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Find clinical trials for Glioblastoma (GBM) in Chicago, IL

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Related conditions:

Glioblastoma
Recurrence
Glioma
Brain Cancer
Cancer
Astrocytoma
Gliosarcoma

Glioblastoma (GBM) trials near Chicago, IL, USA:

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM (FRONTIER)

FRONTIER Study is a prospective, interventional, single-arm, multi-center, study to assess the safety and technical feasibility of TheraSphere GBM...

Enrolling
Recurrent Glioblastoma
Glioblastoma Multiforme
Device: TheraSphere GBM

Early Phase 1

Boston Scientific
Boston Scientific

Chicago, Illinois, United States and 4 other locations

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting
Glioblastoma
Adult-type Diffuse Gliomas
Drug: Pemigatinib

Phase 2

Incyte
Incyte

Chicago, Illinois, United States and 80 other locations

are also impermeable to the passage of therapeutic molecules from the blood to the brain. The development of effective treatments against glioblastoma...

Enrolling
Glioblastoma
Recurrent Glioblastoma
Device: SonoCloud-9 (SC9)
Drug: Temozolomide

Phase 3

Carthera

Chicago, Illinois, United States and 22 other locations

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting
Glioblastoma Multiforme
Device: Optune®
NovoCure
NovoCure

Chicago, Illinois, United States and 132 other locations

receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM) expr...

Enrolling
Advanced Non-Small Cell Squamous Lung Cancer
Epidermal Growth Factor Receptor C797S
Drug: BDTX-1535 monotherapy

Phase 1, Phase 2

Black Diamond Therapeutics

Chicago, Illinois, United States and 24 other locations

Paclitaxel is among the most active agents against glioblastoma in preclinical models. However, its clinical use has been hampered by the bl...

Enrolling
Glioblastoma
Recurrent Glioblastoma
Drug: Chemotherapy, carboplatin
Drug: Chemotherapy, albumin-bound paclitaxel

Phase 1, Phase 2

Northwestern University
Northwestern University

Chicago, Illinois, United States

This is an open-label, two-part, phase 1-2 dose-finding study designed to determine the safety, tolerability, PK, PD, and proof-of-concept efficacy o...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: ST101
Drug: Temozolomide

Phase 1, Phase 2

Sapience Therapeutics

Warrenville, Illinois, United States and 10 other locations

Locations recently updated

This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an...

Enrolling
Locally Advanced Solid Tumor
Drug: TNG908

Phase 1, Phase 2

Tango Therapeutics
Tango Therapeutics

Chicago, Illinois, United States and 18 other locations

progression-free survival (PFS) of patients with newly diagnosed glioblastoma multiforme (GBM) can be improved by the addition of i...

Active, not recruiting
Glioblastoma
Procedure: Standard surgery
Drug: Temozolomide

Phase 3

Universitätsmedizin Mannheim

Maywood, Illinois, United States and 18 other locations

This is an open-label, multicenter, randomized, parallel, 2-arm, efficacy and safety study. Patients with GBM after failure of standard firs...

Active, not recruiting
Glioblastoma Multiforme, Adult
Drug: Berubicin
Drug: Lomustine

Phase 2

CNS Pharmaceuticals
CNS Pharmaceuticals

Chicago, Illinois, United States and 47 other locations

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