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." . The aim is to see if this new approach can show early signs of effectiveness in treating participants with a specific type of colon cancer...
Phase 2
Madrid, Spain and 14 other locations
(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...
Phase 3
Madrid, Spain and 250 other locations
The purpose of this study is to measure tumor response to treatment with ompenaclid (RGX-202-01) in patients with previously treated RAS mut...
Phase 2
Madrid, Spain and 27 other locations
and pembrolizumab) given together for the treatment of colorectal cancer that:* is metastatic (spread to other parts of the body);* has the ...
Phase 2
Madrid, Madrid, Comunidad DE, Spain and 111 other locations
dehydrogenase 1 (IDH1) arginine 132 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, an...
Phase 1
Madrid, Spain and 32 other locations
This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...
Phase 1, Phase 2
Madrid, Spain and 83 other locations
This study is to evaluate the safety, tolerability, and PK profiles of RMC-6291 and RMC-6236 in adults with KRAS G12C-mutated solid tumors....
Phase 1
Madrid, Spain and 27 other locations
The goal of this low-risk interventional study is to analyze participants' assessment of colorectal cancer screening program through screeni...
Madrid, Spain and 1 other location
inhibitor) monotherapy in adult subjects with advanced solid tumors and to identify the maximum tolerated dose (MTD), and the recommended Ph...
Phase 1
Madrid, Spain and 63 other locations
pembrolizumab or irinotecan that can be given to patients who have cancers with specific molecular alterations called MSIhi (Microsatellite ...
Phase 1
Madrid, Spain and 22 other locations
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