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Find clinical trials for Colon Cancer in Jacksonville, FL

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Neoplasm Metastasis
Adenocarcinoma
Lung Cancer
Non-Small-Cell Lung Carcinoma

Colon Cancer trials near Jacksonville, FL, USA:

A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)

to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...

Enrolling
Colon Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Jacksonville, Florida, United States and 83 other locations

Recently updated

This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitr...

Active, not recruiting
Glioma
Chondrosarcoma
Drug: LY3410738
Drug: Gemcitabine

Phase 1

Lilly
Lilly

Jacksonville, Florida, United States and 32 other locations

plus BSC in participants with refractory metastatic colorectal cancer (mCRC). 691 participants were randomized to one of the following treat...

Active, not recruiting
Metastatic Colorectal Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: Placebo

Phase 3

HUTCHMED
HUTCHMED

Jacksonville, Florida, United States and 152 other locations

This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with adva...

Enrolling
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Jacksonville, Florida, United States and 112 other locations

The goal of this study is to test A2B694, an autologous logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorectal cancer...

Enrolling
Colon Cancer
Lung Cancer
Diagnostic Test: xT CDx with HLA-LOH Assay
Biological: A2B694

Phase 1, Phase 2

A2 Biotherapeutics

Jacksonville, Florida, United States and 8 other locations

This is a Phase 1/2 study to assess the safety and efficacy of ELI-002 7P immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide \[Amph...

Enrolling
Colorectal Cancer
KRAS G12V
Drug: ELI-002 7P

Phase 1, Phase 2

Elicio Therapeutics
Elicio Therapeutics

Jacksonville, Florida, United States and 25 other locations

The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...

Active, not recruiting
Esophageal Cancer
Urologic Cancer
Drug: Niraparib

Phase 2

Tempus AI
Tempus AI

Jacksonville, Florida, United States and 79 other locations

Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab ver...

Active, not recruiting
Metastatic Colorectal Cancer
Advanced Colorectal Cancer
Drug: MRTX849
Biological: Cetuximab

Phase 3

Mirati Therapeutics
Mirati Therapeutics

Jacksonville, Florida, United States and 282 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Active, not recruiting
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Jacksonville, Florida, United States and 409 other locations

tumor DNA (ctDNA) positive, surgically resected Stage II/III rectal cancer, or Stage II (high risk)/Stage III colon cancer....

Enrolling
Colorectal Cancer Stage III
Colorectal Cancer Stage II
Drug: RO7198457 intravenous (IV)
Other: Observational group (no intervention)

Phase 2

BioNTech
BioNTech

Jacksonville, Florida, United States and 112 other locations

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