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(SOC) in participants with untreated T4N0 or Stage III (resectable), defective mismatch repair/ microsatellite instability high (dMMR/MSI-H) colon...
Phase 3
Saint Louis, Missouri, United States and 249 other locations
This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...
Phase 1, Phase 2
Saint Louis, Missouri, United States and 84 other locations
This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...
Phase 2, Phase 3
Saint Louis, Missouri, United States and 987 other locations
treatment of minimal residual disease (MRD) in subjects with KRAS/neuroblastoma ras viral oncogene homolog (NRAS) mutated PDAC or other solid tumors...
Phase 1
Saint Louis, Missouri, United States and 9 other locations
The goal of this study is to test A2B694, an autologous logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorec...
Phase 1, Phase 2
St. Louis, Missouri, United States and 10 other locations
The goal of this study is to test A2B395, an allogeneic logic-gated Tmod™ CAR T-cell product in subjects with solid tumors including colorec...
Phase 1, Phase 2
St. Louis, Missouri, United States and 8 other locations
in very high numbers).This includes (but limited to) the following cancer types:Non-Small Cell Lung Cancer (NSCLC): It's a type of ...
Phase 1
Saint Louis, Missouri, United States and 25 other locations
with standard chemotherapy for the potential treatment of colorectal cancer that:* has spread to other parts of the body (metastatic);* has ...
Phase 3
Saint Louis, Missouri, United States and 274 other locations
in each subject population expansion cohort of advanced solid tumors that harbor a ROS1, NTRK1, NTRK2, or NTRK3 gene rearrangement. The seco...
Phase 1, Phase 2
Saint Louis, Missouri, United States and 165 other locations
a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon...
Phase 3
Saint Louis, Missouri, United States and 989 other locations
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