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efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...
Phase 1, Phase 2
Houston, Texas, United States and 20 other locations
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....
Phase 2, Phase 3
Houston, Texas, United States and 61 other locations
of O-6-methylguanine-DNA methyltransferase (MGMT) unmethylated glioblastoma with VAL-083 improves overall survival (OS), compared to histori...
Phase 2
Houston, Texas, United States
This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...
Phase 2
Houston, Texas, United States and 80 other locations
This phase I trial studies best dose and side effects of oncolytic adenovirus DNX-2401 in treating patients with high-grade glioma that has come back...
Phase 1
Houston, Texas, United States
and tolerability of these combinations in adult participants with glioblastoma (GBM). Arm B which was previously added to the proto...
Phase 1, Phase 2
Houston, Texas, United States and 11 other locations
This research study is studying a targeted therapy as a possible treatment for recurrent glioblastoma (GBM).The following intervent...
Phase 2
Houston, Texas, United States and 6 other locations
The purpose of this first-in-human (FIH) study of \[177Lu\]-NeoB is to characterize the safety, tolerability, pharmacokinetics (PK) as well as the di...
Phase 1, Phase 2
Houston, Texas, United States and 13 other locations
This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...
Phase 2
Houston, Texas, United States and 11 other locations
are also impermeable to the passage of therapeutic molecules from the blood to the brain. The development of effective treatments against glioblastoma...
Phase 3
Houston, Texas, United States and 22 other locations
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