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The purpose of the study is to determine the feasibility of using magnetic resonance imaging (MRI)-guided adaptive chemoradiation therapy to improve...
Early Phase 1
Tampa, Florida, United States
This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor ...
Phase 1, Phase 2
Pembroke, Florida, United States and 84 other locations
is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors...
Phase 1
Tampa, Florida, United States and 16 other locations
Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors....
Phase 1
Tampa, Florida, United States and 15 other locations
the efficacy of CTX-009 in patients with metastatic colorectal cancer.A Simon Two-Stage adaptive design will enroll approximately 37 patient...
Phase 2
Saint Petersburg, Florida, United States and 6 other locations
This study is to evaluate the safety, tolerability, and PK profiles of RMC-6291 and RMC-6236 in adults with KRAS G12C-mutated solid tumors....
Phase 1
Tampa, Florida, United States and 53 other locations
This study will test the safety of a drug called PF-08046052/SGN-EGFRd2 in participants with advanced solid tumors. It will also study the s...
Phase 1
Tampa, Florida, United States and 12 other locations
inhibitor) monotherapy in adult subjects with advanced solid tumors and to identify the maximum tolerated dose (MTD), and the recommended Ph...
Phase 1
Tampa, Florida, United States and 63 other locations
Phase 1 open label sequential dose escalation and cohort expansion study evaluating the safety, tolerability and preliminary antitumor activity of CO...
Phase 1
Sarasota, Florida, United States and 8 other locations
This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor...
Phase 2, Phase 3
Tampa, Florida, United States and 939 other locations
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