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Find clinical trials for Glioblastoma (GBM) in London, England

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Related conditions:

Glioblastoma
Recurrence
Brain Cancer
Glioma
Astrocytoma
Cancer
Gliosarcoma

Glioblastoma (GBM) trials near London, England, GBR:

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer

The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: Dendritic cell immunotherapy

Phase 3

Northwest Biotherapeutics
Northwest Biotherapeutics

London, Greater London, United Kingdom and 85 other locations

placebo-controlled, randomised trial to compare the cannabinoid Nabiximols with placebo in patients with recurrent MGMT methylated glioblastoma...

Enrolling
Glioblastoma
Brain Tumor, Recurrent
Drug: Nabiximols-matched placebo
Drug: Nabiximols

Phase 2

University of Birmingham

London, United Kingdom and 19 other locations

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting
Glioblastoma
Adult-type Diffuse Gliomas
Drug: Pemigatinib

Phase 2

Incyte
Incyte

London, United Kingdom and 80 other locations

The purpose of this first-in-human (FIH) study of \[177Lu\]-NeoB is to characterize the safety, tolerability, pharmacokinetics (PK) as well as the di...

Enrolling
Neoplasms
Drug: LCZ696
Drug: [177Lu]-NeoB

Phase 1, Phase 2

Advanced Accelerator Applications

Cambridge, United Kingdom and 13 other locations

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting
Glioblastoma Multiforme
Device: Optune®
NovoCure
NovoCure

London, United Kingdom and 132 other locations

(TNBC), ovarian cancer, gastric cancer, colorectal cancer (CRC), glioblastoma (GBM), biliary tract cancers (BTC), or pancreatic can...

Active, not recruiting
Glioblastoma
Gastric Cancer
Biological: Pembrolizumab
Drug: Lenvatinib

Phase 2

Merck Sharp & Dohme (MSD)
Merck Sharp & Dohme (MSD)

London, London, City Of, United Kingdom and 87 other locations

This is an open-label, two-part, phase 1-2 dose-finding study designed to determine the safety, tolerability, PK, PD, and proof-of-concept efficacy o...

Enrolling
Glioblastoma
Glioblastoma Multiforme
Drug: Temozolomide
Drug: ST101

Phase 1, Phase 2

Sapience Therapeutics

London, United Kingdom and 11 other locations

This study will test an investigational drug called AZD1390 in combination with radiation therapy for the treatment of brain tumors. This is the firs...

Enrolling
Recurrent Glioblastoma Multiforme
Primary Glioblastoma Multiforme
Drug: AZD1390
Radiation: Radiation Therapy

Phase 1

AstraZeneca
AstraZeneca

London, United Kingdom and 8 other locations

This is a single centre, proof-of-concept phase I trial of atezolizumab in combination with ipatasertib. There are two parts to this study, the dose...

Enrolling
Glioblastoma Multiforme
Solid Tumor
Drug: ipatasertib
Drug: Atezolizumab

Phase 1, Phase 2

Institute of Cancer Research, United Kingdom

Sutton, Surrey, United Kingdom

Researchers are looking for a better way to treat people with solid tumors. Before a treatment can be approved for people to take, researchers do cli...

Active, not recruiting
Solid Tumors
Drug: Regorafenib, (Stivarga, BAY73-4506)
Drug: Nivolumab (Opdivo)

Phase 2

Bayer
Bayer

London, United Kingdom and 33 other locations

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