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The purpose of this study is to examine if Nivolumab by itself, or Nivolumab in combination with other anti-cancer drugs, will result in mea ...
Phase 2
Portland, Oregon, United States and 32 other locations
to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...
Phase 1, Phase 2
Portland, Oregon, United States and 83 other locations
the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...
Phase 2, Phase 3
Portland, Oregon, United States and 827 other locations
does to the body besides treating the disease.Participants will have cancer that cannot be removed (unresectable) or has spread through the ...
Phase 1
Portland, Oregon, United States and 7 other locations
This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody ta...
Phase 1
Portland, Oregon, United States and 18 other locations
This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemipl...
Phase 1, Phase 2
Portland, Oregon, United States and 12 other locations
plus BSC in participants with refractory metastatic colorectal cancer (mCRC). 691 participants were randomized to one of the following treat...
Phase 3
Vancouver, Washington, United States and 152 other locations
This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with adva...
Phase 1, Phase 2
Vancouver, Washington, United States and 97 other locations
The purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors an...
Phase 2
Salem, Oregon, United States and 79 other locations
Study 849-010 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab versus...
Phase 3
Vancouver, Washington, United States and 308 other locations
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