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Find clinical trials for Glioblastoma (GBM) in Birmingham, AL

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Related conditions:

Glioblastoma
Brain Cancer
Glioma
Cancer
Recurrence
Astrocytoma
Gliosarcoma

Glioblastoma (GBM) trials near Birmingham, AL, USA:

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM (FRONTIER)

FRONTIER Study is a prospective, interventional, single-arm, multi-center, study to assess the safety and technical feasibility of TheraSphere GBM...

Enrolling
Recurrent Glioblastoma
Glioblastoma Multiforme
Device: TheraSphere GBM

Phase 1

Boston Scientific
Boston Scientific

Birmingham, Alabama, United States and 8 other locations

Locations recently updated

The purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma...

Enrolling
Glioblastoma (GBM)
Newly Diagnosed Glioblastoma
Drug: temozolomide (TMZ)
Drug: silevertinib in combination with temozolomide

Phase 2

Black Diamond Therapeutics

Birmingham, Alabama, United States and 23 other locations

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II...

Enrolling
Glioblastoma
Drug: Regorafenib
Drug: Temozolomide

Phase 2, Phase 3

Global Coalition for Adaptive Research

Birmingham, Alabama, United States and 62 other locations

the return of cancer in patients with a newly diagnosed or recurrent glioblastoma multiforme (GBM) in combination with standard che...

Active, not recruiting
Glioblastoma
Biological: Allogeneic genetically modified gamma-delta T cells
Biological: Autologous genetically modified gamma-delta T cells

Phase 1, Phase 2

In8bio

Birmingham, Alabama, United States and 4 other locations

This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...

Enrolling
Glioblastoma
Drug: Neratinib
Drug: CC-115

Phase 2

Patrick Wen, MD

Birmingham, Alabama, United States and 11 other locations

growth factor receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM...

Active, not recruiting
Advanced Non-Small Cell Squamous Lung Cancer
Epidermal Growth Factor Receptor C797S
Drug: silevertinib (BDTX-1535) monotherapy

Phase 1, Phase 2

Black Diamond Therapeutics

Birmingham, Alabama, United States and 28 other locations

The purpose of this study is to establish the recommended phase 2 dose of eflornithine in combination with temozolomide in patients whose glioblastoma...

Enrolling
Glioblastoma
Glioblastoma Multiforme
Drug: Temozolomide
Drug: Eflornithine (Dose Level 2)

Phase 1

Orbus Therapeutics

Birmingham, Alabama, United States and 7 other locations

(TMZ) in adult participants with newly-diagnosed, MGMT unmethylated glioblastoma multiforme (GBM). The main question it aims to ans...

Active, not recruiting
Glioblastoma
GBM
Drug: Niraparib
Drug: Temozolomide

Phase 3

Ivy Brain Tumor Center

Birmingham, Alabama, United States and 94 other locations

The study treatment, BAY 3713372, is under development to treat MTAP (methylthioadenosine phosphorylase)-deleted solid tumors. It is thought to work...

Enrolling
MTAP-deleted Solid Tumors
Drug: BAY 3713372

Phase 1, Phase 2

Bayer
Bayer

Birmingham, Alabama, United States and 59 other locations

therapy is safe to administer to patients with a newly diagnosed glioblastoma multiforme (GBM) in combination with temozolomide (TM...

Active, not recruiting
Brain Tumor Adult
Biological: DRI cell therapy

Phase 1

The University of Alabama at Birmingham
The University of Alabama at Birmingham

Birmingham, Alabama, United States

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