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This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...
Phase 2
Milano, Italy and 80 other locations
The purpose of this study is to evaluate patients with glioblastoma that is MGMT-methylated (the MGMT gene is altered by a chemical change)....
Phase 3
Milano, Italy and 122 other locations
(TNBC), ovarian cancer, gastric cancer, colorectal cancer (CRC), glioblastoma (GBM), biliary tract cancers (BTC), or pancreatic can...
Phase 2
Rozzano, Milano, Italy and 87 other locations
The PhAST Trial is an adaptive first-in-human clinical trial of the acetylglucosaminyltransferase V inhibitor PhOx430 in patients with advanced solid...
Phase 1
Milano, Italy and 1 other location
dd-TMZ "one week on, one week off" in patients affected by recurrent GBM IDH wild-type and recurrent IDH mutant (WHO grade 2-4) gliomas.The ...
Phase 1, Phase 2
Rozzano, Mi, Italy
with a lentiviral vector driving myeloid specific interferon-alpha2 expression, which will be administered to up to 27 patients affected by GBM...
Phase 1, Phase 2
Milan, Italy and 2 other locations
Researchers are looking for a better way to treat people with solid tumors. Before a treatment can be approved for people to take, researchers do cli...
Phase 2
Milano, Lombardia, Italy and 33 other locations
when combined with standard of care treatment, temozolomide (TMZ) with or without radiotherapy (RT) in the newly diagnosed WHO Grade IV glioblastoma...
Phase 1
Milan, Italy and 28 other locations
This is an open-label, multicenter, randomized, parallel, 2-arm, efficacy and safety study. Patients with GBM after failure of standard firs...
Phase 2
Milan, Italy and 55 other locations
The proposed Phase IIB/III randomized, double-blind, placebo-controlled trial in subjects with newly diagnosed primary glioblastoma multifor...
Phase 2, Phase 3
Milan, Italy and 21 other locations
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