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Find clinical trials for Colon Cancer in Pittsburgh, PA

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Lung Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Adenocarcinoma

Colon Cancer trials near Pittsburgh, PA, USA:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Pittsburgh, Pennsylvania, United States and 250 other locations

To confirm the safety and performance of the da Vinci SP Surgical System, Instruments and Accessories in a complex colorectal procedure such as low a...

Active, not recruiting
Benign or Malignant Rectal or Colon Tumors
Colorectal Cancer
Device: Robotic Assisted Surgery
Intuitive Surgical
Intuitive Surgical

Pittsburgh, Pennsylvania, United States and 8 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Pittsburgh, Pennsylvania, United States and 899 other locations

in combination with pembrolizumab in patients with select advanced cancers, and to identify the maximum tolerated dose and/or recommended do...

Enrolling
Anal Cancer
Triple Negative Breast Neoplasms
Drug: pembrolizumab
Drug: KFA115

Phase 1

Novartis
Novartis

Pittsburgh, Pennsylvania, United States and 12 other locations

This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemipl...

Active, not recruiting
Breast Cancer
Colon Cancer
Biological: E-602
Biological: Cemiplimab

Phase 1, Phase 2

Palleon Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 12 other locations

of SNS-101, a novel anti VISTA IgG1 monoclonal antibody as monotherapy or in combination with cemiplimab in patients with advanced solid tumors...

Enrolling
Breast Cancer
Uterine Cancer
Drug: Cemiplimab
Drug: SNS-101 (anti-VISTA)

Phase 1, Phase 2

Sensei Biotherapeutics

Pittsburgh, Pennsylvania, United States and 10 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Active, not recruiting
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Pittsburgh, Pennsylvania, United States and 409 other locations

Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab ver...

Active, not recruiting
Metastatic Colorectal Cancer
Advanced Colorectal Cancer
Drug: MRTX849
Biological: Cetuximab

Phase 3

Mirati Therapeutics
Mirati Therapeutics

Pittsburgh, Pennsylvania, United States and 393 other locations

a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon...

Active, not recruiting
Colorectal Neoplasms
Drug: Eflornithine placebo & sulindac placebo
Drug: Eflornithine plus sulindac

Phase 3

SWOG Cancer Research Network
SWOG Cancer Research Network

Bryn Mawr, Pennsylvania, United States and 989 other locations

versus a fluoropyrimidine/bevacizumab alone as assessed by molecular response which is based on changes in circulating tumor (ct)DNA. The...

Active, not recruiting
Colorectal Neoplasms
Drug: Ipilimumab
Drug: Atezolizumab

Phase 2, Phase 3

Gritstone Bio

Pittsburgh, Pennsylvania, United States and 42 other locations

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