Find clinical trials for Glioblastoma (GBM) in Paris, Île-de-France

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Glioblastoma (GBM) trials near Paris, Île-de-France, FRA:

Locations recently updated

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma (GBM AGILE)

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling

Glioblastoma

Biological: ADI-PEG 20

Drug: VT1021

Phase 2, Phase 3

Global Coalition for Adaptive Research

Paris, France and 60 other locations

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations (FIGHT-209)

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting

Glioblastoma

Adult-type Diffuse Gliomas

Drug: Pemigatinib

Phase 2

Incyte

Paris, France and 80 other locations

An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) (CheckMate548)

The purpose of this study is to evaluate patients with glioblastoma that is MGMT-methylated (the MGMT gene is altered by a chemical change)....

Active, not recruiting

Brain Neoplasms

Other: Nivolumab Placebo

Drug: Nivolumab

Phase 3

Bristol-Myers Squibb (BMS)

Paris cedex 13, France and 122 other locations

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM (SONOBIRD)

are also impermeable to the passage of therapeutic molecules from the blood to the brain. The development of effective treatments against glioblastoma...

Enrolling

Glioblastoma

Recurrent Glioblastoma

Device: SonoCloud-9 (SC9)

Drug: Carboplatin

Phase 3

Carthera

Paris, France and 12 other locations

Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM (EF-32)

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting

Glioblastoma Multiforme

Device: Optune®

NovoCure

Paris, France and 132 other locations

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

(TNBC), ovarian cancer, gastric cancer, colorectal cancer (CRC), glioblastoma (GBM), biliary tract cancers (BTC), or pancreatic can...

Active, not recruiting

Glioblastoma

Gastric Cancer

Biological: Pembrolizumab

Drug: Lenvatinib

Phase 2

Merck Sharp & Dohme (MSD)

Villejuif, Val-de-Marne, France and 87 other locations

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an...

Enrolling

Locally Advanced Solid Tumor

Drug: TNG908

Phase 1, Phase 2

Tango Therapeutics

Villejuif, France and 11 other locations

A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors

Researchers are looking for a better way to treat people with solid tumors. Before a treatment can be approved for people to take, researchers do cli...

Active, not recruiting

Solid Tumors

Drug: Regorafenib, (Stivarga, BAY73-4506)

Drug: Nivolumab (Opdivo)

Phase 2

Bayer

Paris, France and 33 other locations

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

This is an open-label, multicenter, randomized, parallel, 2-arm, efficacy and safety study. Patients with GBM after failure of standard firs...

Active, not recruiting

Glioblastoma Multiforme, Adult

Drug: Berubicin

Drug: Lomustine

Phase 2

CNS Pharmaceuticals

Paris, France and 55 other locations

A Study of the Effectiveness and Safety of Nivolumab Compared to Bevacizumab and of Nivolumab With or Without Ipilimumab in Glioblastoma Patients (CheckMate 143)

alone versus bevacizumab in patients diagnosed with recurrent glioblastoma (a type of brain cancer, also known as GBM), and to eval...

Active, not recruiting

Recurrent Glioblastoma

Biological: Nivolumab

Biological: Ipilimumab

Phase 3

Bristol-Myers Squibb (BMS)

Paris cedex 13, France and 112 other locations

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Find clinical trials for Glioblastoma (GBM) in .css-epvm6{white-space:nowrap;}Paris, Île-de-France

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Glioblastoma (GBM) trials near Paris, Île-de-France, FRA:

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma (GBM AGILE)

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations (FIGHT-209)

An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) (CheckMate548)

Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM (SONOBIRD)

Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM (EF-32)

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005)

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors

A Study of Berubicin in Adult Subjects With Recurrent Glioblastoma Multiforme

A Study of the Effectiveness and Safety of Nivolumab Compared to Bevacizumab and of Nivolumab With or Without Ipilimumab in Glioblastoma Patients (CheckMate 143)

Find clinical trials for Glioblastoma (GBM) in Paris, Île-de-France