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Find clinical trials for Colon Cancer in Portland, OR

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Non-Small-Cell Lung Carcinoma
Lung Cancer
Neoplasm Metastasis
Pancreatic Cancer

Colon Cancer trials near Portland, OR, USA:

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC) (FRUITFUL)

and irinotecan) in participants with metastatic colorectal cancer (mCRC). The main goals of this study are to:* Evaluate the efficacy of the...

Enrolling
Colorectal Cancer (CRC)
Colon Cancer
Drug: FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin)
Drug: fruquintinib

Phase 2

SCRI Development Innovations

Portland, Oregon, United States and 9 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Lilly
Lilly

Portland, Oregon, United States and 85 other locations

This study will test the safety of a drug called PF-08046052/SGN-EGFRd2 in participants with advanced solid tumors. It will also study the s...

Enrolling
Colorectal Neoplasms
Squamous Cell Carcinoma of the Head and Neck
Drug: PF-08046052

Phase 1

Seagen, a wholly owned subsidiary of Pfizer

Portland, Oregon, United States and 23 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Portland, Oregon, United States and 1004 other locations

This is a first-in-human, open-label, non-randomized, three-part phase 1 trial of INBRX-109, which is a recombinant humanized tetravalent antibody ta...

Enrolling
Colorectal Adenocarcinoma
Ewing Sarcoma
Drug: Pemetrexed
Drug: INBRX-109

Phase 1

Inhibrx Biosciences, Inc

Portland, Oregon, United States and 33 other locations

evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors...

Active, not recruiting
Metastatic Cancer
Advanced Cancer
Drug: Cetuximab
Drug: Afatinib

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Vancouver, Washington, United States and 231 other locations

This is a Phase 1/2, open-label, multicenter, study evaluating the safety, tolerability, PK, PD, and anti-tumor activity of MRTX0902 alone a...

Active, not recruiting
Solid Tumor
Advanced Solid Tumor
Drug: MRTX0902
Drug: MRTX849

Phase 1, Phase 2

Mirati Therapeutics
Mirati Therapeutics

Portland, Oregon, United States and 17 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Active, not recruiting
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Portland, Oregon, United States and 270 other locations

of RO7198457 versus watchful waiting in patients with circulating tumor DNA (ctDNA) positive, surgically resected Stage II/III rectal cancer...

Enrolling
Colorectal Cancer Stage III
Colorectal Cancer Stage II
Drug: RO7198457 intravenous (IV)
Other: Observational group (no intervention)

Phase 2

BioNTech
BioNTech

Vancouver, Washington, United States and 121 other locations

Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab ver...

Active, not recruiting
Metastatic Colorectal Cancer
Advanced Colorectal Cancer
Drug: MRTX849
Biological: Cetuximab

Phase 3

Mirati Therapeutics
Mirati Therapeutics

Vancouver, Washington, United States and 427 other locations

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