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Find clinical trials for Glioblastoma (GBM) in Los Angeles, CA

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Related conditions:

Glioblastoma
Brain Cancer
Glioma
Cancer
Recurrence
Astrocytoma
Gliosarcoma

Glioblastoma (GBM) trials near Los Angeles, CA, USA:

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...

Active, not recruiting
Glioblastoma
Drug: Temozolomide
Biological: INO-9012

Phase 1, Phase 2

Inovio Pharmaceuticals
Inovio Pharmaceuticals

Duarte, California, United States and 20 other locations

(SOC) will improve survival in adult patients newly diagnosed with glioblastoma (IDH-wt). It will also evaluate the safety of DOC1021 + pIFN...

Enrolling
Glioblastoma (GBM)
Drug: Temodar (Temozolomide)
Biological: DOC1021

Phase 2

Diakonos Oncology Corporation

Duarte, California, United States and 15 other locations

A Phase 1b/2, Multicenter, Open-Label Study of ACP-196 in Subjects with Recurrent Glioblastoma Multiforme (GBM)...

Active, not recruiting
Glioblastoma Multiforme
Drug: ACP-196

Phase 1, Phase 2

Acerta Pharma
Acerta Pharma

Los Angeles, California, United States and 6 other locations

The purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma...

Enrolling
Glioblastoma (GBM)
Newly Diagnosed Glioblastoma
Drug: temozolomide (TMZ)
Drug: silevertinib in combination with temozolomide

Phase 2

Black Diamond Therapeutics

Los Angeles, California, United States of America and 7 other locations

In summary, standard of care postoperative chemoradiation for patients with newly diagnosed GBM does not routinely provide durable local con...

Active, not recruiting
Glioblastoma
Device: Surgical tumor resection, GammaTile radiation therapy implantation, Stupp protocol (EBRT and Temozolamide)

Phase 4

GT Medical Technologies

Los Angeles, California, United States and 15 other locations

This study will investigate different doses of \[177Lu\]Lu-NeoB in combination with RT and TMZ in participants with newly diagnosed glioblastoma...

Active, not recruiting
Newly Diagnosed and Recurrent Glioblastoma
Other: Temozolomide
Drug: [68Ga]Ga-NeoB

Phase 1

Novartis
Novartis

Los Angeles, California, United States and 15 other locations

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II...

Enrolling
Glioblastoma
Drug: Regorafenib
Drug: Temozolomide

Phase 2, Phase 3

Global Coalition for Adaptive Research

Los Angeles, California, United States and 62 other locations

therapy alone as a treatment for newly diagnosed MGMT unmethylated glioblastoma patients. The patients' own cancer cells collected after sur...

Active, not recruiting
Glioblastoma Multiforme of Brain
Radiation: Radiotherapy
Procedure: Standard of Care

Phase 2, Phase 3

TVAX Biomedical

Los Angeles, California, United States and 7 other locations

with ipilimumab and surgery when used in the treatment of recurrent glioblastoma.The names of the study drugs involved in this study are:* N...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: Ipilimumab-Placebo
Drug: Nivolumab-Placebo

Phase 1

Patrick Wen, MD

Los Angeles, California, United States and 3 other locations

Optune® together with maintenance TMZ and placebo in newly diagnosed Glioblastoma (GBM) patients. The primary objective of the stud...

Enrolling
Glioblastoma
Drug: Temozolomide
Drug: Placebo

Phase 3

NovoCure
NovoCure

Los Angeles, California, United States and 90 other locations

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