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and pembrolizumab, before surgery can treat a common type of colon cancer called microsatellite stable (MSS) colon cancer...
Phase 2
Tampa, Florida, United States and 29 other locations
The purpose of the study is to determine the feasibility of using magnetic resonance imaging (MRI)-guided adaptive chemoradiation therapy to improve...
Early Phase 1
Tampa, Florida, United States
to participants with advanced solid tumors, including rearranged during transfection (RET)-fusion-positive solid tumors, medullary thyroid cancer...
Phase 1, Phase 2
Pembroke, Florida, United States and 85 other locations
This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant sol...
Phase 1
Tampa, Florida, United States and 16 other locations
the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon...
Phase 2, Phase 3
Tampa, Florida, United States and 1076 other locations
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.
Phase 1, Phase 2
Tampa, Florida, United States and 20 other locations
This is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced Cancer...
Phase 1, Phase 2
Tampa, Florida, United States and 13 other locations
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of escalating doses of RMC-6291 (KRAS G12C(ON) inhibitor...
Phase 1
Tampa, Florida, United States and 63 other locations
This study is to evaluate the safety, tolerability, and PK profiles of Elironrasib and Daraxonrasib as monotherapies and combination therapy in patie...
Phase 1, Phase 2
Tampa, Florida, United States and 55 other locations
PRE-ISPY Phase I/II (I-SPY-P1) is an open-label, multisite platform study with multiple ongoing drug regimen arms added by protocol amendment which i...
Phase 1, Phase 2
Tampa, Florida, United States and 9 other locations
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