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Find clinical trials for Colon Cancer in St Louis, MO

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Related conditions:

Colorectal Cancer
Colonic Cancer
Cancer
Lung Cancer
Neoplasm Metastasis
Non-Small-Cell Lung Carcinoma
Adenocarcinoma

Colon Cancer trials near St Louis, MO, USA:

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...

Enrolling
Colonic Neoplasms
Neoplasms, Colon
Drug: CAPEOX
Biological: Dostarlimab

Phase 3

GlaxoSmithKline (GSK)
GlaxoSmithKline (GSK)

Saint Louis, Missouri, United States and 250 other locations

This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...

Active, not recruiting
Any Solid Tumor
Colon Cancer
Drug: LOXO-292

Phase 1, Phase 2

Loxo Oncology
Loxo Oncology

Saint Louis, Missouri, United States and 83 other locations

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...

Enrolling
Stage III Colon Cancer
Drug: mFOLFOX6 3-6 month
Device: Signatera test

Phase 2, Phase 3

NRG Oncology
NRG Oncology

Saint Louis, Missouri, United States and 899 other locations

tolerability, drug levels, molecular effects, and clinical activity of MRTX849 in combination with TNO155 in patients with advanced solid tumors...

Active, not recruiting
Metastatic Cancer
Advanced Cancer
Drug: TNO155
Drug: MRTX849

Phase 1

Mirati Therapeutics
Mirati Therapeutics

Saint Louis, Missouri, United States and 11 other locations

treatment of minimal residual disease (MRD) in subjects with KRAS/neuroblastoma ras viral oncogene homolog (NRAS) mutated PDAC or other solid tumors...

Active, not recruiting
Ovarian Cancer
Bile Duct Cancer
Drug: ELI-002 2P

Phase 1

Elicio Therapeutics
Elicio Therapeutics

Saint Louis, Missouri, United States and 9 other locations

The goal of this study is to test A2B694, an autologous logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorec...

Enrolling
Ovarian Neoplasms
Solid Tumor, Adult
Diagnostic Test: xT CDx with HLA-LOH Assay
Biological: A2B694

Phase 1, Phase 2

A2 Biotherapeutics

St. Louis, Missouri, United States and 9 other locations

The goal of this study is to test A2B395, an allogeneic logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorec...

Begins enrollment in 4 months
Solid Tumor, Adult
Colon Cancer
Biological: A2B395
Diagnostic Test: xT CDx with HLA-LOH assay

Phase 1, Phase 2

A2 Biotherapeutics

Saint Louis, Missouri, United States and 5 other locations

Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET amplification, solid tumors harboring MET...

Enrolling
Brain Tumor
Colon Cancer
Drug: APL-101 Oral Capsules

Phase 2

Apollomics

Saint Louis, Missouri, United States and 90 other locations

in each subject population expansion cohort of advanced solid tumors that harbor a ROS1, NTRK1, NTRK2, or NTRK3 gene rearrangement. The seco...

Enrolling
Locally Advanced Solid Tumors
Metastatic Solid Tumors
Drug: Oral repotrectinib (TPX-0005)

Phase 1, Phase 2

Turning Point Therapeutics
Turning Point Therapeutics

Saint Louis, Missouri, United States and 148 other locations

with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...

Active, not recruiting
Neoplasms
Drug: Cetuximab
Drug: Oxaliplatin

Phase 3

Pfizer
Pfizer

Saint Louis, Missouri, United States and 409 other locations

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