Compass Therapeutics

Dallas, Texas, United States and 6 other locations

This study is to evaluate the safety, tolerability, and PK profiles of RMC-6291 and RMC-6236 in adults with KRAS G12C-mutated solid tumors....

Enrolling
Non-Small Cell Lung Cancer (NSCLC)
Colorectal Cancer
Drug: Assigned interventions

Phase 1

Revolution Medicines
Revolution Medicines

Dallas, Texas, United States and 27 other locations

oral LOXO-292 in pediatric participants with an activating rearranged during transfection (RET) alteration and an advanced solid or primary CNS tumor...

Enrolling
Papillary Thyroid Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Dallas, Texas, United States and 25 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Dallas, Texas, United States and 878 other locations

Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary antitumor activity of CO...

Enrolling
Advanced Cancer
Colon Cancer
Drug: Cohort expansion: COM902 (RDFE) monotherapy.
Combination Product: Cohort expansion: Triplet combination of COM902 + COM701 + Pembrolizumab.

Phase 1

Compugen

Dallas, Texas, United States and 8 other locations

known as MVC-101) in adults with unremovable advanced or metastatic cancer. Another aim is to characterize and evaluate the activity of TAK-...

Enrolling
Non-small Cell Lung Cancer (NSCLC)
Squamous Cell Cancer of Head and Neck (SCCHN)
Drug: TAK-186

Phase 1, Phase 2

Takeda
Takeda

Dallas, Texas, United States and 19 other locations

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