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Find clinical trials for Glioblastoma (GBM) in Houston, TX

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Related conditions:

Glioblastoma
Recurrence
Brain Cancer
Glioma
Astrocytoma
Cancer
Gliosarcoma

Glioblastoma (GBM) trials near Houston, TX, USA:

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...

Active, not recruiting
Glioblastoma
Drug: Temozolomide
Biological: INO-5401

Phase 1, Phase 2

Inovio Pharmaceuticals
Inovio Pharmaceuticals

Houston, Texas, United States and 20 other locations

The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: Dendritic cell immunotherapy

Phase 3

Northwest Biotherapeutics
Northwest Biotherapeutics

Houston, Texas, United States and 85 other locations

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling
Glioblastoma
Drug: Temozolomide
Radiation: Radiation

Phase 2, Phase 3

Global Coalition for Adaptive Research

Houston, Texas, United States and 61 other locations

of O-6-methylguanine-DNA methyltransferase (MGMT) unmethylated glioblastoma with VAL-083 improves overall survival (OS), compared to histori...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: VAL-083, Dianhydrogalactitol

Phase 2

Kintara Therapeutics

Houston, Texas, United States

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting
Glioblastoma
Adult-type Diffuse Gliomas
Drug: Pemigatinib

Phase 2

Incyte
Incyte

Houston, Texas, United States and 80 other locations

and tolerability of these combinations in adult participants with glioblastoma (GBM).The primary purpose of Phase 2 of this study is...

Enrolling
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype
Astrocytoma, Grade III
Radiation: Radiotherapy
Drug: Debio 0123

Phase 1, Phase 2

Debiopharm
Debiopharm

Houston, Texas, United States and 9 other locations

This phase I trial studies best dose and side effects of oncolytic adenovirus DNX-2401 in treating patients with high-grade glioma that has come back...

Enrolling
Recurrent Glioblastoma
IDH1 wt Allele
Procedure: Therapeutic Conventional Surgery
Biological: Oncolytic Adenovirus Ad5-DNX-2401

Phase 1

M.D. Anderson Cancer Center
M.D. Anderson Cancer Center

Houston, Texas, United States

This research study is studying a targeted therapy as a possible treatment for recurrent glioblastoma (GBM).The following intervent...

Active, not recruiting
Glioblastoma
Procedure: Surgery
Drug: Abemaciclib

Phase 2

Dana-Farber Cancer Institute
Dana-Farber Cancer Institute

Houston, Texas, United States and 6 other locations

This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM).The drugs involved in ...

Enrolling
Glioblastoma
Drug: Neratinib
Drug: Temozolomide

Phase 2

Patrick Wen, MD

Houston, Texas, United States and 11 other locations

The purpose of this first-in-human (FIH) study of \[177Lu\]-NeoB is to characterize the safety, tolerability, pharmacokinetics (PK) as well as the di...

Enrolling
Neoplasms
Drug: LCZ696
Drug: [177Lu]-NeoB

Phase 1, Phase 2

Advanced Accelerator Applications

Houston, Texas, United States and 13 other locations

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