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The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM...
Phase 3
Seattle, Washington, United States and 85 other locations
Glioblastoma (GBM) adaptive, global, innovative learning environment (GBM AGILE) is an international, seamless Phase II/II....
Phase 2, Phase 3
Seattle, Washington, United States and 61 other locations
This is an open-label, monotherapy study of pemigatinib in participants with recurrent glioblastoma (GBM) or other recurrent glioma...
Phase 2
Seattle, Washington, United States of America and 80 other locations
OKN-007 combined with temozolomide(TMZ) in patients with recurrent glioblastoma(GBM). All patients will have been previously treate...
Phase 2
Seattle, Washington, United States and 12 other locations
and tolerability of these combinations in adult participants with glioblastoma (GBM). Arm B which was previously added to the proto...
Phase 1, Phase 2
Seattle, Washington, United States of America and 10 other locations
To test the effectiveness and safety of Optune® given concomitantly with radiation therapy (RT) and temozolomide (TMZ) in newly diagnosed GBM...
Seattle, Washington, United States and 132 other locations
receptor (EGFR) resistance (EGFR C797S) mutations with or without CNS disease (in Phase 1 and Phase 2), or glioblastoma (GBM) expr...
Phase 1, Phase 2
Seattle, Washington, United States and 24 other locations
The purpose of this study is to assess the safety and tolerability of VBI-1901 in subjects with recurrent malignant gliomas (glioblastoma, o...
Phase 1, Phase 2
Seattle, Washington, United States and 11 other locations
(TNBC), ovarian cancer, gastric cancer, colorectal cancer (CRC), glioblastoma (GBM), biliary tract cancers (BTC), or pancreatic can...
Phase 2
Seattle, Washington, United States and 87 other locations
radiographically-confirmed progression of Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype, and the safety, pharmacokinetics and efficacy o...
Phase 1, Phase 2
Tacoma, Washington, United States and 1 other location
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