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Find clinical trials for Glioblastoma (GBM) in Philadelphia, PA

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Related conditions:

Glioblastoma
Recurrence
Brain Cancer
Glioma
Cancer
Astrocytoma
Gliosarcoma

Glioblastoma (GBM) trials near Philadelphia, PA, USA:

INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)

efficacy of INO-5401 and INO-9012 in combination with cemiplimab (REGN2810), with radiation and chemotherapy, in subjects with newly-diagnosed glioblastoma...

Active, not recruiting
Glioblastoma
Drug: Temozolomide
Biological: INO-5401

Phase 1, Phase 2

Inovio Pharmaceuticals
Inovio Pharmaceuticals

Philadelphia, Pennsylvania, United States and 20 other locations

The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...

Active, not recruiting
Glioblastoma
Glioblastoma Multiforme
Drug: Dendritic cell immunotherapy

Phase 3

Northwest Biotherapeutics
Northwest Biotherapeutics

Philadelphia, Pennsylvania, United States and 85 other locations

Evaluating the efficacy and safety of niraparib and Tumor-Treating Fields (TTFields) in recurrent glioblastoma (GBM)....

Active, not recruiting
Glioblastoma
Recurrent Glioblastoma
Procedure: Planned surgical resection
Drug: Niraparib

Phase 2

University of Pennsylvania
University of Pennsylvania

Philadelphia, Pennsylvania, United States

This research study is for Glioblastoma (GBM) patients who will be beginning Optune as part of their clinical care, which is a nove...

Enrolling
Glioma Glioblastoma Multiforme
GBM
Diagnostic Test: Whole Brain Spectroscopy Imaging Array Mapping Layout
Abramson Cancer Center at Penn Medicine
Abramson Cancer Center at Penn Medicine

Philadelphia, Pennsylvania, United States and 1 other location

Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....

Enrolling
Glioblastoma
Drug: Temozolomide
Radiation: Radiation

Phase 2, Phase 3

Global Coalition for Adaptive Research

Philadelphia, Pennsylvania, United States and 61 other locations

This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...

Active, not recruiting
Glioblastoma
Adult-type Diffuse Gliomas
Drug: Pemigatinib

Phase 2

Incyte
Incyte

Philadelphia, Pennsylvania, United States and 80 other locations

INCMGA00012, and stereotactic radiosurgery (SRS) for recurrent Glioblastoma (GBM). The investigators hypothesize that the proposed ...

Active, not recruiting
Glioblastoma
Drug: SRS
Drug: INCMGA00012

Phase 2

University of Pennsylvania
University of Pennsylvania

Philadelphia, Pennsylvania, United States

The purpose of this study is to assess progression-free survival (PFS) and overall survival (OS) in newly diagnosed Glioblastoma (GBM...

Active, not recruiting
Glioblastoma
Combination Product: IGV-001 Cell Immunotherapy
Drug: SOC: Temozolomide

Phase 2

Imvax

Philadelphia, Pennsylvania, United States and 22 other locations

To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...

Active, not recruiting
Glioblastoma Multiforme
Device: Optune®
NovoCure
NovoCure

Philadelphia, Pennsylvania, United States and 132 other locations

receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM) expr...

Enrolling
Advanced Non-Small Cell Squamous Lung Cancer
Epidermal Growth Factor Receptor C797S
Drug: BDTX-1535 monotherapy

Phase 1, Phase 2

Black Diamond Therapeutics

Philadelphia, Pennsylvania, United States and 24 other locations

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