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Find clinical trials for Diabetes in Pittsburgh, PA

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Related conditions:

Diabetes Mellitus
Type 2 Diabetes Mellitus
Type 1 Diabetes Mellitus
Diabetic Foot
Foot Ulcer
Obesity
Ulcer

Diabetes trials near Pittsburgh, PA, USA:

A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell Function

Objectives The objective of this clinical trial is to assess whether ladarixin treatment has an effect to preserve β-cell function and delay the prog...

Active, not recruiting
Recent Onset type1 Diabetes
Drug: Placebo
Drug: Ladarixin

Phase 2

Dompé
Dompé

Pittsburgh, Pennsylvania, United States and 56 other locations

Hepatic and Cardiovascular endpoints for patients with Type 2 Diabetes who are inadequately controlled on one or more glucose lowering agent...

Enrolling
Type 2 Diabetes
Device: Duodenal Mucosal Resurfacing (Sham)
Device: Duodenal Mucosal Resurfacing (DMR)
Fractyl Health

Pittsburgh, Pennsylvania, United States and 64 other locations

This study will evaluate the safety, efficacy and durability of SR-02 administered to the omentum of patients of Type 1 diabetes with severe...

Begins enrollment in 1 month
Diabetes Mellitus Type 1
Biological: Allogeneic Pancreatic Endocrine Cell Clusters

Phase 1, Phase 2

Seraxis

Pittsburgh, Pennsylvania, United States and 1 other location

This study aims to investigate the efficacy and safety of tirzepatide in participants with type 2 diabetes (T2D) compared to other existing ...

Active, not recruiting
Type 2 Diabetes
Drug: Antihyperglycemic medication
Drug: Tirzepatide

Phase 4

Lilly
Lilly

Uniontown, Pennsylvania, United States and 89 other locations

The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes...

Enrolling
Type 2 Diabetes
Drug: Retatrutide
Drug: Placebo

Phase 3

Lilly
Lilly

Pittsburgh, Pennsylvania, United States and 61 other locations

control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes...

Enrolling
Diabetes Mellitus, Type 1
Drug: Ritlecitinib
Drug: Abrocitinib 200 MG Oral Tablet

Phase 2

National Institutes of Health (NIH)
National Institutes of Health (NIH)

Pittsburgh, Pennsylvania, United States and 19 other locations

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increas...

Active, not recruiting
Type 2 Diabetes Mellitus
Drug: Tirzepatide
Drug: Dulaglutide

Phase 3

Lilly
Lilly

Pittsburgh, Pennsylvania, United States and 654 other locations

The purpose of the study is to evaluate the safety, tolerability, and efficacy of VX-264 in participants with type 1 diabetes (T1D)....

Enrolling
Type 1 Diabetes
Drug: VX-264

Phase 1, Phase 2

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 15 other locations

the treatment with the COMS One device in subjects with refractory diabetic foot ulcers (DFUs). The prospective randomized, double-blinded, ...

Enrolling
Diabetic Foot Ulcer
Device: COMS One device
Device: Sham device
Piomic Medical

McKeesport, Pennsylvania, United States and 22 other locations

This study will evaluate the safety, tolerability and efficacy of VX-880 infusion in participants with Type 1 diabetes (T1D) and impaired aw...

Enrolling
Diabetes Mellitus, Type 1
Impaired Hypoglycemic Awareness
Biological: VX-880

Phase 3

Vertex Pharmaceuticals
Vertex Pharmaceuticals

Pittsburgh, Pennsylvania, United States and 22 other locations

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