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as a monotherapy in participants with newly diagnosed or recurrent epidermal growth factor receptor variant III (EGFRvIII)-positive glioblastoma...
Phase 1
Madrid, Spain and 8 other locations
and tolerability of these combinations in adult participants with glioblastoma (GBM). Arm B which was previously added to the proto...
Phase 1, Phase 2
Madrid, Spain and 14 other locations
are also impermeable to the passage of therapeutic molecules from the blood to the brain. The development of effective treatments against glioblastoma...
Phase 3
Madrid, Spain and 38 other locations
A Dose Finding Study of \[177Lu\]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination with Standard of Care and in Recurrent Glioblastoma...
Phase 1
Madrid, Spain and 14 other locations
(TMZ) in adult participants with newly-diagnosed, MGMT unmethylated glioblastoma multiforme (GBM). The main questions it aims to an...
Phase 3
Madrid, Spain and 23 other locations
This study will investigate different doses of \[177Lu\]Lu-NeoB in combination with RT and TMZ in participants with newly diagnosed glioblastoma...
Phase 1
Madrid, Spain and 18 other locations
The goal of this interventional study is to determine the strength of cobolimab and dostarlimab that is most tolerated in children and young adults w...
Phase 1, Phase 2
Madrid, Spain and 10 other locations
used as adjuvant treatment in patients with newly diagnosed GBM who are MGMT unmethylated and have completed concomitant treatment with temo...
Early Phase 1
Madrid, Spain and 4 other locations
This is an open-label, multicenter, randomized, parallel, 2-arm, efficacy and safety study. Patients with GBM after failure of standard firs...
Phase 2
Madrid, Spain and 47 other locations
The proposed Phase IIB/III randomized, double-blind, placebo-controlled trial in subjects with newly diagnosed primary glioblastoma multifor...
Phase 2, Phase 3
Madrid, Spain and 21 other locations
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