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Find clinical trials for Colon Cancer in Portland, OR

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Adenocarcinoma
Non-Small-Cell Lung Carcinoma
Carcinoma
Neoplasm Metastasis

Colon Cancer trials near Portland, OR, USA:

A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Portland, Oregon, United States and 84 other locations

This study will test the safety of a drug called PF-08046052/SGN-EGFRd2 in participants with advanced solid tumors. It will also study the s...

Enrolling
Colorectal Neoplasms
Squamous Cell Carcinoma of the Head and Neck
Drug: PF-08046052

Phase 1

Seagen, a wholly owned subsidiary of Pfizer

Portland, Oregon, United States and 12 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Portland, Oregon, United States and 944 other locations

This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody ta...

Enrolling
Colorectal Adenocarcinoma
Ewing Sarcoma
Drug: Pemetrexed
Drug: INBRX-109

Phase 1

Inhibrx Biosciences, Inc

Portland, Oregon, United States and 33 other locations

evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...

Enrolling
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Vancouver, Washington, United States and 219 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Active, not recruiting
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Portland, Oregon, United States and 274 other locations

of RO7198457 versus watchful waiting in patients with circulating tumor DNA (ctDNA) positive, surgically resected Stage II/III rectal cancer...

Enrolling
Colorectal Cancer Stage III
Colorectal Cancer Stage II
Drug: RO7198457 intravenous (IV)
Other: Observational group (no intervention)

Phase 2

BioNTech
BioNTech

Vancouver, Washington, United States and 117 other locations

Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab ver...

Active, not recruiting
Metastatic Colorectal Cancer
Advanced Colorectal Cancer
Drug: MRTX849
Biological: Cetuximab

Phase 3

Mirati Therapeutics
Mirati Therapeutics

Vancouver, Washington, United States and 427 other locations

a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon...

Active, not recruiting
Colorectal Neoplasms
Drug: Eflornithine placebo & sulindac placebo
Drug: Eflornithine plus sulindac

Phase 3

SWOG Cancer Research Network
SWOG Cancer Research Network

Portland, Oregon, United States and 989 other locations

versus a fluoropyrimidine/bevacizumab alone as assessed by molecular response which is based on changes in circulating tumor (ct)DNA. The...

Active, not recruiting
Colorectal Neoplasms
Drug: Ipilimumab
Drug: Atezolizumab

Phase 2, Phase 3

Gritstone Bio

Portland, Oregon, United States and 42 other locations

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