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Find clinical trials for Colon Cancer in Madrid, MD

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Neoplasm Metastasis
Adenocarcinoma
Lung Cancer
Pancreatic Cancer

Colon Cancer trials near Madrid, MD, ESP:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: FOLFOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Madrid, Spain and 212 other locations

The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in mea ...

Active, not recruiting
Microsatellite Unstable Colorectal Cancer
Microsatellite Stable Colorectal Cancer
Drug: Ipilimumab
Drug: Daratumumab

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Madrid, Spain and 32 other locations

The purpose of this study is to measure tumor response to treatment with ompenaclid (RGX-202) in patients with previously treated RAS mutant advanced...

Enrolling
Metastatic Colon Cancer
Colorectal Cancer
Drug: FOLFIRI regimen
Drug: Ompenaclid (RGX-202)

Phase 2

Inspirna

Madrid, Spain and 27 other locations

and pembrolizumab) given together for the treatment of colorectal cancer that:is metastatic (spread to other parts of the body);has the cond...

Enrolling
Metastatic Colorectal Cancer
Biological: Pembrolizumab
Biological: Cetuximab

Phase 2

Pfizer
Pfizer

Madrid, Madrid, Comunidad DE, Spain and 108 other locations

This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitr...

Active, not recruiting
Glioma
Chondrosarcoma
Drug: Cisplatin
Drug: LY3410738

Phase 1

Lilly
Lilly

Madrid, Spain and 32 other locations

to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...

Enrolling
Colon Cancer
Medullary Thyroid Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Madrid, Spain and 83 other locations

A phase Ib, open-label platform study of select drug combinations chosen in order to characterize safety and tolerability of each treatment arm teste...

Active, not recruiting
BRAF V600 Colorectal Cancer
Drug: TNO155
Biological: Spartalizumab

Phase 1

Novartis
Novartis

Madrid, Spain and 17 other locations

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of escalating doses of RMC-6291 (KRAS G12C(ON) inhibitor...

Enrolling
Colorectal Cancer (CRC)
Non-Small Cell Lung Cancer (NSCLC)
Drug: RMC-6291

Phase 1

Revolution Medicines
Revolution Medicines

Madrid, Spain and 63 other locations

plus BSC in participants with refractory metastatic colorectal cancer (mCRC). 691 participants were randomized to one of the following treat...

Active, not recruiting
Metastatic Colorectal Cancer
Metastatic Colon Cancer
Drug: Fruquintinib
Drug: Placebo

Phase 3

HUTCHMED
HUTCHMED

Madrid, ESP, Spain and 152 other locations

tislelizumab or irinotecan that can be given to patients who have cancers with specific molecular alterations called MSIhi (Microsatellite I...

Enrolling
MSIhi or dMMR Advanced Unresectable or Metastatic Solid Tumors, Including Colorectal Cancers
Drug: irinotecan
Biological: tislelizumab

Phase 1

Novartis
Novartis

Madrid, Spain and 18 other locations

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