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Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors....
Phase 1, Phase 2
Salt Lake City, Utah, United States and 15 other locations
The purpose of this study is to learn about the safety and effects of the study medicine when given alone or together with other anti-cancer...
Phase 1
West Valley City, Utah, United States of America and 2 other locations
This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...
Phase 1, Phase 2
Salt Lake City, Utah, United States and 85 other locations
This study will test the safety of a drug called PF-08046052/SGN-EGFRd2 in participants with advanced solid tumors. It will also study the s...
Phase 1
Salt Lake City, Utah, United States and 23 other locations
This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...
Phase 2, Phase 3
Salt Lake City, Utah, United States and 1031 other locations
of SNS-101, a novel anti VISTA IgG1 monoclonal antibody as monotherapy or in combination with cemiplimab in patients with advanced solid tumors...
Phase 1, Phase 2
West Valley City, Utah, United States of America and 9 other locations
Multicenter Study to Evaluate ALX2004, an Antibody Drug Conjugate Targeting EGFR in Participants with Advanced or Metastatic Select Solid Tumors...
Phase 1
West Valley City, Utah, United States of America and 6 other locations
multicenter, open-label FIH, Phase 1a (dose escalation), Phase 1b (dose expansion) and Phase 2 study in patients with advanced metastatic solid tumors...
Phase 1, Phase 2
West Valley City, Utah, United States and 5 other locations
Study CA239-0006 is an open-label, randomized Phase 3 clinical trial comparing the efficacy of MRTX849 administered in combination with cetuximab ver...
Phase 3
Salt Lake City, Utah, United States and 427 other locations
versus a fluoropyrimidine/bevacizumab alone as assessed by molecular response which is based on changes in circulating tumor (ct)DNA. The...
Phase 2, Phase 3
Salt Lake City, Utah, United States and 42 other locations
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