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Find clinical trials for Colon Cancer in Pittsburgh, PA

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Neoplasm Metastasis
Adenocarcinoma
Lung Cancer
Non-Small-Cell Lung Carcinoma

Colon Cancer trials near Pittsburgh, PA, USA:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: FOLFOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Pittsburgh, Pennsylvania, United States and 212 other locations

The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in mea ...

Active, not recruiting
Microsatellite Unstable Colorectal Cancer
Microsatellite Stable Colorectal Cancer
Drug: Ipilimumab
Drug: Daratumumab

Phase 2

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Pittsburgh, Pennsylvania, United States and 32 other locations

the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology

Pittsburgh, Pennsylvania, United States and 831 other locations

in combination with pembrolizumab in patients with select advanced cancers, and to identify the maximum tolerated dose and/or recommended do...

Enrolling
Anal Cancer
Esophagogastric Cancer
Drug: KFA115
Drug: pembrolizumab

Phase 1

Novartis
Novartis

Pittsburgh, Pennsylvania, United States and 12 other locations

This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemipl...

Enrolling
Breast Cancer
Colon Cancer
Biological: Cemiplimab
Biological: E-602

Phase 1, Phase 2

Palleon Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 12 other locations

Locations recently updated

Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab ver...

Active, not recruiting
Metastatic Colorectal Cancer
Advanced Colorectal Cancer
Drug: MRTX849
Biological: Cetuximab

Phase 3

Mirati Therapeutics
Mirati Therapeutics

Pittsburgh, Pennsylvania, United States and 282 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Enrolling
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Pittsburgh, Pennsylvania, United States and 409 other locations

a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon...

Active, not recruiting
Colorectal Neoplasms
Drug: eflornithine & sulindac placebo
Drug: Eflornithine placebo & sulindac placebo

Phase 3

SWOG Cancer Research Network

Bryn Mawr, Pennsylvania, United States and 989 other locations

Recently updated

To confirm the safety and performance of the da Vinci SP Surgical System, Instruments and Accessories in a complex colorectal procedure such as low a...

Active, not recruiting
Benign or Malignant Rectal or Colon Tumors
Colorectal Cancer
Device: Robotic Assisted Surgery
Intuitive Surgical
Intuitive Surgical

Pittsburgh, Pennsylvania, United States and 8 other locations

The primary objective of the Phase 2 portion of the study is to characterize the clinical activity of maintenance therapy with GRT-C901/GRT-R902 (pat...

Active, not recruiting
Colorectal Neoplasms
Drug: Ipilimumab
Drug: Atezolizumab

Phase 2, Phase 3

Gritstone Bio

Pittsburgh, Pennsylvania, United States and 42 other locations

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