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(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...
Phase 3
New Haven, Connecticut, United States and 262 other locations
This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept effi...
Phase 1
Valhalla, New York, United States and 10 other locations
This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitr...
Phase 1
Commack, New York, United States and 32 other locations
to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...
Phase 1, Phase 2
New Haven, Connecticut, United States and 85 other locations
This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant sol...
Phase 1
New Haven, Connecticut, United States and 16 other locations
The purpose of this study is to assess the safety and tolerability of XmAb®819 administered intravenous (IV) or subcutaneous (SC) in subjects with re...
Phase 1
New Haven, Connecticut, United States and 26 other locations
the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...
Phase 2, Phase 3
New Haven, Connecticut, United States and 1076 other locations
This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced Cancer...
Phase 1, Phase 2
New Haven, Connecticut, United States and 13 other locations
The main purpose of the study is to assess whether the study drug, LY4066434, is safe and tolerable when administered to participants with locally ad...
Phase 1
New Haven, Connecticut, United States and 46 other locations
for participants with metastatic and/or unresectable colorectal cancer that expresses low levels of HER2 and that has gotten worse after rec...
Phase 2
Commack, New York, United States and 6 other locations
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