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Find clinical trials for Glioblastoma (GBM) in Chicago, IL

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Related conditions:

Glioblastoma
Recurrence
Glioma
Brain Cancer
Astrocytoma
Cancer
Gliosarcoma

Glioblastoma (GBM) trials near Chicago, IL, USA:

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM (FRONTIER)

FRONTIER Study is a prospective, interventional, single-arm, multi-center, study to assess the safety and technical feasibility of TheraSphere GBM...

Enrolling
Recurrent Glioblastoma
Glioblastoma Multiforme
Device: TheraSphere GBM

Early Phase 1

Boston Scientific
Boston Scientific

Chicago, Illinois, United States and 4 other locations

The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: Dendritic cell immunotherapy

Phase 3

Northwest Biotherapeutics
Northwest Biotherapeutics

Chicago, Illinois, United States and 85 other locations

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting
Glioblastoma
Adult-type Diffuse Gliomas
Drug: Pemigatinib

Phase 2

Incyte
Incyte

Chicago, Illinois, United States and 80 other locations

The purpose of this study is to evaluate patients with glioblastoma that is MGMT-methylated (the MGMT gene is altered by a chemical change)....

Active, not recruiting
Brain Neoplasms
Other: Nivolumab Placebo
Drug: Nivolumab

Phase 3

Bristol-Myers Squibb (BMS)
Bristol-Myers Squibb (BMS)

Chicago, Illinois, United States and 122 other locations

are also impermeable to the passage of therapeutic molecules from the blood to the brain. The development of effective treatments against glioblastoma...

Enrolling
Glioblastoma
Recurrent Glioblastoma
Device: SonoCloud-9 (SC9)
Drug: Carboplatin

Phase 3

Carthera

Chicago, Illinois, United States and 9 other locations

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting
Glioblastoma Multiforme
Device: Optune®
NovoCure
NovoCure

Chicago, Illinois, United States and 132 other locations

Paclitaxel is among the most active agents against glioblastoma in preclinical models. However, its clinical use has been hampered by the bl...

Enrolling
Glioblastoma
Recurrent Glioblastoma
Drug: Chemotherapy, carboplatin
Drug: Chemotherapy, albumin-bound paclitaxel

Phase 1, Phase 2

Northwestern University
Northwestern University

Chicago, Illinois, United States

This is an open-label, two-part, phase 1-2 dose-finding study designed to determine the safety, tolerability, PK, PD, and proof-of-concept efficacy o...

Enrolling
Glioblastoma
Glioblastoma Multiforme
Drug: Temozolomide
Drug: ST101

Phase 1, Phase 2

Sapience Therapeutics

Warrenville, Illinois, United States and 11 other locations

progression-free survival (PFS) of patients with newly diagnosed glioblastoma multiforme (GBM) can be improved by the addition of i...

Enrolling
Glioblastoma
Radiation: Radiochemotherapy
Procedure: Standard surgery

Phase 3

Universitätsmedizin Mannheim

Maywood, Illinois, United States and 18 other locations

This is an open-label, multicenter, randomized, parallel, 2-arm, efficacy and safety study. Patients with GBM after failure of standard firs...

Active, not recruiting
Glioblastoma Multiforme, Adult
Drug: Berubicin
Drug: Lomustine

Phase 2

CNS Pharmaceuticals
CNS Pharmaceuticals

Chicago, Illinois, United States and 55 other locations

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