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Find clinical trials for Glioblastoma (GBM) in Houston, TX

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Related conditions:

Glioblastoma
Recurrence
Brain Cancer
Glioma
Cancer
Astrocytoma
Gliosarcoma

Glioblastoma (GBM) trials near Houston, TX, USA:

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...

Active, not recruiting
Glioblastoma
Drug: Temozolomide
Biological: INO-9012

Phase 1, Phase 2

Inovio Pharmaceuticals
Inovio Pharmaceuticals

Houston, Texas, United States and 20 other locations

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling
Glioblastoma
Drug: Temozolomide
Radiation: Radiation

Phase 2, Phase 3

Global Coalition for Adaptive Research

Houston, Texas, United States and 61 other locations

of O-6-methylguanine-DNA methyltransferase (MGMT) unmethylated glioblastoma with VAL-083 improves overall survival (OS), compared to histori...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: VAL-083, Dianhydrogalactitol

Phase 2

Kintara Therapeutics

Houston, Texas, United States

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting
Glioblastoma
Adult-type Diffuse Gliomas
Drug: Pemigatinib

Phase 2

Incyte
Incyte

Houston, Texas, United States and 80 other locations

This phase I trial studies best dose and side effects of oncolytic adenovirus DNX-2401 in treating patients with high-grade glioma that has come back...

Enrolling
Recurrent Glioblastoma
IDH1 wt Allele
Biological: Oncolytic Adenovirus Ad5-DNX-2401
Procedure: Therapeutic Conventional Surgery

Phase 1

M.D. Anderson Cancer Center
M.D. Anderson Cancer Center

Houston, Texas, United States

and tolerability of these combinations in adult participants with glioblastoma (GBM). Arm B which was previously added to the proto...

Enrolling
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Astrocytoma, Grade III
Drug: Debio 0123
Drug: Temozolomide

Phase 1, Phase 2

Debiopharm
Debiopharm

Houston, Texas, United States and 11 other locations

This research study is studying a targeted therapy as a possible treatment for recurrent glioblastoma (GBM).The following intervent...

Active, not recruiting
Glioblastoma
Procedure: Surgery
Drug: Abemaciclib

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Houston, Texas, United States and 6 other locations

The purpose of this first-in-human (FIH) study of \[177Lu\]-NeoB is to characterize the safety, tolerability, pharmacokinetics (PK) as well as the di...

Enrolling
Neoplasms
Drug: [68Ga]-NeoB
Drug: LCZ696

Phase 1, Phase 2

Advanced Accelerator Applications

Houston, Texas, United States and 13 other locations

This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...

Enrolling
Glioblastoma
Drug: Neratinib
Drug: Temozolomide

Phase 2

Patrick Wen, MD

Houston, Texas, United States and 11 other locations

are also impermeable to the passage of therapeutic molecules from the blood to the brain. The development of effective treatments against glioblastoma...

Enrolling
Glioblastoma
Recurrent Glioblastoma
Device: SonoCloud-9 (SC9)
Drug: Temozolomide

Phase 3

Carthera

Houston, Texas, United States and 22 other locations

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