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and Nivolumab. Researchers want to find out if this combination of Regorafenib and Nivolumab can help people with metastatic colorectal cancer...
Phase 1
Tampa, Florida, United States
The purpose of the study is to determine the feasibility of using magnetic resonance imaging (MRI)-guided adaptive chemoradiation therapy to improve...
Early Phase 1
Tampa, Florida, United States
with panitumumab in subjects with unresectable, refractory, KRAS/NRAS/BRAF wild-type, microsatellite stable (MSS) metastatic colorectal cancer...
Phase 2
Tampa, Florida, United States and 4 other locations
the efficacy of CTX-009 in patients with metastatic colorectal cancer.A Simon Two-Stage adaptive design will enroll approximately 37 patient...
Phase 2
Saint Petersburg, Florida, United States and 6 other locations
to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...
Phase 1, Phase 2
Pembroke, Florida, United States and 83 other locations
the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...
Phase 2, Phase 3
Tampa, Florida, United States and 827 other locations
Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary antitumor activity of CO...
Phase 1
Sarasota, Florida, United States and 8 other locations
A Phase 1/2 Open-label, Multi-center Study of the Safety, Pharmacokinetics, and Anti-tumor Activity of LYT-200 Alone and in Combination with Chemothe...
Phase 1, Phase 2
Sarasota, Florida, United States and 11 other locations
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of escalating doses of RMC-6291 (KRAS G12C(ON) inhibitor...
Phase 1
Tampa, Florida, United States and 63 other locations
plus BSC in participants with refractory metastatic colorectal cancer (mCRC). 691 participants were randomized to one of the following treat...
Phase 3
Saint Petersburg, Florida, United States and 152 other locations
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